This document provides an orientation to infection control and isolation precautions for nurses. It describes the objectives of understanding isolation procedures, antibiotic resistant organisms, and surveillance for hospital acquired infections. It outlines standard, contact, droplet and airborne precautions and gives examples of diseases that require each type of isolation. It provides guidance on proper use of personal protective equipment, including the correct sequence for donning and removing gowns, gloves, masks and respirators. It emphasizes the importance of hand hygiene and cleaning equipment to prevent the spread of infections in the hospital.