The document discusses the process of gas exchange in the human respiratory system. It involves 3 main steps: 1) ventilation through inspiration and expiration, 2) external respiration where gas exchange occurs between air in the lungs and blood, and 3) internal respiration where gases diffuse between blood and tissues. The main organs involved are the nose, pharynx, larynx, trachea, bronchi, and lungs. In the lungs, gas exchange takes place in the alveoli which are lined with blood capillaries, allowing for diffusion of oxygen into the blood and carbon dioxide out. Several pulmonary diseases and the effects of smoking on the lungs are also outlined.
2. BREATHING.
A SEQUENCE OF EVENTS THAT RESULTS IN GAS EXCHANGE
GAS EXCHANGE INCLUDES THE FOLLOWING STEPS:
1. VENTILATION: INSPIRATION AND EXPIRATION
2. EXTERNAL RESPIRATION: GAS EXCHANGE BETWEEN AIR IN LUNGS AND
AIR IN BLOOD.
3. INTERNAL RESPIRATION: GAS EXCHANGE BETWEEN BLOOD AND TISSUE
FLUID.
3. CHARACTERISTICS OF RESPIRATORY
SURFACE
1. LARGE SURFACE AREA, IN RELATION TO THE BODY SIZE
2. PERMEABLE, SO THAT GASES CAN PASS THROUGH EASILY
3. THIN WALLS, TO HAVE EFFICIENT DIFFUSION. IT IS ESSENTIAL FOR
EFFECTIVE GAS EXCHANGE
4. A MOIST INNER SURFACE, SO THAT GASES CAN DIFFUSE ACROSS CELL
MEMBRANES
5. RICH BLOOD SUPPLY, TO PROVIDE AN EFFICIENT TRANSPORT SYSTEM TO
MAINTAIN A DIFFUSION GRADIENT.
4. Organs Involved in Gaseous
Exchange.
Nose
Pharynx
Larynx
Trachea
Bronchi
Lungs
6. NOSE
THE NASAL CAVITY OF THE NOSE LEADS TO THE PHARYNX
THE NASAL CAVITY HAS CILIA AND XELLS THAT MAKE MUCUS.
THE MUCUS AND CILIA FILTER THE AIR DUST, POLLEN AND
OTHER FOREIGN PARTICLES
TURBINATE BONES DIVIDE THE NASAL CAVITY IN TO 4 PASSAGES
TO ENLARGE THE SURFACE AREA.
BLOOD VESSELS WARM THE AIR
8. AIR PASSAGES
1. PHARYNX PASS AIR FROM NOSE TO TRACHEA,
VIA LARYNX
2. TRACHEA LONG C-SHAPED CARTILAGE RINGS.
TRACHEA IS LINED WITH CILIA AND GOBLET
CELLS WHICH TRAP FOREIGN PARTICLES
10. BRONCHI AND BRONCHIOLES
TRACHEA DIVIDES IN A RIGHT AND LEFT
BRONCHUS.
BRONCHI BRANCH IN THE LUNGS AND FORM
BRONCHIOLES WHICH BRANCH FURTHER TO FORM
AIR SACS(ALVEOLI), WHICH DO NOT HAVE
CARTILAGE RINGS
14. ALVEOLI
HAS A SINGLE LAYER SQUAMOUS EPITHELIAL CELLS, FOR EASY
DIFFUSION.
SURROUNDED BY NETWORK OF BLOOD CAPILARIES, FOR
TRANSPORTATION
LINED WITH MOIST LAYER OXYGEN DISSOLVES IN THE
MOISTURE AND DIFFUSE INTO BLOOD CAPILARY.
15. PULMONARY DISEASES
PNEUMONIA: Alveoli fill with pus and fluid making gas exchange difficult
PULMONARY FIBROSIS: Fibrous connective tissue builds up in lungs, reducing their
elasticity and Oxygen diffusion.
PULMONARY TUBERCULOSIS: CAUSES BACILLUS BACTERIUM
EMPHYSEMA: ALVEOLI BURST AND DUSE INTO ENLARGED AIR SPACES. REDUCES
SURFACE AREA
BRONCHITIS: AIRWAYS ARE INFLAMED BECAUSE OF INFECTION OR IRRITATION.
ASTHMA: AIRWAYS ARE INFLAMED BECAUSE OF IRRITATION AND BRONCHIOLES
CONSTRICT BECAUSE OF MUSCLE SPASM.
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