This document discusses the epidemiology of dental caries. It begins by defining dental caries and exploring early theories about its etiology. It then examines the epidemiological triad of host, microbes, and environment. Several key studies are summarized that demonstrate the role of diet, particularly sugars, in promoting dental caries. The Vipeholm study showed that increased sugar intake leads to more caries, while the Hopewood House and Turku sugar studies found reductions in caries by limiting sugars and consuming xylitol respectively. Genetic factors and other lifestyle influences on dental caries prevalence are also briefly mentioned.
2. DENTAL CARIES
It is defined as a microbial disease of the calcified tissues
of the teeth characterized by the dimeneralization of
inorganic portion and dissolution of the organic portion of
the tooth.
- Shafer, Hine & Levy
11. PROTEOLYSIS CHELATION
THEORY SCHATZ & MARTIN
(1955)
Products of bacterial action + enamel/ dentin/
salivary constituents chelates with calcium.
Chelates can be formed at neutral/ alkaline
pH
Demineralization could arise without acid
formation.
25. MICROBES VS TOOTH
Pre requisite
Single type
capable
Acid production pre
requisite
Strep strains
extracellular
dextrans/ levans
Organisms varying
capacity
26. CARIOGENIC PLAQUE -
PROPERTIES
Rate of sucrose
consumption higher
Synthesize more
intracellular
polysaccharides
More lactic acid
Twice extra cellular
polysaccharides
Strep mutans higher
Strep sanguis &
Actinomyces - lower
39. HOPEWOOD HOUSE STUDY
SULLIVAN (1958)
The dental status of children between 3 and
14 years of age residing at Hopewood House,
New South Wales was studied longitudinally
for 10 years.
41. INFERENCE
PLACE % CARIES ACTIVITY
Hopewood 53 Caries free
State School
Children
0.4 Caries free
75 Poor Oral hygiene &
gingivitis
DENTAL CARIES CAN BE REDUCED BY DIET IN
INSTITUTIONALIZED CHILDREN, WITHOUT BENEFICIAL
EFFECTS OF FLUORIDE & IN PRESENCE OF UNFAVOURAVLE
ORAL HYGIENE.
42. TURKU SUGAR STUDY
SCHEININ, MAKINEN (1975)
STUDY PERIOD = 2 years; n = 125
SUCROSE
N = 35
FRUCTOS
E
N = 38
XYLITOL
N = 52
43. INFERENCE
1. A dramatic reduction in the incidence of
dental caries was found after 2 years of
xylitol consumption
2. Fructose was as cariogenic as sucrose for
the first 12 months but became less so at the
end of 24 months.
3. Chewing of xylitol gum produced an anti
cariogenic effect.
44. SEVENTH DAY ADVENTIST
CHILDREN STUDY
Limitation of sugar
sticky elements,
highly refined
starches, between
meal snacking.
Level of DC was
much lower.
45. HEREDITARY FRUCTOSE
INTOLERANCE
Level of DC lower
Vitamins A, D, K, B complex and calcium &
phosphorus, fluoride, amino acid like lysin &
fats has an inhibitory effect on dental caries.
46. OTHERS
GEOGRAPHY: DMFT increasing in developing
countries.
SOIL: Selenium increase DC; Molybdenum &
Vanadium decrease DC
URBANIZATION DC increases.
CLIMATE Sunlight decrease DC; Rainfall
increase DC.