1. The testes begin developing in the abdomen around the third month in utero and normally descend into the scrotum between the seventh and ninth months of fetal development.
2. Factors that can affect the descent of the testes include hormonal factors, genetics, premature birth, and the mother's alcohol/cigarette use during pregnancy.
3. Undescended testes occur in approximately 3% of full-term infants and have higher risks of infertility, testicular cancer, and torsion. Evaluation and early surgery are recommended to lower these risks.
5. Testes begin to develop
inside the ? by the
? month IU, and
descend into the scrotum
during ? to ? mth of
fetal development.
Empty Scrotum
TarigHHagAli
6. Iliac fossa 3rd-5th month
Deep inguinal ring 7th month
Superficial ring 8th month
Scrotum 9th month
Empty Scrotum
TarigHHagAli
7. Factors which affect descent:
Empty Scrotum
TarigHHagAli
What are the factors which affect descent
8. Factors which affect descent:
1- shortening of the gubernaculum.
2- hormonal factors:testesterone,HGnh
3- Insulin-Like 3 (INSL3)
4- differential growth of body wall in
relation to a relatively immobile
gubernaculum.
5- increased intra-abdominal pressure
Others???
Empty Scrotum
TarigHHagAli
Theories
10. Risk Factors for incomplete descent?
Empty Scrotum
TarigHHagAli
Premature birth.
Low birth weight.
Family history. ?? Genetic.
Abdominal wall defect.
Alcohol use & Cigarette smokingby the mother.
Assisted reproduction (IVF)
Parents' exposure to toxins??? Pesticides ??
Down syndrome.
Gurney Nat Rev Urol. 2017
11. DESCENT OF THE TESTES
Complete by 1 month
post birth
Tarig H Hag Ali
12. 70% of full term crypto-orchid
testes and up to 95% of
premature crypto-orchid testes will
spontaneously descend by 1year
Empty Scrotum
TarigHHagAli
N B
35. UNDESCENDED TESTES
Early orchidopexy may improve fertility
No evidence that it reduces risk of malignancy
Empty Scrotum
TarigHHagAli
36. ECTOPIC TESTES
Less < 5 %
descended properly from the abdomen
.. but mis-directed outside the external
inguinal to an abnormal position.
presumably due to an abnormally
positioned distal extension of the
gubernaculum.
function normally.
Empty Scrotum
TarigHHagAli