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Gametogenesis and fertilization
By
Dr. Ansari
Chairperson & Prof. Anatomy
RAKCODS. RAKMHSU
(for BDS students)
12/18/2014 1
The learning outcomes are
? The students are able to chart out the steps in
Gametogenesis occurring in male persons and
steps of oogenesis occurring in female subjects.
? The result of spermatogenesis and
spermiognenesis.
? The result of oogenesis.
? The fertilization is the result of union between
the male and female gametes occurring in the
female reproductive organs.
12/18/2014 2
Formation of male gametes is called
spermatogenesis
? It occurs in the testis of an adult male.
? The mother cells are called as spermatogonia.
? Each spermatogonium consists of 2n number of
chromosomes.
? In human it is 46 chromosomes (22autosomes
and XX/XY sexosomes).
? The supporting cells are called as sertoli cells.
? They help in providing nutrition and helps in
spermiognenesis-maturation of sperms.
12/18/2014 3
There are three steps in spermatogenesis
? 1) Meiosis I, during which the number of
chromosomes in the cell is reduced to half or 23
chromosomes each;
? 2) Meiosis II, during which each haploid cell forms
spermatids; and
? 3) Spermiogenesis, during which each spermatid
develops into a sperm cell with a head and tail.
? The entire process of spermatogenesis takes
about 64 days.
12/18/2014 4
12/18/2014 5
The spermiogensis is regulated by
Sertoli cells
12/18/2014 6
The oogenesis occur in female
reproductive organ- ovary
12/18/2014 7
The fertilization is the union of male and
female gametes-it occurs in uterine tubes
12/18/2014 8
12/18/2014 9
The result of fertilization
? Stimulates the secondary oocyte to complete meiosis.
? Restores the normal diploid number of chromosomes (46).
? Results in variation of human species as maternal and paternal
chromosomes intermingle.
? The embryo contains only maternal mitochondria because the sperm
mitochondria are dispersed into the egg cytoplasm and discarded.
? Determines the sex of the embryo.
? The sex chromosome (Y or X) carried by the successful sperm determines
embryonic sex.
? The sperm can only survive 48 hours within the female genital tract.
12/18/2014 10
Monozygotic twin
? A fertilized, single egg
splits into two
developing zygotes at a
very early stage.
? Identical twins; same
sex.
12/18/2014 11
Dizygotic twin:-
? Result from the
fertilization by two
sperms & two separate
ova that have reached
maturation at the same
time.
? Not identical twins; can
be different sexes
? Incidence increases
with age of the mother
12/18/2014 12
Conjoint twins- Siamese twins
? Conjoint twins will result
when the germ disk
duplicates itself and will
not get separated out at a
particular point and
remain joined.
? Whole two individuals
will develop with parts
attached with each other.
? Here it is a craniopagus.
12/18/2014 13
References
? http://education-
portal.com/academy/lesson/oogenesis-how-
the-female-reproductive-system-produces-
eggs.html#lesson
? http://www.youtube.com/watch?v=BFrVmDg
h4v4
? http://www.tutorsglobe.com/getanswer/proc
ess-of-fertilization-in-human-beings-
908778.aspx
12/18/2014 14

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Gametogenesis and fertilization

  • 1. Gametogenesis and fertilization By Dr. Ansari Chairperson & Prof. Anatomy RAKCODS. RAKMHSU (for BDS students) 12/18/2014 1
  • 2. The learning outcomes are ? The students are able to chart out the steps in Gametogenesis occurring in male persons and steps of oogenesis occurring in female subjects. ? The result of spermatogenesis and spermiognenesis. ? The result of oogenesis. ? The fertilization is the result of union between the male and female gametes occurring in the female reproductive organs. 12/18/2014 2
  • 3. Formation of male gametes is called spermatogenesis ? It occurs in the testis of an adult male. ? The mother cells are called as spermatogonia. ? Each spermatogonium consists of 2n number of chromosomes. ? In human it is 46 chromosomes (22autosomes and XX/XY sexosomes). ? The supporting cells are called as sertoli cells. ? They help in providing nutrition and helps in spermiognenesis-maturation of sperms. 12/18/2014 3
  • 4. There are three steps in spermatogenesis ? 1) Meiosis I, during which the number of chromosomes in the cell is reduced to half or 23 chromosomes each; ? 2) Meiosis II, during which each haploid cell forms spermatids; and ? 3) Spermiogenesis, during which each spermatid develops into a sperm cell with a head and tail. ? The entire process of spermatogenesis takes about 64 days. 12/18/2014 4
  • 6. The spermiogensis is regulated by Sertoli cells 12/18/2014 6
  • 7. The oogenesis occur in female reproductive organ- ovary 12/18/2014 7
  • 8. The fertilization is the union of male and female gametes-it occurs in uterine tubes 12/18/2014 8
  • 10. The result of fertilization ? Stimulates the secondary oocyte to complete meiosis. ? Restores the normal diploid number of chromosomes (46). ? Results in variation of human species as maternal and paternal chromosomes intermingle. ? The embryo contains only maternal mitochondria because the sperm mitochondria are dispersed into the egg cytoplasm and discarded. ? Determines the sex of the embryo. ? The sex chromosome (Y or X) carried by the successful sperm determines embryonic sex. ? The sperm can only survive 48 hours within the female genital tract. 12/18/2014 10
  • 11. Monozygotic twin ? A fertilized, single egg splits into two developing zygotes at a very early stage. ? Identical twins; same sex. 12/18/2014 11
  • 12. Dizygotic twin:- ? Result from the fertilization by two sperms & two separate ova that have reached maturation at the same time. ? Not identical twins; can be different sexes ? Incidence increases with age of the mother 12/18/2014 12
  • 13. Conjoint twins- Siamese twins ? Conjoint twins will result when the germ disk duplicates itself and will not get separated out at a particular point and remain joined. ? Whole two individuals will develop with parts attached with each other. ? Here it is a craniopagus. 12/18/2014 13