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Dr. Paresh Doshi
Director of Neurosurgery
Director Stereotactic and Functional Neurosurgery Dept.
Jaslok Hospital and Research Centre
Mumbai
DEEP BRAIN STIMULATION (DBS) FOR
TREATMENT RESISTANT DEPRESSION (TRD)
DR. PARESH DOSHI
Dr. Paresh Doshi
FIRST CASE IN ASIAN- AUSTRALIAN
CONTINENTS
Dr. Paresh Doshi
 History of Psychiatric disorders surgery
MGH lesional experience
Also include other indication being OCD 25 publications and 130 cases
From where do claim this, world ns paper of mayberg
Papers published in IJP
Dr. Paresh Doshi
DEEP BRAIN STIMULATON
Dr. Paresh Doshi
ABOUT FUNCTIONAL NEUROSURGERY DEPT
 Started in 1998
 Offers treatment for Parkinsons disease, movement disorders,
epilepsy, pain, spasticity and psychiatric disorders
 Pioneer in performing several surgeries for the first time in India
 Largest experience of Deep brain stimulation (>250) in India
 Member of board of directors on Asian and the World societies for
functional neurosurgery.
Dr. Paresh Doshi
WHAT IS SUBGENUAL CINGULATE GYRUS
(SCCG)
 Located in the frontal lobe
 At the base of the brain
 Close to the midline
Brain Target
Dr. Paresh Doshi
WHY SCCG
Inc activity in
depression
Dr. Paresh Doshi
MAY 2009- PSYCHOSURGERY CONSENSUS
GROUP MEETING
Dr. Paresh Doshi
GUIDELINES
 OCD and Depressionas the only confirmed indication
 Accept published inclusion and exclusion criteria for pt. selection
 Selection to be done with a 100% consensus of one neurosurgeon
and two psychiatrists
 Selected case to be further reviewed and confirmed by independent
neurologist, neurosurgeon and psychiatrist
Doshi PK, Indian J Psych, 2009
Dr. Paresh Doshi
WSSFN PSYCHIATRIC FORUM MEETING-
SHANGHAI 2011
Dr. Paresh Doshi
LONG TERM RESULTS
 62% -1yr
 42% -2yrs
 75% -3yrs
Kennedy HS, Lozano et al. Am J Psychiatry 2011; 168:502510
Dr. Paresh Doshi
BENS JOURNEY
23rd September, 2013
Dr. Paresh Doshi
DAY 1
Dr. Paresh Doshi
DAY 2
 Picture of consensus group with names tagged
Dr. Paresh Doshi
DAY 3 : FRAME FIXATION
Dr. Paresh Doshi
DAY 3: PLANNING
Dr. Paresh Doshi
DAY 3: SURGICAL SETUP
Dr. Paresh Doshi
DAY3: INTRAOPERATIVE ASSESSMENT
Dr. Paresh Doshi
Dr. Paresh Doshi
DAY 3: FINAL REWARD, BEN SMILING!!!
Dr. Paresh Doshi
THANK YOU

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Dbs for depression