8. 頭痛専?医が企画?開発に参加
1 Created with headache expertise
2 Formal psychometric and feasibility testing
3 Clinically relevant headache variables measured
4 Usable
5 Customizable answer options and reports
6 Reports linking multiple variables
7 Export headache data from app
Hundert AS et al JMIR mHealth uHealth 2014
総合内科部?、神経内科部?、頭痛センター?
飯ヶ?医師
9. 臨床試験ガイドラインに準拠
頭痛の臨床試験ガイドラインにおける評価項?を有し
臨床研究への利?が可能
Headache
Percentage of patients pain free at 2h Number of patients pain-free at 2h
with no use of rescue medication or
relapse within 48h
Headache intensity
Headache relief
Time to meaningful relief
Global evaluation of medication
Functional disability
Presence of photo/phonophobia
Patients’ preference for treatment
Consistency of effect
Verbal/numerical rating scale
Percentage of patients with a decrease in
headache from severe or moderate to none
or mild within 2h
Simple verbal scale
Categorical verbal/numerical scale
At least ? of attacks consecutively treated
with active drug
Ustained pain-free Frequency Number of attacks per 4w period
Migraine
frequency Number of attackes per 4w period Headache intensity
Headache duration
Drug consumption for symptomatic
treatment
Patient preference
Same as headache
Number of migraine attacks per 4w period
treated with symptomatic treatment /number
of
Primary outcomes Recommended measures
(with provided)
Secondary outcomes Recommended measures
(when provided)
GUIDELINES FOR CONTROLLED TRIALS OF DRUGS IN MIGRAINE
Cephalalgia 2002
62. 根幹となる資本=健康
WHOの健康の定義
Health is a state of complete physical,
mental and social well-being and not merely
the absence of disease or infirmity.
健康とは、病気でないとか、弱っていないとい
うことではなく、?体的にも、精神的にも、そ
して社会的にも、すべてが満たされた状態にあ
ることをいいます。(?本WHO協会訳)