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DIABETES MELLITUS
AND ITS
CASE STUDY
PRESENTED BY: ZEEL
MEVADA
GUIDED BY: Prof. JAYESH
BELADIYA
1
 Introduction of DM type 1
 Epidemiology
 Pathophysiology
 Clinical manifestation
 Diagnosis
 Treatments
 Case study
2
 The disease is characterized by an absolute
deficiency of insulin caused by an autoimmune
attack on the β cells of the pancreas.
 About 10% of the ten million diabetics in USA has
type 1 diabetes, only (2/3)is diagnosed.
 Complication: stroke, heart attack, kidney
disease, eye disease and nerve damage.
3
 Progressive destruction of pancreatic cells Auto
antibodies cause a reduction of 80% to 90% of
normal cell function before manifestations occur
4
5
Viral infection
Alteration of self cells
Auto immune response
Destruction of beta cells
Insulin deficiency
Type1 diabetes mellitus
6
-Genetic predisposition
-Exposure to virus
7
8
Weight loss
Polydipsia (excessive thirst)
Polyuria(frequent urination)
Polyphagia(excessive hunger)
Weakness and fatigue
Ketoacidosis
9
Random blood sugar test :primary screening test
for type 1 diabetes. A blood sample is taken at a
random time.
random blood sugar level
of 200 milligrams per deciliter (mg/dL), or 11.1
millimoles per liter
(mmol/L), or higher suggests diabetes.
10
Glycated hemoglobin (A1C) test: This test
indicates your child's average blood sugar level for the
past two to three months. Specifically, the test measures
the percentage of blood sugar. attached to the oxygen-
carrying protein in red blood cells (hemoglobin). An A1C
level of 6.5 percent or higher on two separate tests
indicates diabetes
11
 Blood tests to check for antibodies that are
common in type 1 diabetes
 Urine tests to check for the presence of
ketones, which also suggests type 1 diabetes
rather than type 2
12
Exogenous insulin:
– Required for all patient with type 1
DM.
Types of insulin
– Human insulin
• Most widely used type of insulin
• Cost-effective
• Likelihood of allergic reaction
13
Patients name : DP
Age: 7 year
Sex: Female
Weight: 22kg
Presenting symptoms:
 Cold& fever
 Recument stomach
 Nausea vomiting
 Lost weight
 Drinking large quantity of
water& juices
 Wetting bed
14
Random blood sugar level :14mMol/L(3.5-
10mMol/L)
 Negative for ketone
 Diagnosis of Mild ketosis was made presenting
secondary to newly diagnosed type 1 diabetes
15
 Nausea vomiting
 Lost weight
 Drinking large quantity of water& juices
 Wetting bed
16
Mechanism
17
18
Resembles to type 1 DM, negative for ketones (lab
data)
Misdiagnosed because patients have mild ketosis
19
 To reduce blood glucose to normal level
 To reduce any other risk factors which may
be life threatening
 Provide healthy diet
20
Can be advised with:
 Eat regularly ,choose high fiber food which have low
glycemic index.
 Use less butter cheese eat fewer fatty meals
 Choose yoghurt skimmed milk , steam or baked meals
To monitor regimen:
 Use alternate site for the injection
 Check blood glucose level every month
21
 Inject insulin subcutaneously on alternate site
22
23

More Related Content

diabetes case study

  • 1. DIABETES MELLITUS AND ITS CASE STUDY PRESENTED BY: ZEEL MEVADA GUIDED BY: Prof. JAYESH BELADIYA 1
  • 2.  Introduction of DM type 1  Epidemiology  Pathophysiology  Clinical manifestation  Diagnosis  Treatments  Case study 2
  • 3.  The disease is characterized by an absolute deficiency of insulin caused by an autoimmune attack on the β cells of the pancreas.  About 10% of the ten million diabetics in USA has type 1 diabetes, only (2/3)is diagnosed.  Complication: stroke, heart attack, kidney disease, eye disease and nerve damage. 3
  • 4.  Progressive destruction of pancreatic cells Auto antibodies cause a reduction of 80% to 90% of normal cell function before manifestations occur 4
  • 5. 5
  • 6. Viral infection Alteration of self cells Auto immune response Destruction of beta cells Insulin deficiency Type1 diabetes mellitus 6
  • 8. 8
  • 9. Weight loss Polydipsia (excessive thirst) Polyuria(frequent urination) Polyphagia(excessive hunger) Weakness and fatigue Ketoacidosis 9
  • 10. Random blood sugar test :primary screening test for type 1 diabetes. A blood sample is taken at a random time. random blood sugar level of 200 milligrams per deciliter (mg/dL), or 11.1 millimoles per liter (mmol/L), or higher suggests diabetes. 10
  • 11. Glycated hemoglobin (A1C) test: This test indicates your child's average blood sugar level for the past two to three months. Specifically, the test measures the percentage of blood sugar. attached to the oxygen- carrying protein in red blood cells (hemoglobin). An A1C level of 6.5 percent or higher on two separate tests indicates diabetes 11
  • 12.  Blood tests to check for antibodies that are common in type 1 diabetes  Urine tests to check for the presence of ketones, which also suggests type 1 diabetes rather than type 2 12
  • 13. Exogenous insulin: – Required for all patient with type 1 DM. Types of insulin – Human insulin • Most widely used type of insulin • Cost-effective • Likelihood of allergic reaction 13
  • 14. Patients name : DP Age: 7 year Sex: Female Weight: 22kg Presenting symptoms:  Cold& fever  Recument stomach  Nausea vomiting  Lost weight  Drinking large quantity of water& juices  Wetting bed 14
  • 15. Random blood sugar level :14mMol/L(3.5- 10mMol/L)  Negative for ketone  Diagnosis of Mild ketosis was made presenting secondary to newly diagnosed type 1 diabetes 15
  • 16.  Nausea vomiting  Lost weight  Drinking large quantity of water& juices  Wetting bed 16
  • 18. 18
  • 19. Resembles to type 1 DM, negative for ketones (lab data) Misdiagnosed because patients have mild ketosis 19
  • 20.  To reduce blood glucose to normal level  To reduce any other risk factors which may be life threatening  Provide healthy diet 20
  • 21. Can be advised with:  Eat regularly ,choose high fiber food which have low glycemic index.  Use less butter cheese eat fewer fatty meals  Choose yoghurt skimmed milk , steam or baked meals To monitor regimen:  Use alternate site for the injection  Check blood glucose level every month 21
  • 22.  Inject insulin subcutaneously on alternate site 22
  • 23. 23