This document provides an introduction to dosage form design. It discusses the aims of the course, which are to explain pharmaceutical processing, drug formulation, and biopharmaceutics. It also discusses why a dosage form is needed for a drug and lists some key terms related to dosage form design. The document notes that three main factors contribute to designing an effective dosage form: dosage form related factors, drug related factors, and physiological factors. It provides examples of common dosage forms that will be considered, including solid, liquid, gas delivery, semisolid, transdermal, sustained release, and sterile products.
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Lect 1 introduction_to_dosage_form_design_
1. Introduction to Dosage
Form Design
Abubakr O. Nur (M.Pharm; PhD)
Assoc. Prof. in Pharmaceutics (U of K)
August 2010
2. Introduction
What the course aim at?
What are pharmaceutical
processing, drug formulation and
biopharmaceutics?
Why DS or a dosage form for a
drug?
2Dr. Abubakr O. Nur
3. You are already familiar with the
following terms:
Route of administration,
bioavailability, bioequivalence,
biopharmaceutics, rate and extent
of drug absorption, onset of drug
action, first pass effect, dissolution
and disintegration. Are you?????
3Dr. Abubakr O. Nur
4. In fact, to design a dosage form
three factors contribute similarly.
1. Dosage form related factors
2. Drug related factors
3. Physiological factors
4Dr. Abubakr O. Nur
5. Dosage forms to be considered are:
Solid dosage forms (tablets and capsules)
Liquid dosage forms (solution, suspensions and
emulsions)
Gas delivery (aerosols and inhalations)
Semisolid delivery systems (dermatological
products)
Products for Transdermal applications (skin
patches)
Sustained and novel DDS.
Sterile products
5Dr. Abubakr O. Nur