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Potent plants
for
Hypothyroidism
(Part  II)
Presented by
Dr. Sudhakar Kokate
Director PPRC, India
Allopathic medications
 Levothroid
 Levoxyl
 Synthroid
PPRC/INDIA 01
 Cytomel
 Euthroid
 Thyrolar
Side effects
PPRC/INDIA 02
 Tremors
 Nervousness
 Heart palpitation
 Too much weight loss
 Bone thinning
 Frequent bowel movements
Scientific investigations
PPRC/INDIA 03
Scientific investigations on thyroid dependent respiration,
cardiovascular system, digestion neural regulation and
reproduction
 Investigations were started few years back
 Herbal regulation of thyroid function is recent concept and
acquiring attention of scientists worldwide
Scientific investigations
PPRC/INDIA 04
 Commercial Ayurvedic drugs are also available in market
due to intense efforts of scientists
 Research work on possible mode of action of plants is in
progress
 Different plant products appears to be different in different
plant extracts
Scientific investigations
PPRC/INDIA 05
 Dose dependent activity is observed in experiments about
thyroid-plant relationship
 In general herbal products are safe
 Some plant extracts in combination with other improve
quality
 Standardization of dose and duration needed
Plant derived drugs for hypothyroidism
PPRC/INDIA 06
 Suddha guggulu
 Kanchnar guggulu
 Gayatrin
 Kelp
 Ginseng
 Wulong dan
 Fuschen decoction
 Liv. 52
Achyranthes aspera
PPRC/INDIA 07
Achyranthes aspera
PPRC/INDIA 08
 Dose: 200 mg / kg
 Days treated: 7
 Ref: Tahiliani and Kar 2000
Bacopa monnieri
PPRC/INDIA 09
Bacopa monnieri
PPRC/INDIA 10
 Dose: 200 mg / kg
 Days treated: 15
 Ref: Kar et. al. 2002
Bauhinia variegata
PPRC/INDIA 11
Bauhinia variegata
PPRC/INDIA 12
 Dose: 200 mg / kg
 Days treated: 20
 Ref: Veena et. al. 1975
Bauhinia purpurea
PPRC/INDIA 13
Bauhinia purpurea
PPRC/INDIA 14
 Dose: 2.5 mg / kg
 Days treated: 20
 Ref: Panda and Kar 1999, 2000
Commiphora mukul
PPRC/INDIA 15
Commiphora mukul
PPRC/INDIA 16
 Dose: 200 mg / kg
 Days treated: 15
 Ref: Panda and Kar 1998
Veena et. al. 1975
Eichorina crassipes
PPRC/INDIA 17
Eichorina crassipes
PPRC/INDIA 18
 Dose: 200 mg / kg
 Days treated: 20
 Ref: Veena et. al. 1975
Inula racemosa
PPRC/INDIA 19
Inula racemosa
PPRC/INDIA 20
 Dose: 400 mg / kg
 Days treated: 21
 Ref: Tripathi and Chaturvedi 1995
Momordica charantia
PPRC/INDIA 21
Momordica charantia
PPRC/INDIA 22
 Dose: 200 mg / kg
 Days treated: 15
 Ref: Panda and Kar 2000
Piper betle
PPRC/INDIA 23
Piper betle
PPRC/INDIA 24
 Dose: 400 mg / kg
 Days treated: 15
 Ref: Panda and Kar 2000
Sida cordifolia
PPRC/INDIA 25
Sida cordifolia
PPRC/INDIA 26
 Dose: 100 mg / kg
 Days treated: 15
 Ref: Tahiliani and Kar 2001
Saussurea lappa
PPRC/INDIA 27
Saussurea lappa
PPRC/INDIA 28
 Dose: 400 mg / kg
 Days treated: 14
 Ref: Chaturvedi et. al. 1993
Withania somnifera
PPRC/INDIA 29
Withania somnifera
PPRC/INDIA 30
 Dose: 1400 mg / kg
 Days treated: 30
 Ref: Panda and Kar 1998, 1999
Thank You !!
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