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Hormone replacement therapy & potassium supplements pptx

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This document presents information from Himanshu Dhiran's presentation on hormone replacement therapy and potassium supplements. It discusses how HRT can help balance hormone levels during menopause and relieve symptoms. It outlines the types of hormones involved in HRT and benefits like reduced bone loss and cancer risk, as well as risks including certain cancers and blood clots. The document also discusses potassium's role in the body, its use as a supplement for hypokalemia, potential benefits for blood pressure and stroke, dosing guidelines, and natural food sources of potassium.

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NAME- HIMANSHU DHIRAN M.PHARM ( DRA ) Roll No- 18/MRA/SPS/2021 Facilitated by – Dr. Sharmishtha Dept. – Drug Regulatory Affairs. Delhi Pharmaceutical Sciences & Research University . Presented by – Himanshu Dhiran Roll No- 18/MRA/SPS/2021 1st M. Pharm, Drug Regulatory Affairs.
INTRODUCTION Hormone replacement therapy (HRT) can help balance estrogen and progesterone levels during or near menopause. There are also many other reasons why a doctor might prescribe supplementary sex hormones. Also known as menopausal hormone therapy, HRT can help relieve sweating, hot flashes, and other symptoms of menopause.
Hormones are … Powerful chemical messengers. Derived from cholesterol. Made in the brain, ovaries, testicles, adrenal glands, and body fats. Affects every tissues in the body.
Types of HRT… Human growth hormone (HGH). Melatonin (pineal hormone). T3 and T4 (thyroid hormones). Estrogen (female sex hormone). Progesterone (female sex hormone). Testosterone (male and female sex hormone).
Benefits of HRT… Improvement of vasomotor symptoms (70- 80%). Increase in bone mineral density (2-5%). Decreased risk in vertebral and hip fractures(25-50%). Reduction in colorectal cancer (20%)Possibly cardio protection.
Risks of HRT… Endometrial Cancer. Breast Cancer. Venous Thromboembolic Disease (VTE). Coronary Heart Disease (CHD). Lipid Metabolism.
Duration of HRT use… Generally, use of HRT for a short period of 3-5 years have been advised. Reduction of dosage should be done as soon as possible. Menopausal women should maintain optimum nutrition, ideal body weight and perform regular exercise.
Contraindication of HRT… Undiagnosed genital tract bleeding.  Estrogen dependent neoplasm in the body. History of venous thromboembolism Active liver disease. Gallbladder disease. Known, Suspected or history of Breast cancer.
POTASSIUM Potassium is a mineral that is important for many body functions. Food sources include fruits, cereals, beans, milk, and vegetables. Potassium plays a role in the transmission of nerve signals, muscle contractions, fluid balance, and various chemical reactions.
POTASSIUM SUPPLEMENT potassium supplements may be needed by patients who do not have enough potassium in their regular diet or have lost too much potassium because of illness or treatment with certain medicines.
Uses & Effectiveness EFFECTIVE FOR – Low levels of potassium in the blood (hypokalemia). Taking potassium by mouth or by IV prevents and treats low levels of potassium in the blood. IV product scan only be given by a healthcare provider.
Uses & Effectiveness Likely Effective for- High blood pressure. Taking potassium can lower blood pressure. Potassium seems to work best for people with high blood pressure. Possibly Effective for- Stroke. Higher intake of potassium from food has been linked to up to a 20%reduced risk of stroke.
Special Precautions and Warnings Pregnancy and breast-feeding. Disorders of the digestive tract. Kidney disease.
DOSING… It's recommended that adult females consume 2.6 grams daily, and adult males consume 3.4 grams daily to maintain adequate nutrition. When pregnant, 2.9grams should be consumed daily, and when breastfeeding, 2.8 grams should be consumed daily, Recommended amounts for children depend on age.
Natural Source of Potassium… Bananas. Avocados. Peanuts and tree nuts such as almonds, pecans and walnuts. Citrus fruits. Leafy, green vegetables. Milk.
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Hormone replacement therapy & potassium supplements pptx

  • 1. NAME- HIMANSHU DHIRAN M.PHARM ( DRA ) Roll No- 18/MRA/SPS/2021 Facilitated by – Dr. Sharmishtha Dept. – Drug Regulatory Affairs. Delhi Pharmaceutical Sciences & Research University . Presented by – Himanshu Dhiran Roll No- 18/MRA/SPS/2021 1st M. Pharm, Drug Regulatory Affairs.
  • 2. INTRODUCTION Hormone replacement therapy (HRT) can help balance estrogen and progesterone levels during or near menopause. There are also many other reasons why a doctor might prescribe supplementary sex hormones. Also known as menopausal hormone therapy, HRT can help relieve sweating, hot flashes, and other symptoms of menopause.
  • 3. Hormones are … Powerful chemical messengers. Derived from cholesterol. Made in the brain, ovaries, testicles, adrenal glands, and body fats. Affects every tissues in the body.
  • 4. Types of HRT… Human growth hormone (HGH). Melatonin (pineal hormone). T3 and T4 (thyroid hormones). Estrogen (female sex hormone). Progesterone (female sex hormone). Testosterone (male and female sex hormone).
  • 5. Benefits of HRT… Improvement of vasomotor symptoms (70- 80%). Increase in bone mineral density (2-5%). Decreased risk in vertebral and hip fractures(25-50%). Reduction in colorectal cancer (20%)Possibly cardio protection.
  • 6. Risks of HRT… Endometrial Cancer. Breast Cancer. Venous Thromboembolic Disease (VTE). Coronary Heart Disease (CHD). Lipid Metabolism.
  • 7. Duration of HRT use… Generally, use of HRT for a short period of 3-5 years have been advised. Reduction of dosage should be done as soon as possible. Menopausal women should maintain optimum nutrition, ideal body weight and perform regular exercise.
  • 8. Contraindication of HRT… Undiagnosed genital tract bleeding.  Estrogen dependent neoplasm in the body. History of venous thromboembolism Active liver disease. Gallbladder disease. Known, Suspected or history of Breast cancer.
  • 9. POTASSIUM Potassium is a mineral that is important for many body functions. Food sources include fruits, cereals, beans, milk, and vegetables. Potassium plays a role in the transmission of nerve signals, muscle contractions, fluid balance, and various chemical reactions.
  • 10. POTASSIUM SUPPLEMENT potassium supplements may be needed by patients who do not have enough potassium in their regular diet or have lost too much potassium because of illness or treatment with certain medicines.
  • 11. Uses & Effectiveness EFFECTIVE FOR – Low levels of potassium in the blood (hypokalemia). Taking potassium by mouth or by IV prevents and treats low levels of potassium in the blood. IV product scan only be given by a healthcare provider.
  • 12. Uses & Effectiveness Likely Effective for- High blood pressure. Taking potassium can lower blood pressure. Potassium seems to work best for people with high blood pressure. Possibly Effective for- Stroke. Higher intake of potassium from food has been linked to up to a 20%reduced risk of stroke.
  • 13. Special Precautions and Warnings Pregnancy and breast-feeding. Disorders of the digestive tract. Kidney disease.
  • 14. DOSING… It's recommended that adult females consume 2.6 grams daily, and adult males consume 3.4 grams daily to maintain adequate nutrition. When pregnant, 2.9grams should be consumed daily, and when breastfeeding, 2.8 grams should be consumed daily, Recommended amounts for children depend on age.
  • 15. Natural Source of Potassium… Bananas. Avocados. Peanuts and tree nuts such as almonds, pecans and walnuts. Citrus fruits. Leafy, green vegetables. Milk.