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DRUG DEPENDENCE AND
ABUSE
SUBASH KUMAR PATRA
5TH SEMESTER
SCBMCH
WHY ?
Drug Dependence and Abuse
Drug Dependence and Abuse
Drug Dependence and Abuse
Drug Dependence and Abuse
Drug Dependence and Abuse
Drug Dependence and Abuse
Drug Dependence and Abuse
Drug Dependence and Abuse
DRUG
 Any substance other than that required for
maintenance of normal health, when
administered to any living organism modifies
one or more functions.
 DRUG ABUSE: Persistent or sporadic excessive
drug use inconsistence with or unrelated to
acceptable medical practice
HISTORY
 Ebers Papyrus (1500 BC): 1st drug of abuse- OPIUM
 Epistratos (300 BC): abuse potential
 17-18th century: Liquor
 19th century: Tobacco
: Cocaine
 Now: Designer drugs
TERMINOLOGIES
 PHYSICAL DEPENDENCE: Appearance of
withdrawal phenomena when a chronically
administered drug is discontinued or displaced
from its receptor
 Polysubstance dependence- RAINBOW parties
EVER CONFUSED?
DRUG HABITUATION
 DEPENDENCE
 CRAVING
 RELAPSE
 INCREASE IN DOSE
 WITHDRAWAL SYMPTOMS
 PREOCCUPATION
DRUG ADDICTION
ROUTES OF DRUG ADMINISTRATION
 ORAL
 INHALATIONAL
SNIFFING
BAGGING
HUFFING
 SNORTING  cocaine
 INJECTION
 SKIN POPPING (s.c.)
 MAIN LINING (i.v.)
# Drug abusers elbow
FATAL RESULTS
 Overdose
 Contaminant toxicity
 Infection
 Gangrene
 Anaphylactic reaction
CAN A NEWBORN SUFFER FROM
WITHDRAWAL SYMPTOMS BORN OUT OF
ADDICTED MOTHER?
 Features:
 Hyperactivity
 Muscular twitching
 Convulsions
newspaper
Seen this movie?
 Body packer syndrome
 Body packers/ Surgical mules/ Courier
 Body Stuffers
 Hot shot
EPIDEMIOLOGY
 5% of population
 Most commonly abused drugs:
Legally
 Caffeine
 Nicotine
 Alcohol
Illegally
 Cannabis
 Cocaine
 Heroine
CANNABIS
Marijuana Ganja Bhang Hashish Hash oil
 Majoon: (sweet) Bhang+Honey+ghee  Run Amok
COCAINE
 Why called Crack?
 Magnan sign/ Formication
 Bromptons cocktail
 Pain relief in cancer
HEROINE
 Why the name Heroin?
 Cutting
 Booting
 Flash blood
 SPEED BALL: IV Heroine + cocaine
 Cotton fever (Pantoea agglomerans)
ALCOHOL
 Stages of alcohol poisoning
 Stage of Excitement (0.05-0.1%)
 Stage of Incoordination (0.15-
0.25%)
 Stage of Stupor (0.3-0.5%)
 McEwens Sign
 Wernicks Encephalopathy
 Korsakoffs Psychosis
 Delirium Tremens
MANAGEMENT
TREATMENT DRUG REHAB. DRUG COURT
NARCOTIC ACT
 NARCOTIC DRUGS AND PSYCHOTROPIC SUBSTANCES ACT
(1985)
 PREVENTION OF ILLICIT TRAFFIC IN NARCOTIC DRUGS
AND PSYCHOTROPIC SUBSTANCES ACT (1988)
Drug Dependence and Abuse
Drug Dependence and Abuse

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