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Genscript Overview

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Qian (Nicole) Niu
Qian (Nicole) Niu

GenScript is a biotechnology company founded in 2002 that provides gene synthesis, protein and antibody services. It has over 800 employees across facilities in the US, China, France and Japan. GenScript is the largest provider of custom gene synthesis in the US and offers services including gene synthesis, cloning, mutagenesis, and plasmid preparation. It also provides protein and antibody services such as expression, purification, production and development of monoclonal and polyclonal antibodies. GenScript focuses on intellectual property protection and being a reliable partner for its pharmaceutical and biotech clients.

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March 2010 Introducing GenScript
Presentation Overview 1 2 3 4 The Biology CRO About GenScript Service Overview Your Reliable Partner
About GenScript Founded in 2002 >800 employees Headquarters in Piscataway, NJ, USA Facilities and branches: New Jersey, USA Nanjing, China Paris, France Osaka, Japan
Fast Growing Company Organic Growth Since Inception 2002 2003 2004 2005 2006 2007 2008
The largest provider of custom gene synthesis services in the U.S. We offer the best antibody service guarantee in the industry We provide small- and large-molecule one-stop biology CRO services for early drug discovery and development Local access and 24-hour customer support ISO 9001:2000-certified and full client IP protection We offer advanced bioinformatics tools and IT infrastructure for value-added services Customers include top pharmaceutical companies, major biotech firms, and research institutions in over 70 countries Seasoned science and business management teams Key Facts About GenScript
INVESTORS Most respected VC in the world Funded Genentech, Google, Amazon, Pacific Biosciences, etc Invested in > 300 IT , life science, and biotech companies Leading independent advisory company Top boutique investment banking firm in China Clients include Sinopec, Jiangsu Lihua, Masterrind, Medical Systems In Search of the Next Big Idea
Comprehensive Biology Services
Transforming Molecular Biology Gene Synthesis Any gene you desire! Synthesize genes OptimumGene TM Codon Optimization Large-Scale Gene Synthesis Cloning Any construct you want to build! PCR Cloning/Subcloning GenPool TM ORF Cloning KI & KO Vector Construction Custom vector construction Mutagenesis Any variant from your design! Mutagenesis Service Site-Directed Mutagenesis Libraries Sequential Permutation Scanning Libraries Randomized and Degenerated Libraries Plasmid Preparation Any amount to fit your plan! Flexible Scale: 100 亮g to 1,000 mg Low Endotoxin Levels: <5 EU/mg Largest Gene Synthesis Supplier in USA
GenScript One Stop Protein Services Gene Services Largest gene synthesis supplier in US Comprehensive portfolio of molecular biology services: Codon Optimization Cloning Vector Construction Mutagenesis Plasmid Preparation etc. Protein Services Expression (E.coli, yeast, insect, mammalian) Purification Production of biologically functional protein Large capacity for scale-up (fermentation, protein production from stable cell lines) Antibody Services pAb production mAb production Hybridoma development Assay Services Assay development & validation (GPCR, ion channel, enzyme) Compound screening & profiling
Custom Peptide Synthesis Services Custom Peptide Synthesis Services Non-GMP Peptides GMP Peptides Standard Peptide Synthesis High complexity and purity Long peptides up to 200 aa High success rate 95% Peptide Libraries Rapid parallel platform Competitive prices Guaranteed delivery Flexible screening tools Cosmetic Peptides FlexPeptide TM technology Comprehensive documents Batch size from mg to 2 kg Peptides up to 50 aa Recombinant Peptides Flexible technology Variety of modifications Any length, any sequence, any scale
Guaranteed Antibody Services Custom pAb and mAb Services Catalog antibodies Express services Best guaranty in the industry pAb Services Affinity-Purified pAb Phospho-Specific pAb Express Antibody TM Services Species: rabbit, goat/sheep, chicken, mouse, rat, etc mAb services MonoExpress TM Antibody Services mAb Production Services Most Popular: Phospho-Specific pAb Package Large Scale Antibody Production Services Additional Services Ab Modification Ab Purification Ab Characterization Cell Line Storage Peptide Synthesis Services Immunoassay Development Services for Drug Discovery & Clinical Studies Leading the industry standard on antibody guarantee
In house Project Design Antibody Affinity Maturation Stable Cell Line Generation Antibody Production Bioprocess Development Target Validation Industry-scale Antibody Drug Development Immunon-ization Hybridoma Selection Maturation Production Target Validation Antibody Drug Development Center
Antibody Drug Development Center Protein Antigen production Molecular Biology Library construction mAb sequencing Antibody Engineering Affinity maturation Antibody humanization Anti-idiotype antibody generation Epitopic mapping Antibody Production Hybridoma Protein purification Bioprocess Development Transient and stable expression in flexible scales Comprehensive Antibody Drug Development
Transient Gene Expression and Protein Production Proprietary technology Serum free 293 and CHO suspension systems Rapid protein and mAb production up to grams Stable Cell Line Development and Protein Production Proprietary expression system High flexibility with parental cell types State-of-the-Art facilities Record proven on-time delivery Process Development and Transfer We pay attention to every single detail BioProcess Services Stable cell development Bioreactors and WAVE-bag technology Industry Scale Protein Production Custom Solution Bioprocess Services
Our Innovation Innovative technologies for enhanced services Gene-on-Demand TM gene synthesis technology - best and most economic gene synthesis FlexChem TM ligation technology - peptide synthesis up to 200 amino acids CloneEZ TM seamless cloning technology - state-of-art cloning into any vector at any site Nanotechnology for adjuvant mixing - induction of enhanced immune response Diversified expression systems - bacteria, yeast, insect cells, and mammalian cells T-Max TM adjuvant - increased titer of at least ten times, and reduced cost FoldingArt TM technology - refold rate of 95% for inclusion bodies and proteins (virus expression) OptimumAntigen TM antigen design - optimized antigen design 293TGE TM system - most efficient transient expression system OptimumGene TM codon optimization technology - optimized gene expression
YOUR RELIABLE PARTNER
Business Model Your Reliable Partner
Confidentiality agreement for each contract project Secure online information transfer Account specific document management Strict access control for dedicated research areas Client Client Your Reliable Partner IP protection is crucial to a sustainable partnership between pharmaceutical clients and GenScript
Thank you! Your Innovation Partner in Drug Discovery! Nicole Niu, Ph.D. Regional Sales Manager GenScript USA Inc. 120 Centennial Ave, Piscataway, NJ 08854, USA Tel: 732-885-9188 x 155 Fax: 732-210-0262 Email: [email_address]

More Related Content

Genscript Overview

  • 1. March 2010 Introducing GenScript
  • 2. Presentation Overview 1 2 3 4 The Biology CRO About GenScript Service Overview Your Reliable Partner
  • 3. About GenScript Founded in 2002 >800 employees Headquarters in Piscataway, NJ, USA Facilities and branches: New Jersey, USA Nanjing, China Paris, France Osaka, Japan
  • 4. Fast Growing Company Organic Growth Since Inception 2002 2003 2004 2005 2006 2007 2008
  • 5. The largest provider of custom gene synthesis services in the U.S. We offer the best antibody service guarantee in the industry We provide small- and large-molecule one-stop biology CRO services for early drug discovery and development Local access and 24-hour customer support ISO 9001:2000-certified and full client IP protection We offer advanced bioinformatics tools and IT infrastructure for value-added services Customers include top pharmaceutical companies, major biotech firms, and research institutions in over 70 countries Seasoned science and business management teams Key Facts About GenScript
  • 6. INVESTORS Most respected VC in the world Funded Genentech, Google, Amazon, Pacific Biosciences, etc Invested in > 300 IT , life science, and biotech companies Leading independent advisory company Top boutique investment banking firm in China Clients include Sinopec, Jiangsu Lihua, Masterrind, Medical Systems In Search of the Next Big Idea
  • 8. Transforming Molecular Biology Gene Synthesis Any gene you desire! Synthesize genes OptimumGene TM Codon Optimization Large-Scale Gene Synthesis Cloning Any construct you want to build! PCR Cloning/Subcloning GenPool TM ORF Cloning KI & KO Vector Construction Custom vector construction Mutagenesis Any variant from your design! Mutagenesis Service Site-Directed Mutagenesis Libraries Sequential Permutation Scanning Libraries Randomized and Degenerated Libraries Plasmid Preparation Any amount to fit your plan! Flexible Scale: 100 亮g to 1,000 mg Low Endotoxin Levels: <5 EU/mg Largest Gene Synthesis Supplier in USA
  • 9. GenScript One Stop Protein Services Gene Services Largest gene synthesis supplier in US Comprehensive portfolio of molecular biology services: Codon Optimization Cloning Vector Construction Mutagenesis Plasmid Preparation etc. Protein Services Expression (E.coli, yeast, insect, mammalian) Purification Production of biologically functional protein Large capacity for scale-up (fermentation, protein production from stable cell lines) Antibody Services pAb production mAb production Hybridoma development Assay Services Assay development & validation (GPCR, ion channel, enzyme) Compound screening & profiling
  • 10. Custom Peptide Synthesis Services Custom Peptide Synthesis Services Non-GMP Peptides GMP Peptides Standard Peptide Synthesis High complexity and purity Long peptides up to 200 aa High success rate 95% Peptide Libraries Rapid parallel platform Competitive prices Guaranteed delivery Flexible screening tools Cosmetic Peptides FlexPeptide TM technology Comprehensive documents Batch size from mg to 2 kg Peptides up to 50 aa Recombinant Peptides Flexible technology Variety of modifications Any length, any sequence, any scale
  • 11. Guaranteed Antibody Services Custom pAb and mAb Services Catalog antibodies Express services Best guaranty in the industry pAb Services Affinity-Purified pAb Phospho-Specific pAb Express Antibody TM Services Species: rabbit, goat/sheep, chicken, mouse, rat, etc mAb services MonoExpress TM Antibody Services mAb Production Services Most Popular: Phospho-Specific pAb Package Large Scale Antibody Production Services Additional Services Ab Modification Ab Purification Ab Characterization Cell Line Storage Peptide Synthesis Services Immunoassay Development Services for Drug Discovery & Clinical Studies Leading the industry standard on antibody guarantee
  • 12. In house Project Design Antibody Affinity Maturation Stable Cell Line Generation Antibody Production Bioprocess Development Target Validation Industry-scale Antibody Drug Development Immunon-ization Hybridoma Selection Maturation Production Target Validation Antibody Drug Development Center
  • 13. Antibody Drug Development Center Protein Antigen production Molecular Biology Library construction mAb sequencing Antibody Engineering Affinity maturation Antibody humanization Anti-idiotype antibody generation Epitopic mapping Antibody Production Hybridoma Protein purification Bioprocess Development Transient and stable expression in flexible scales Comprehensive Antibody Drug Development
  • 14. Transient Gene Expression and Protein Production Proprietary technology Serum free 293 and CHO suspension systems Rapid protein and mAb production up to grams Stable Cell Line Development and Protein Production Proprietary expression system High flexibility with parental cell types State-of-the-Art facilities Record proven on-time delivery Process Development and Transfer We pay attention to every single detail BioProcess Services Stable cell development Bioreactors and WAVE-bag technology Industry Scale Protein Production Custom Solution Bioprocess Services
  • 15. Our Innovation Innovative technologies for enhanced services Gene-on-Demand TM gene synthesis technology - best and most economic gene synthesis FlexChem TM ligation technology - peptide synthesis up to 200 amino acids CloneEZ TM seamless cloning technology - state-of-art cloning into any vector at any site Nanotechnology for adjuvant mixing - induction of enhanced immune response Diversified expression systems - bacteria, yeast, insect cells, and mammalian cells T-Max TM adjuvant - increased titer of at least ten times, and reduced cost FoldingArt TM technology - refold rate of 95% for inclusion bodies and proteins (virus expression) OptimumAntigen TM antigen design - optimized antigen design 293TGE TM system - most efficient transient expression system OptimumGene TM codon optimization technology - optimized gene expression
  • 17. Business Model Your Reliable Partner
  • 18. Confidentiality agreement for each contract project Secure online information transfer Account specific document management Strict access control for dedicated research areas Client Client Your Reliable Partner IP protection is crucial to a sustainable partnership between pharmaceutical clients and GenScript
  • 19. Thank you! Your Innovation Partner in Drug Discovery! Nicole Niu, Ph.D. Regional Sales Manager GenScript USA Inc. 120 Centennial Ave, Piscataway, NJ 08854, USA Tel: 732-885-9188 x 155 Fax: 732-210-0262 Email: [email_address]