Fatty liver- General metabolism, biochemistry
- 4. Role of liver in fat metabolism • Secretion of bile salts • Synthesis of fatty acid, triacylglycerols(transported as VLDL in blood) and phospolipids. • Oxidation of fatty acids • Production of lipoproteins • Production of ketone bodies • Synthesis and excretion of cholesterol.
- 8. Excess calorie intake Excess calories in the form of carbohydrates Deposited as fat Obesity accompanied by fatty liver
- 9. ALCOHOLISM Most common cause Alcohol oxidized to acetaldehyde Increased quantities of NADH NADH converts oxaloacetate to malate FA accumulates because of deficiency of OAA(oxidation of acetyl CoA through TCA cycle is reduced)
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