This document analyzes and compares the financial performance of Pfizer and Novartis for 2013-2012. It includes analysis of profitability ratios like gross profit margin, operating profit margin and net profit margin. Liquidity ratios like current ratio and quick ratio are examined. Solvency is assessed using debt ratio and debt-to-equity. Efficiency is evaluated through total asset turnover, fixed asset turnover, receivables turnover and inventory turnover. Pfizer generally performed better than Novartis based on these financial metrics.