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Charles Kent Ltd
ePortfolio
Charles Kent Ltd
Visual Communications Specialist
Diagrams
京艶韓看姻艶
After
ANP
Hypertrophic gene program
Ca2+
Ca2+
Calcineurin
NFAT
NFATGATA
CaMKII
PKG
RGS2
Angiotensin II
TRPC 3/6 GPCR
GC-A
TRRC
MCP
IP3
NFAT
P
P
PLC
RGS2
Goq
GTP
京艶韓看姻艶
Pre-launch Launch Post-Launch
Online resource
for oncologists
and pathologists
a therapy area
portal approach
Brand website
New MOAfor
EGFR-TKI
Plugging into the
established
communication networks
Congress activities
EGFRtesting
app
Augmented reality/
interactive sales aids
Patient portal
Materials
produced in
conjunction
with patient
organisations
Multichannel integration:Our approach is to ensure activities are integrated into the communication strategy to
enable maximum reach with key stakeholders with consistent messaging across all channels
Booth materials
粥韓岳艶姻
PRE-LAUNCH LAUNCH POST-LAUNCH
Congress activities
Plugging into the
established
communication networks
Patient portal
Online resource for
oncologists and
pathologists a
therapy area
portal approach
New MOA for
EGFR-TKI
Materials
produced in
conjunction
with patient
organisationsBooth materials
Augmented reality/
interactive sales aids
Brand website
EGFR
testing app
> Multichannel integration: Our approach is to ensure activities are integrated into the communication
strategy to enable maximum reach with key stakeholders with consistent messaging across all channels
京艶韓看姻艶
Induction +2842d post
cycle 4,
Maintenance 25m post
cycle 4
Product A
375 mg/m2 IV
Product A
375 mg/m2 IV
 Relapsed CD20+
iNHL
 Prior response
>6 mo to last
Product A rx
ABC101
( Product B )
1000 mg IV
ABC101
( Product B )
1000 mg IV
9
PD Discontinue
Treatment
CT/PET

CT/PET

CT CT CT
CT
   
3m 6m 12m
18m
CT

25m
Randomized phase II trial comparing ABC101 (Product B) with product A in patients
with relapsed CD20+ indolent B-cell NHL
w1 w2 w3 w4 m2 m4 m6 m24

RANDOMIZATION
EndofInduction
EndofMaintenance
粥韓岳艶姻
 Relapsed CD20+
iNHL
 Prior response
6 mo to last
product A rx
Induction Maintenance
Product A
375 mg/m2 IV
Product A
375 mg/m2 IV
ABC101
(Product B)
1000 mg IV
ABC101
(Product B)
1000 mg IV
End of
induction
End of
maintenance
+2842d
post cycle 4
25m post
cycle 4
CT/PET
Randomization
CT CT CT CT CTCT/PET
3m 6m 12m 18m 25m
PD discontinue treatment
Randomized phase II trial comparing ABC101 (Product B) with product A
in patients with relapsed CD20+ indolent B-cell NHL
w1 w2 w3 w4 m2 m4 m6 m24
京艶韓看姻艶
粥韓岳艶姻
Standardised measures to
track/quantify symptoms
(eg ACT, ASQ, CAT)
Peak flow diary results,
spirometry results/pulmonary
function tests (FEV1)
If patient presents to HCP (outside of a
routine consultation) this is first indicator
that they may not be controlled
Basic questions about symptoms
experienced and exposure to triggers
(many have a battery of questions they use)
Symptom
quantification
Objective
clinical
measures
Symptom report /
questioning
Patient presentation
ACT and ASQ are useful but we
dont go through each of them,
just pick specific questions.
SPECIALIST, Dublin
Ultimately it is a clinical syndrome
so we are looking at that rather
than lab measures to monitor.
SPECIALIST, Dublin
If they are not
seeing us we hope
they are controlled.
NURSE, Manchester
Less
used
Layout
Charles Kent Ltd ePortfolio
Charles Kent Ltd ePortfolio
Charles Kent Ltd ePortfolio
Charles Kent Ltd ePortfolio
Figure Redrawing for Posters,
Presentations & Manuscripts
京艶韓看姻艶
粥韓岳艶姻LVEDV(ml)
0
100
200
300
LVESV(ml)
0
100
200
SV(ml)
0
40
60
80
20
*
EF(%)
0
20
40
60
TPR
(dyne-sec-cm5)
0
2000
3000
ANF(pg/ml)
0
40
60
20
* *
* *
**
* *
* *
*
**
1000
* *
Controls CHF Controls CHF
Base 60 120 Base 60 120 Base 60 120 Base 60 120
Time (minutes) Time (minutes)
**
* *
* *
**
* *
**
*
*
*
*
京艶韓看姻艶
Comparator 1  Overall Survival
Prior Platinum Exposure
HR 1.23 (95% CI 0.45-6.78)
RR: 12% (CP) vs 34% (TP)
HR 1.23 (95% CI 0.45-6.78)
RR: 12% (CP) vs 34% (TP)
Prior Comparator A No Prior Comparator A
Comparator A backbone
Comparator A backbone
Comparator B backbone
Comparator B backbone
粥韓岳艶姻
Comparator 1  Overall Survival
Prior Platinum Exposure`
Proportionsurviving
Months on Study
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1.0
0 2412 186
Prior Comparator A No Prior Comparator A
Proportionsurviving
Months on Study
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1.0
0 2412 186
HR: 1.23 (95% CI 0.456.78)
RR: 12% (CP) vs 34% (TP)
HR: 1.23 (95% CI 0.456.78)
RR: 12% (CP) vs 34% (TP)
Comparator
A
Comparator
B
Alive 123 45
Dead 67 89
Total 112 345
Comparator
A
Comparator
B
Alive 123 45
Dead 67 89
Total 112 345
京艶韓看姻艶
粥韓岳艶姻SV(ml)
0
50
100
ANF(pg/ml)
0
60
20
180 280 180 280
Untreated CEI
Base
60
120
Volume Expansion
京艶韓看姻艶
粥韓岳艶姻
Software Applications
Advanced User:
Adobe Illustrator CC
Adobe Photoshop CC
Adobe InDesign CC
Adobe Acrobat
Microsoft Powerpoint (2013)
Microsoft Word (2013)
Microsoft Excel (2013)
Quark Express

More Related Content

Charles Kent Ltd ePortfolio

  • 2. Charles Kent Ltd Visual Communications Specialist
  • 6. 京艶韓看姻艶 Pre-launch Launch Post-Launch Online resource for oncologists and pathologists a therapy area portal approach Brand website New MOAfor EGFR-TKI Plugging into the established communication networks Congress activities EGFRtesting app Augmented reality/ interactive sales aids Patient portal Materials produced in conjunction with patient organisations Multichannel integration:Our approach is to ensure activities are integrated into the communication strategy to enable maximum reach with key stakeholders with consistent messaging across all channels Booth materials
  • 7. 粥韓岳艶姻 PRE-LAUNCH LAUNCH POST-LAUNCH Congress activities Plugging into the established communication networks Patient portal Online resource for oncologists and pathologists a therapy area portal approach New MOA for EGFR-TKI Materials produced in conjunction with patient organisationsBooth materials Augmented reality/ interactive sales aids Brand website EGFR testing app > Multichannel integration: Our approach is to ensure activities are integrated into the communication strategy to enable maximum reach with key stakeholders with consistent messaging across all channels
  • 8. 京艶韓看姻艶 Induction +2842d post cycle 4, Maintenance 25m post cycle 4 Product A 375 mg/m2 IV Product A 375 mg/m2 IV Relapsed CD20+ iNHL Prior response >6 mo to last Product A rx ABC101 ( Product B ) 1000 mg IV ABC101 ( Product B ) 1000 mg IV 9 PD Discontinue Treatment CT/PET CT/PET CT CT CT CT 3m 6m 12m 18m CT 25m Randomized phase II trial comparing ABC101 (Product B) with product A in patients with relapsed CD20+ indolent B-cell NHL w1 w2 w3 w4 m2 m4 m6 m24 RANDOMIZATION EndofInduction EndofMaintenance
  • 9. 粥韓岳艶姻 Relapsed CD20+ iNHL Prior response 6 mo to last product A rx Induction Maintenance Product A 375 mg/m2 IV Product A 375 mg/m2 IV ABC101 (Product B) 1000 mg IV ABC101 (Product B) 1000 mg IV End of induction End of maintenance +2842d post cycle 4 25m post cycle 4 CT/PET Randomization CT CT CT CT CTCT/PET 3m 6m 12m 18m 25m PD discontinue treatment Randomized phase II trial comparing ABC101 (Product B) with product A in patients with relapsed CD20+ indolent B-cell NHL w1 w2 w3 w4 m2 m4 m6 m24
  • 11. 粥韓岳艶姻 Standardised measures to track/quantify symptoms (eg ACT, ASQ, CAT) Peak flow diary results, spirometry results/pulmonary function tests (FEV1) If patient presents to HCP (outside of a routine consultation) this is first indicator that they may not be controlled Basic questions about symptoms experienced and exposure to triggers (many have a battery of questions they use) Symptom quantification Objective clinical measures Symptom report / questioning Patient presentation ACT and ASQ are useful but we dont go through each of them, just pick specific questions. SPECIALIST, Dublin Ultimately it is a clinical syndrome so we are looking at that rather than lab measures to monitor. SPECIALIST, Dublin If they are not seeing us we hope they are controlled. NURSE, Manchester Less used
  • 17. Figure Redrawing for Posters, Presentations & Manuscripts
  • 19. 粥韓岳艶姻LVEDV(ml) 0 100 200 300 LVESV(ml) 0 100 200 SV(ml) 0 40 60 80 20 * EF(%) 0 20 40 60 TPR (dyne-sec-cm5) 0 2000 3000 ANF(pg/ml) 0 40 60 20 * * * * ** * * * * * ** 1000 * * Controls CHF Controls CHF Base 60 120 Base 60 120 Base 60 120 Base 60 120 Time (minutes) Time (minutes) ** * * * * ** * * ** * * * *
  • 20. 京艶韓看姻艶 Comparator 1 Overall Survival Prior Platinum Exposure HR 1.23 (95% CI 0.45-6.78) RR: 12% (CP) vs 34% (TP) HR 1.23 (95% CI 0.45-6.78) RR: 12% (CP) vs 34% (TP) Prior Comparator A No Prior Comparator A Comparator A backbone Comparator A backbone Comparator B backbone Comparator B backbone
  • 21. 粥韓岳艶姻 Comparator 1 Overall Survival Prior Platinum Exposure` Proportionsurviving Months on Study 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0 0 2412 186 Prior Comparator A No Prior Comparator A Proportionsurviving Months on Study 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0 0 2412 186 HR: 1.23 (95% CI 0.456.78) RR: 12% (CP) vs 34% (TP) HR: 1.23 (95% CI 0.456.78) RR: 12% (CP) vs 34% (TP) Comparator A Comparator B Alive 123 45 Dead 67 89 Total 112 345 Comparator A Comparator B Alive 123 45 Dead 67 89 Total 112 345
  • 23. 粥韓岳艶姻SV(ml) 0 50 100 ANF(pg/ml) 0 60 20 180 280 180 280 Untreated CEI Base 60 120 Volume Expansion
  • 27. Advanced User: Adobe Illustrator CC Adobe Photoshop CC Adobe InDesign CC Adobe Acrobat Microsoft Powerpoint (2013) Microsoft Word (2013) Microsoft Excel (2013) Quark Express