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Diabetic Ketoacidosis
Walesa Ikowa
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DIABETIC KETOACIDOSIS (DKA)
 Diabetic ketoacidosis (DKA) is the state of
uncontrolled catabolism associated with
insulin deficiency, resulting in hyperglycaemia
(RBS >11mmol/L), osmotic diuresis, and
dehydration and ketonaemia (>3mmol/L)
Acidaemia (blood pH <7.3), significant
ketonuria (2+or more or standard urinalysis).
 It is the commonest endocrine emergency
usually encountered in previously diagnosed
diabetics.
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
Investigations
 Random glucose
 U/E, Creatinine
 LFTs
 FBC
 Malaria parasite
 Urinalysis
 Urine m/c/s
 Arterial blood gases
DKA(1).pptx
DKA(1).pptx
Treatment
 General resuscitation: A, B, C.
 Airway: Ensure that airway is patent.
 If comatose, insert an airway.
 If comatose and has recently vomited, insert a
NGT, aspirate and leave on open drainage.
 Breathing: Give 100% oxygen where indicated.
Bag and mask ventilation if apnoeic.
Treatment
 Circulation: Insert two large bore IV cannulae
and take blood samples.
 If shocked (Tachycardia with poor capillary
refill time or hypotension) give 20 ml/kg 0.9
saline as quickly as possible, and repeat if
necessary up to a max of 60mls/kg.
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
DKA(1).pptx
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DKA(1).pptx

  • 9. DIABETIC KETOACIDOSIS (DKA) Diabetic ketoacidosis (DKA) is the state of uncontrolled catabolism associated with insulin deficiency, resulting in hyperglycaemia (RBS >11mmol/L), osmotic diuresis, and dehydration and ketonaemia (>3mmol/L) Acidaemia (blood pH <7.3), significant ketonuria (2+or more or standard urinalysis). It is the commonest endocrine emergency usually encountered in previously diagnosed diabetics.
  • 20. Investigations Random glucose U/E, Creatinine LFTs FBC Malaria parasite Urinalysis Urine m/c/s Arterial blood gases
  • 23. Treatment General resuscitation: A, B, C. Airway: Ensure that airway is patent. If comatose, insert an airway. If comatose and has recently vomited, insert a NGT, aspirate and leave on open drainage. Breathing: Give 100% oxygen where indicated. Bag and mask ventilation if apnoeic.
  • 24. Treatment Circulation: Insert two large bore IV cannulae and take blood samples. If shocked (Tachycardia with poor capillary refill time or hypotension) give 20 ml/kg 0.9 saline as quickly as possible, and repeat if necessary up to a max of 60mls/kg.