DRUGS FOR FUNGAL/ SKIN DISORDERS.
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This document discusses several topical antifungal drugs used to treat fungal and skin disorders, including clotrimazole, bifonazole, and miconazole nitrate. It provides the generic and brand names, description/dosage, indications for use, advantages/side effects, and potential drug interactions for each drug. The document was submitted by 8 pharmacy students to Dr. Akhtar Rasul as an assignment on topical antifungals used in community pharmacy practice.
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The document presents an overview of antifungal drugs, detailing the classification of fungi and the mechanisms of action for various antifungal agents. It explains how the composition of fungal cell walls and membranes influences drug effectiveness and resistance, and it categorizes antifungal drugs based on their action against fungal infections. Key antifungal drugs discussed include azoles, amphotericin B, flucytosine, griseofulvin, and terbinafine, each with distinct mechanisms impacting fungal cell survival.Presentation1
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Fungal infections, or mycoses, can range from superficial conditions affecting skin and mucous membranes to life-threatening systemic infections. Treatment typically involves antifungal drugs, which include polyenes, azoles, and antimetabolites, each with distinct mechanisms of action and pharmacokinetics. The document discusses specific drugs like amphotericin B and griseofulvin, detailing their therapeutic uses, adverse effects, and spectrum of activity against various fungi.Ad
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- 1. DRUGS FOR FUNGAL/SKIN DISORDERS ANTIFUNGALS/TOPICAL Submittedto: Dr Akhtar Rasul 9/23/2013
- 2. DRUGS USED TO TREAT FUNGAL/SKIN DISORDERS (ANTIFUNGALS/TOPICAL) ASSIGNMENT OF COMMUNITY PHARMACY Reference:PharmaGuide Submittedto:Dr. Akhtar Rasul. Submitted By: Muavia Sarwar (Roll No. 12) Israr ul Haq (Roll No. 46) Atta ur Razzaq (Roll No. 50) Waqas Haider (Roll No. 63) Imran Ali (Roll No. 60) Awais Asghar (Roll No. 74) Aurangzeb (Roll No. 83) Shoaib Nawaz (Roll No. 91) Mehtab Saeed (Roll No. 102-09) SESSION 2010-15 Faculty of Pharmacy University OF Sargodha
- 3. DRUGS USED TO TREAT FUNGAL/SKIN DISORDERS (ANTIFUNGALS/TOPICAL) ASSIGNMENT OF COMMUNITY PHARMACY Reference:PharmaGuide Submittedto:Dr. Akhtar Rasul. Generic Name Available Brands Company Name Description/Dose Indications/Uses Adv/Side Effects Interaction s Clotrimazole Calotren Clomazole Topical Clozole Clonil Skin Caylex PharmaWise Pearl Mediceena Topical Cream. Clotrimazole1%. 10gm or 20gm pack. Apply sparingly two or three times daily until two weeks after apparent cure. Fungal & gram +ve bacterial infections of skin and nail. Fungal otitis externa. Vulvitis Balanitis Treatment of partner to prevent reinfection Local mild burning Irritation. Hypersensitivity reactions. With Polyene antibiotics Bifonazole Benoder Benoder Caraway Wisdom Topical Cream Bifonazole 0.01gm per gm 15gm pack Apply sparingly 1 time daily until two weeks after apparent cure. Mycoses of skin caused by: Dermatophytes Yeasts Moulds Other fungi Local reactionsi.e. Burning Itching No data found
- 4. DRUGS USED TO TREAT FUNGAL/SKIN DISORDERS (ANTIFUNGALS/TOPICAL) ASSIGNMENT OF COMMUNITY PHARMACY Reference:PharmaGuide Submittedto:Dr. Akhtar Rasul. GenericName Available Brands Company Name Description/Dose Indications/Uses Adv/Side Effects Interactions Miconazole Nitrate Dermicon Dermistat Friends Varioline Topical Cream Miconazole nitrate 2% 10gm pack Skin:Apply once or twice daily until 10 days after lesions havehealed. Nails:Apply thinly once daily until newnail growth established Fungal Gram +ve bacterial infections of skin and nail. Vaginal yeast infections. Local reactions i.e. Burning Itching Redness No data found.