Food and drug intrection
Download as PPTX, PDF
1 like228 views
This document discusses food and drug interactions and provides examples. It notes that food can make drugs less or more effective, or cause harmful effects in the body. Grapes or grape juice can interact with statin drugs like atorvastatin and lovastatin by blocking enzymes in the liver that break down the statins, causing more of the drugs to enter the body and potentially lead to side effects like muscle breakdown or liver damage. The document also gives examples of interactions between vitamin K and the blood thinner warfarin, calcium and anti-seizure medications, and liquorice with the heart drug digoxin. It recommends establishing dietary systems to avoid interacting foods and educating patients to prevent these interactions.
Food and drug intrection
- 1. Assignment 1st Pharmacy Practice Food and Drug Interactions Submitted By :- Vijay Kumar ( 75161827) Student of B.Pharmacy (7th sem.) MMSOP
- 2. INTRODUCTION :- A food drug interaction is a situation when an active chemicals in a drug reacts to the nutrients and food item and cause less effective then expected More effective then expected May cause the effect in the body that could be extremely harmful to our body Food is either restricted or provided at a time before or after the medication has been given to prevent any Food-Drug interaction.
- 4. Food and Drugs that do not work well together Grapes /grapes juice with cholesterol lowering Drugs Eg :- Atorvastatin's ,Lovastatin's These statins drugs are broken down in liver by enzyme. The grapes/grapes juice can block the action of these enzymes ,which would cause the more of statins to enter the body than intended
- 6. Side effects cause by the interaction of statins and grapes Muscle breakdown Liver damage Increased blood sugar Neurological side effects Digestive problems Therefor grapes juice are not offered / given to the patents which are using statins
- 7. Another examples of food and drug intrection Vitamin K (increased the clotting factor ) with Warfarin ( thin the blood) Calcium with the anti seizures drugs (e.g. phenytoin sodium) Liquorice with digoxin ( used to treat heart failure and irregular heartbeats disorder )
- 9. How to avoid food drugs interactions By establishing an system dietary is aware to what food to avoid at the time of medication Representative should be educated on potential food drug interactions Discuss food preferences and alternative of the food that are on menu. Read food labels
- 10. Regards vijay kumar