Capnography measures exhaled carbon dioxide (CO2) through either colorimetric or waveform methods. It can be used to confirm endotracheal tube placement, monitor cardiac and pulmonary physiology, guide resuscitation, and detect hypoventilation earlier than pulse oximetry alone. Specific capnography waveforms and values provide information about cardiac output, airway obstruction, lung disease, and response to CPR.
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ICU_one_pager_end_tidal_co2.pptx
1. EXHALATION INHALATION
SpO2
98
PI
0.8
by Nick Mark MD
CAPNOGRAPHY onepageric
u.com
@nickmma
rk
Link to the
most current
version
ONE
COLORIMETRIC CAPNOGRAPH
CC
BY-SA
3.0
v1.1
(2020-11-18)
Measurement of exhaled carbon dioxide can be used to confirm
ETT placement, for safer procedural sedation, to guide
resuscitation, and to monitor cardiac & pulmonary physiology.
揃 PETCO2 End-tidal CO2 (whats measured by capnography)
揃 PACO2 Alveolar CO2
揃 PvCO2 Mixed venous CO2
揃 PaCO2 Arterial CO2 (whats measured on an ABG)
PETCO2 is usually less than PaCO2 because of dead space. If
physiological dead space increases the difference between
PETCO2 and PaCO2 will also rise. Examples include:
揃 Low cardiac output reduced delivery of CO2 to lungs
揃 Blockage of Pulmonary arteries (pulmonary embolus)
PRINCIPLE:
PaCO2
PvCO2
PACO2
PETCO2
45
35
40
40
ETCO2 IN CARDIAC ARREST
ETT CONFIRMATION
Litmus paper changes color based on pH;
exhaled CO2 lowers the pH and causes the the
paper to transiently turn from PURPLE to
YELLOW (MELLOW YELLOW); acidic vomitus can
cause a false permanent color change.
A
B
C
Provides an approximate
PETCO2 reading as each
area is sensitive to
different ETCO2 values:
A <4 MMHG
B 4-15 MMHG
C 15-38 MMHG
39
14
ETCO2
RR
PORTABLE ELECTRONIC CAPNOGRAPH WAVEFORM CAPNOGRAPH
ETCO2
(mmHg)
0
10
20
30
40
50
etCO2
39
RR
14
Side-stream detector
(LONGER LATENCY)
I
II
III
IV
The waveform is composed of 4 phases
揃 Phase I anatomical dead space ventilation
揃 Phase II dead space mixed with alveolar ventilation
揃 Phase III alveolar ventilation (where ETCO2 measured)
揃 Phase IV end of exhalation
CAPNOGRAPH WAVEFORM :
ETCO2 IN PROCEDURAL SEDATION
Measured PETCO2
IR spectroscopy precisely
measures exhaled CO2 content
IR spectroscopy measures exhaled CO2
content and displays results graphically;
can also be used with special nasal
cannula to monitor non-intubated pts.
PROLONGED PHASE II/III 揃 Bronchospasm
揃 Airway obstruction
揃 COPD
CARDIAC OSCILLATIONS 揃 Hypovolemia
揃 Hypoventilation
CURARE CLEFT 揃 Patient dysynchrony
during mechanical
ventilation breath
DIMORPHIC PHASE II/II
揃 Right mainstem intubation
揃 Differential lung emptying
(Single lung transplant, severe
kyphoscoliosis, etc)
PROMINENT PHASE IV 揃 Obesity
揃 Pregnancy
揃 Poor compliance
SUDDEN DROP IN ETCO2 揃 Displaced ETT
揃 Decreased CO (arrythmia, PE, etc)
Adequacy of CPR
揃 Achieving an PETCO2 > 20mmHg is
associated with adequate CPR. If not
achieving this goal consider rotating the
person performing compressions.
Detection of ROSC
揃 Sudden increase in PETCO2 during CPR
is a marker for ROSC.
Determination of futility
揃 Persistent PETCO2 < 10 for > 20 min is
associated with futility, and even 5 min
with ETCO2 < 10 is associated with poor
outcomes.
Confirmation of exhaled CO2 can be used for
ETT placement confirmation. Colorimetric
capnograph is only appropriate in well
perfusing patients; waveform capnograph is
more accurate, particularly in low CO states.
SPECIFIC CAPNOGRAPH PATTERNS:
shark fin
Waveform capnography can be used to
monitor for hypoventilation in non-intubated
patients during procedural sedation (using an
ETCO2 sensor nasal cannula). Waveform
capnography is more sensitive than just SpO2
monitoring, and can detect hypoventilation
up to 60 seconds before desaturation occurs.
揃 Poor gas exchange due to overdistension of alveoli high TV, excessive PEEP, COPD
ETCO2 waveform Peak ETCO2 value
Each heartbeat ejects a
small amount of CO2
Terminal
upswing
DOWNSLOPING PHASE III
揃 Severe emphysema
(alveoli destruction can cause
rapid initial emptying of CO2)
Mainstream
(in-line)
detector
(SHORTER
LATENCY)
2. EXHALATION INHALATION
SpO2
98
PI
0.8
by Nick Mark MD
CAPNOGRAPHY onepageric
u.com
@nickmma
rk
Link to the
most current
version
ONE
COLORIMETRIC CAPNOGRAPH
Measurement of exhaled carbon dioxide can be used to confirm
ETT placement, for safer procedural sedation, to guide
resuscitation, and to monitor cardiac & pulmonary physiology.
揃 PETCO2 End-tidal CO2 (whats measured by capnography)
揃 PACO2 Alveolar CO2
揃 PvCO2 Mixed venous CO2
揃 PaCO2 Arterial CO2 (whats measured on an ABG)
PETCO2 is usually less than PaCO2 because of dead space. If
physiological dead space increases the difference between
PETCO2 and PaCO2 will also rise. Examples include:
揃 Low cardiac output reduced delivery of CO2 to lungs
揃 Blockage of Pulmonary arteries (pulmonary embolus)
PRINCIPLE:
PaCO2
PvCO2
PACO2
PETCO2
45
35
40
40
ETCO2 IN CARDIAC ARREST
ETT CONFIRMATION
Litmus paper changes color based on pH;
exhaled CO2 lowers the pH and causes the the
paper to transiently turn from PURPLE to
YELLOW (MELLOW YELLOW); acidic vomitus can
cause a false permanent color change.
A
B
C
Provides an approximate
PETCO2 reading as each
area is sensitive to
different ETCO2 values:
A <4 MMHG
B 4-15 MMHG
C 15-38 MMHG
39
14
ETCO2
RR
PORTABLE ELECTRONIC CAPNOGRAPH WAVEFORM CAPNOGRAPH
ETCO2
(mmHg)
0
10
20
30
40
50
etCO2
39
RR
14
Side-stream detector
(LONGER LATENCY)
I
II
III
IV
The waveform is composed of 4 phases
揃 Phase I anatomical dead space ventilation
揃 Phase II dead space mixed with alveolar ventilation
揃 Phase III alveolar ventilation (where ETCO2 measured)
揃 Phase IV end of exhalation
CAPNOGRAPH WAVEFORM :
ETCO2 IN PROCEDURAL SEDATION
Measured PETCO2
IR spectroscopy precisely
measures exhaled CO2 content
IR spectroscopy measures exhaled CO2
content and displays results graphically;
can also be used with special nasal
cannula to monitor non-intubated pts.
PROLONGED PHASE II/III 揃 Bronchospasm
揃 Airway obstruction
揃 COPD
CARDIAC OSCILLATIONS 揃 Hypovolemia
揃 Hypoventilation
CURARE CLEFT 揃 Patient dysynchrony
during mechanical
ventilation breath
DIMORPHIC PHASE II/II
揃 Right mainstem intubation
揃 Differential lung emptying
(Single lung transplant, severe
kyphoscoliosis, etc)
PROMINENT PHASE IV 揃 Obesity
揃 Pregnancy
揃 Poor compliance
SUDDEN DROP IN ETCO2 揃 Displaced ETT
揃 Decreased CO (arrythmia, PE, etc)
Adequacy of CPR
揃 Achieving an PETCO2 > 20mmHg is
associated with adequate CPR. If not
achieving this goal consider rotating the
person performing compressions.
Detection of ROSC
揃 Sudden increase in PETCO2 during CPR
is a marker for ROSC.
Determination of futility
揃 Persistent PETCO2 < 10 for > 20 min is
associated with futility, and even 5 min
with ETCO2 < 10 is associated with poor
outcomes.
Confirmation of exhaled CO2 can be used for
ETT placement confirmation. Colorimetric
capnograph is only appropriate in well
perfusing patients; waveform capnograph is
more accurate, particularly in low CO states.
SPECIFIC CAPNOGRAPH PATTERNS:
shark fin
Waveform capnography can be used to
monitor for hypoventilation in non-intubated
patients during procedural sedation (using an
ETCO2 sensor nasal cannula). Waveform
capnography is more sensitive than just SpO2
monitoring, and can detect hypoventilation
up to 60 seconds before desaturation occurs.
揃 Poor gas exchange due to overdistension of alveoli high TV, excessive PEEP, COPD
ETCO2 waveform Peak ETCO2 value
Each heartbeat ejects a
small amount of CO2
Terminal
upswing
DOWNSLOPING PHASE III
揃 Severe emphysema
(alveoli destruction can cause
rapid initial emptying of CO2)
Mainstream
(in-line)
detector
(SHORTER
LATENCY)
CC
BY-SA
3.0
v1.1
(2020-11-18)