Diabetic ketoacidosis (DKA) is an uncontrolled metabolic state associated with insulin deficiency that results in high blood sugar, dehydration, and ketones in the blood and urine. It is characterized by hyperglycemia over 11mmol/L, osmotic diuresis, dehydration, ketonemia over 3mmol/L, and blood pH below 7.3 with significant ketonuria. DKA is commonly seen in people with previously diagnosed diabetes and requires general resuscitation, ensuring an open airway, oxygen supplementation, intravenous fluids, and treatment of acidosis.
9. DIABETIC KETOACIDOSIS (DKA)
Diabetic ketoacidosis (DKA) is the state of
uncontrolled catabolism associated with
insulin deficiency, resulting in hyperglycaemia
(RBS >11mmol/L), osmotic diuresis, and
dehydration and ketonaemia (>3mmol/L)
Acidaemia (blood pH <7.3), significant
ketonuria (2+or more or standard urinalysis).
It is the commonest endocrine emergency
usually encountered in previously diagnosed
diabetics.
23. Treatment
General resuscitation: A, B, C.
Airway: Ensure that airway is patent.
If comatose, insert an airway.
If comatose and has recently vomited, insert a
NGT, aspirate and leave on open drainage.
Breathing: Give 100% oxygen where indicated.
Bag and mask ventilation if apnoeic.
24. Treatment
Circulation: Insert two large bore IV cannulae
and take blood samples.
If shocked (Tachycardia with poor capillary
refill time or hypotension) give 20 ml/kg 0.9
saline as quickly as possible, and repeat if
necessary up to a max of 60mls/kg.