1. The document presents results from toxicity tests of secondary metabolite extracts from the mushroom Clitocybe nuda. 2. Cytotoxicity assays in Balb/c3T3 and HepG2 cells found the estimated acute oral toxicity LD50 to be above 2000 mg/kg, indicating non-acute oral toxicity. 3. Mutagenicity and genotoxicity assays including bacterial reverse mutation and in vitro micronucleus tests showed clear negative results, demonstrating the extract is non-genotoxic.