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her
Assistant prof .DR. Adnan m.jasim
AL-Qasim green university/college of
veterinary medicine
herbicide
Any chemical compounds that have potential of either killing or
damaging unwanted plants or weeds for elimination such plant
, that depend on biochemical difference in plants, that act
selectively for some plants. In early old days (sulfuric acide ,
aresenic tetroxide and petroleum oil etc ) used but not selective
activity.
Herbicide classification
 Dinitro compound
(DNOC).
 Phenoxyacetic acid e.g
2,4-D.
 Bipyridinum compound
 1-diquate
 2-Paraquate
 Triazene
 1- atrazine
 Substituted urease
 1-monouron
 2-diurone
DNOC
 Source of poisoning
 Accidental ingestion of DNOC
 licking empty dnoc container by animal
 MECHANISM OF TOXICITY
 Interfering with electron transport chain energy
metabolism .they uncoupled oxidative
phosphorylation convert all cellular energy to heat
sever hyperthermia . In ruminant DNOC convert to
diamine that induce methaemoglobinurea .
Differential diagnosis AND
TREATMENT
 Heat strock
 nitrate (chocolate coloured blood , no heating .poisoning with
carbone monoxiide , no pyrexia .
 TREATMENT STRATIGIES
 washing animal with water and placed in cold weather .2-
antipyretics (paracetamol).
 saline purgatives
 Dextrose saline
 Diazepam as sedative .
 Ascorbic acid and methylene blue
Phenoxy acetic acid
 Dichlorophenoxyacetic acid and dichlorophenoxyacetic acid
 Hormones are plant hormone regulator act selecively against dicotyledone
 Mechanism of toxicity : produce reproductive toxicity in cattle and hepato
carcinoma in lab animal.
 Clinical signs: anorexia , diarrhea , abortion ,irregular estrus , anestrus , and
atrophy of ovarian .
 Treatment :
 No specific antidote
 Treatment syptomatic and supportive therapy according syptoms .
BIPYRIDINUM COMPOUND
 are highly toxic compound
 Used in agriculture of cotton , potatoes ,weeds control. heat stable
about 300C.
 MECHANISM OF ACTION
 Corrosive and irritant to skin as well as cause irreversible pulmonary
fibrosis.
 After inhalation lead to generative oxidative stress hydrogen
peroxid and superoxide anion can attack unsaturated lipids.
 Differential diagnosis
 -bovine pulmonary odema
 Pnemonia
Treatment
 The is no specific antidote given supptomatic
 Emetic or gastric lavage if acute ingested ,
antacid as well as diuretics.
 Tranqulizer and sedative
 Vitiamines specially C and E
 non steroid ant inflammator
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Herbicide

  • 1. her Assistant prof .DR. Adnan m.jasim AL-Qasim green university/college of veterinary medicine
  • 2. herbicide Any chemical compounds that have potential of either killing or damaging unwanted plants or weeds for elimination such plant , that depend on biochemical difference in plants, that act selectively for some plants. In early old days (sulfuric acide , aresenic tetroxide and petroleum oil etc ) used but not selective activity.
  • 3. Herbicide classification Dinitro compound (DNOC). Phenoxyacetic acid e.g 2,4-D. Bipyridinum compound 1-diquate 2-Paraquate Triazene 1- atrazine Substituted urease 1-monouron 2-diurone
  • 4. DNOC Source of poisoning Accidental ingestion of DNOC licking empty dnoc container by animal MECHANISM OF TOXICITY Interfering with electron transport chain energy metabolism .they uncoupled oxidative phosphorylation convert all cellular energy to heat sever hyperthermia . In ruminant DNOC convert to diamine that induce methaemoglobinurea .
  • 5. Differential diagnosis AND TREATMENT Heat strock nitrate (chocolate coloured blood , no heating .poisoning with carbone monoxiide , no pyrexia . TREATMENT STRATIGIES washing animal with water and placed in cold weather .2- antipyretics (paracetamol). saline purgatives Dextrose saline Diazepam as sedative . Ascorbic acid and methylene blue
  • 6. Phenoxy acetic acid Dichlorophenoxyacetic acid and dichlorophenoxyacetic acid Hormones are plant hormone regulator act selecively against dicotyledone Mechanism of toxicity : produce reproductive toxicity in cattle and hepato carcinoma in lab animal. Clinical signs: anorexia , diarrhea , abortion ,irregular estrus , anestrus , and atrophy of ovarian . Treatment : No specific antidote Treatment syptomatic and supportive therapy according syptoms .
  • 7. BIPYRIDINUM COMPOUND are highly toxic compound Used in agriculture of cotton , potatoes ,weeds control. heat stable about 300C. MECHANISM OF ACTION Corrosive and irritant to skin as well as cause irreversible pulmonary fibrosis. After inhalation lead to generative oxidative stress hydrogen peroxid and superoxide anion can attack unsaturated lipids. Differential diagnosis -bovine pulmonary odema Pnemonia
  • 8. Treatment The is no specific antidote given supptomatic Emetic or gastric lavage if acute ingested , antacid as well as diuretics. Tranqulizer and sedative Vitiamines specially C and E non steroid ant inflammator