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GASTROENTERITIS
Mohammad Ahad Nawaz
Pharm.D 4th Prof
Lahore College of Pharmaceutical Sciences
(UOS)
GASTROENTERITIS
 An infection or inflammation
of the digestive
tract, particularly the
stomach and intestines
 It is frequently referred to as
the stomach or intestinal flu
CAUSES
 Viruses  such as
caliciviruses, rotaviruses, a
stroviruses and
adenoviruses.
CAUSES
 Bacteria  such as
the Campylobacter bacterium
CAUSES
 Parasites  such
as Entamoeba
histolytica, Giardia
lamblia and Cryptosporidium
CAUSES
 Bacterial toxins  poisonous by-
products caused by bacteria can
contaminate food
-Some strains of staphylococcal
bacteria produce toxins that can
cause gastroenteritis
CAUSES
 Chemicals  lead
poisoning, for
example, can trigger
gastroenteritis
CAUSES
 Drugs  certain drugs, such
as antibiotics, can cause
gastroenteritis in susceptible
people and can irritate the
digestive tract
INFECTIOUS GASTROENTERITIS
Escherichia coli infection
 this is a common
problem for travelers
to countries with poor
sanitation. Infection is
caused by drinking
contaminated water
or eating
contaminated raw
fruits and vegetables.
Campylobacter infection
 the bacteria are found in
animal feces. Infection is
caused by, for
example, consuming
contaminated food or
water, eating
undercooked meat
(especially chicken), and
not washing your hands
after handling infected
animals.
INFECTIOUS GASTROENTERITIS
Cryptosporidium infection
 parasites are found in the
bowels of humans and
animals. Infection is caused
by, for example, swimming in
a contaminated pool and
accidentally swallowing
water, or through contact with
infected animals. An infected
person may spread the
parasites to food or surfaces
if they dont wash their hands
after going to the toilet..
Giardiasis
 parasite infection of the
bowel. Infection is caused
by, for example, drinking
contaminated
water, handling infected
animals or changing the
nappy of an infected baby
and not washing your
hands afterwards.
INFECTIOUS GASTROENTERITIS
Salmonellosis
 Bacteria are found in
animal feces. Infection is
caused by eating
contaminated food or
handling infected animals.
An infected person may
also spread the bacteria to
other people or surfaces by
not washing their hands
properly.
Shigellosis
 bacteria are found in
feces. An infected
person may spread
the bacteria to food or
surfaces if they dont
wash their hands after
going to the toilet.
INFECTIOUS GASTROENTERITIS
Viral Gastroenteritis
 viruses are found in human
feces. Infection is caused
by person-to-person
contact such as touching
contaminated hands, feces
or vomit, or by drinking
contaminated water or food.
SYMPTOMS
 Loss of Appetite
 Bloating
SYMPTOMS
 Nausea and Vomiting
 Diarrhea
SYMPTOMS
 Abdominal Pain and
Cramps
 Body Aches
SYMPTOMS
 Bloody stools (in some
cases)
 Pus in the stools (in some
cases)
SYMPTOMS
 Lethargy
 These symptoms are
sometimes also
accompanied by Fever and
Weakness
COMPLICATION
 The greatest danger presented by
gastroenteritis is dehydration. The loss of
fluids through diarrhea and vomiting can
upset the body's electrolyte
balance, leading to potentially life-
threatening problems such as heart beat
abnormalities (arrhythmia)
 The risk of dehydration increases as
symptoms are prolonged. Dehydration
should be suspected if a dry
mouth, increased or excessive thirst, or
scanty urination is experienced
COMPLICATION
 If symptoms do not resolve within a
week, an infection or disorder more
serious than gastroenteritis may be
involved. Symptoms of great concern
include a high fever (102 F [38.9 C] or
above), blood or mucus in the
diarrhea, blood in the vomit, and severe
abdominal pain or swelling. These
symptoms require prompt medical
attention.
DIAGNOSIS
 The symptoms of gastroenteritis are
usually enough to identify the illness
 It is important to establish the cause, as
different types of gastroenteritis respond to
different treatments. Diagnostic methods
may include:
- Medical history
- Physical examination
- Blood tests
- Stool tests
TREATMENT
Treatment depends on the cause
but may include:
 Plenty of fluids and Right Diet
 Oral rehydration
drinks, available from your
chemist
 Admission to hospital and
intravenous fluid
replacement, in severe cases
TREATMENT
 Antibiotics, if bacteria are the cause
 Drugs to kill the parasites, if
parasites are the cause
 Avoiding anti-vomiting or anti-
diarrhea drugs unless prescribed or
recommended by your
doctor, because these medications
will keep the infection inside your
body
PREVENTION
General suggestions on how to reduce the risk of
gastroenteritis include:
 Wash hands thoroughly with soap and
water after going to the toilet or changing
nappies, after smoking, after using a
handkerchief or tissue, or after handling
animals
 Wash your hands thoroughly with soap
and water before preparing food or eating
PREVENTION
 Use disposable paper towels to dry
your hands rather than cloth
towels, since the bacteria can
survive for some time on objects
 Keep cold food cold (below 5 C) and
hot foot hot (above 60 C) to
discourage the growth of bacteria
 Make sure foods are thoroughly
cooked
PREVENTION
 Clean the toilet and bathroom
regularly, especially the toilet
seat, door handles and taps
 When travelling overseas to countries
where sanitation is suspect, only drink
bottled water. Dont forget to brush
your teeth in bottled water too. Avoid
food buffets, uncooked foods or peeled
fruits and vegetables, and ice in drinks
PROGNOSIS
 Gastroenteritis is usually resolved
within 2 to 3 days and there are no
long-term effects. If dehydration
occurs, recovery is extended by a
few days
DISEASE PROCESS
CLINICAL FEATURES OF
GASTROENTERITIS
THANK YOU!!!
By: Katherine L. Laud

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Gastroenteritis

  • 2. Mohammad Ahad Nawaz Pharm.D 4th Prof Lahore College of Pharmaceutical Sciences (UOS)
  • 3. GASTROENTERITIS An infection or inflammation of the digestive tract, particularly the stomach and intestines It is frequently referred to as the stomach or intestinal flu
  • 4. CAUSES Viruses such as caliciviruses, rotaviruses, a stroviruses and adenoviruses.
  • 5. CAUSES Bacteria such as the Campylobacter bacterium
  • 6. CAUSES Parasites such as Entamoeba histolytica, Giardia lamblia and Cryptosporidium
  • 7. CAUSES Bacterial toxins poisonous by- products caused by bacteria can contaminate food -Some strains of staphylococcal bacteria produce toxins that can cause gastroenteritis
  • 8. CAUSES Chemicals lead poisoning, for example, can trigger gastroenteritis
  • 9. CAUSES Drugs certain drugs, such as antibiotics, can cause gastroenteritis in susceptible people and can irritate the digestive tract
  • 10. INFECTIOUS GASTROENTERITIS Escherichia coli infection this is a common problem for travelers to countries with poor sanitation. Infection is caused by drinking contaminated water or eating contaminated raw fruits and vegetables. Campylobacter infection the bacteria are found in animal feces. Infection is caused by, for example, consuming contaminated food or water, eating undercooked meat (especially chicken), and not washing your hands after handling infected animals.
  • 11. INFECTIOUS GASTROENTERITIS Cryptosporidium infection parasites are found in the bowels of humans and animals. Infection is caused by, for example, swimming in a contaminated pool and accidentally swallowing water, or through contact with infected animals. An infected person may spread the parasites to food or surfaces if they dont wash their hands after going to the toilet.. Giardiasis parasite infection of the bowel. Infection is caused by, for example, drinking contaminated water, handling infected animals or changing the nappy of an infected baby and not washing your hands afterwards.
  • 12. INFECTIOUS GASTROENTERITIS Salmonellosis Bacteria are found in animal feces. Infection is caused by eating contaminated food or handling infected animals. An infected person may also spread the bacteria to other people or surfaces by not washing their hands properly. Shigellosis bacteria are found in feces. An infected person may spread the bacteria to food or surfaces if they dont wash their hands after going to the toilet.
  • 13. INFECTIOUS GASTROENTERITIS Viral Gastroenteritis viruses are found in human feces. Infection is caused by person-to-person contact such as touching contaminated hands, feces or vomit, or by drinking contaminated water or food.
  • 14. SYMPTOMS Loss of Appetite Bloating
  • 15. SYMPTOMS Nausea and Vomiting Diarrhea
  • 16. SYMPTOMS Abdominal Pain and Cramps Body Aches
  • 17. SYMPTOMS Bloody stools (in some cases) Pus in the stools (in some cases)
  • 18. SYMPTOMS Lethargy These symptoms are sometimes also accompanied by Fever and Weakness
  • 19. COMPLICATION The greatest danger presented by gastroenteritis is dehydration. The loss of fluids through diarrhea and vomiting can upset the body's electrolyte balance, leading to potentially life- threatening problems such as heart beat abnormalities (arrhythmia) The risk of dehydration increases as symptoms are prolonged. Dehydration should be suspected if a dry mouth, increased or excessive thirst, or scanty urination is experienced
  • 20. COMPLICATION If symptoms do not resolve within a week, an infection or disorder more serious than gastroenteritis may be involved. Symptoms of great concern include a high fever (102 F [38.9 C] or above), blood or mucus in the diarrhea, blood in the vomit, and severe abdominal pain or swelling. These symptoms require prompt medical attention.
  • 21. DIAGNOSIS The symptoms of gastroenteritis are usually enough to identify the illness It is important to establish the cause, as different types of gastroenteritis respond to different treatments. Diagnostic methods may include: - Medical history - Physical examination - Blood tests - Stool tests
  • 22. TREATMENT Treatment depends on the cause but may include: Plenty of fluids and Right Diet Oral rehydration drinks, available from your chemist Admission to hospital and intravenous fluid replacement, in severe cases
  • 23. TREATMENT Antibiotics, if bacteria are the cause Drugs to kill the parasites, if parasites are the cause Avoiding anti-vomiting or anti- diarrhea drugs unless prescribed or recommended by your doctor, because these medications will keep the infection inside your body
  • 24. PREVENTION General suggestions on how to reduce the risk of gastroenteritis include: Wash hands thoroughly with soap and water after going to the toilet or changing nappies, after smoking, after using a handkerchief or tissue, or after handling animals Wash your hands thoroughly with soap and water before preparing food or eating
  • 25. PREVENTION Use disposable paper towels to dry your hands rather than cloth towels, since the bacteria can survive for some time on objects Keep cold food cold (below 5 C) and hot foot hot (above 60 C) to discourage the growth of bacteria Make sure foods are thoroughly cooked
  • 26. PREVENTION Clean the toilet and bathroom regularly, especially the toilet seat, door handles and taps When travelling overseas to countries where sanitation is suspect, only drink bottled water. Dont forget to brush your teeth in bottled water too. Avoid food buffets, uncooked foods or peeled fruits and vegetables, and ice in drinks
  • 27. PROGNOSIS Gastroenteritis is usually resolved within 2 to 3 days and there are no long-term effects. If dehydration occurs, recovery is extended by a few days