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Insulin regimens
Regimen Type of insulin Comments
Once a day single
dose
Intermediate
Or
Long acting
At bed time
 One injection
should cover
noon meal
 1 injection
will last 24hrs
with no
peaks and
less chance
for
hypoglycemi
a
 Does not
cover
postprandial
blood sugars
Twice a day
Split mix dose
NPH regular
Or NPH rapid
Before breakfast,
and at dinner
2 injections provide
coverage for 24hrs
Three times a day
Combination of
mixed and single
dose
NPH regular
Or NPH rapid
Before breakfast
and dinner as well
as at bed time
Three injections
provide coverage or
24hrs
Particularly during
early hours
Four times a day
Multiple dose
Regular or rapid
injection
Before breakfast,
lunch and dinner
AND
NPH at bed time
More flexibility is
allowed at meal
times and for
amount of food
intake
Good postprandial
control
Basal bolus Before breakfast,
lunch and dinner
Long acting once a
Four injection
srequired per day
day, usually at
bedtime

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  • 1. Insulin regimens Regimen Type of insulin Comments Once a day single dose Intermediate Or Long acting At bed time  One injection should cover noon meal  1 injection will last 24hrs with no peaks and less chance for hypoglycemi a  Does not cover postprandial blood sugars Twice a day Split mix dose NPH regular Or NPH rapid Before breakfast, and at dinner 2 injections provide coverage for 24hrs Three times a day Combination of mixed and single dose NPH regular Or NPH rapid Before breakfast and dinner as well as at bed time Three injections provide coverage or 24hrs Particularly during early hours Four times a day Multiple dose Regular or rapid injection Before breakfast, lunch and dinner AND NPH at bed time More flexibility is allowed at meal times and for amount of food intake Good postprandial control Basal bolus Before breakfast, lunch and dinner Long acting once a Four injection srequired per day