This document discusses valvular heart disease, focusing on the anatomy and physiology of the four heart valves and the spectrum of diseases that can affect each valve. Key valve diseases covered include aortic stenosis, aortic regurgitation, mitral regurgitation, mitral stenosis. For each disease the etiologies, pathophysiology, symptoms, physical exam findings, diagnosis, and treatment options are reviewed. The emphasis is on understanding valve problems in the context of normal cardiac anatomy and function.
10. Spectrum of VHD Right Sided VHD
Tricuspid Valve
Endocarditis
IV drug abusers or in patients with IVs
Carcinoid HD - classically TS
TR common, benign, may be secondary to
Pulm HTN
Pulmonic Valve
Pediatrics Pulm Stenosis
Rheumatic HD PI (Graham Steel Murmur)
Right sided valvular lesions change in intensity with
inspiration
13. Cardiac Physiology 101
Regurg/ Insuff leaking (backflow) of blood across a closed valve
Stenosis Obstruction of (forward) flow across an opened valve
Systole AV/PV opens-------Aortic Stenosis
S1-S2 MV/TV closes------Mitral Regurg
Diastole AV/PV closes------Aortic Regurg
S2-S1 MV/TV opens-------Mitral Stenosis
These concepts are set in stone, it cant occur any other way,
It would be anatomically impossible
23. Aortic Stenosis
Diagnosis
Ecg LAE, LVH
Echo 2D/color doppler test of choice
Cardiac Cath helpful, confirmatory, needed if
the pt is older look at the coronaries
24. Aortic Stenosis
Treatment of Symptomatic Aortic Stenosis or
Decreased LV Function
Medical Therapy treats the symptoms not the cause
Aortic Valve Replacement
Bioprosthetic vs Mechanical AVR
31. Aortic Regurg Austin Flint Murmur
Due to the vibration of the anterior leaflet of the mitral valve
as it is buffetted simultaneously by the blood jets from the left
atrium and the aorta.
32. Aortic Regurgitation
Diagnosis
Ecg LAE, LVH
Echo 2D/color doppler test of choice
Cardiac Cath helpful, confirmatory, needed if
the pt is older look at the coronaries
33. Aortic Regurgitation
Treatment of Asymptomatic Aortic Regurg
Medical Therapy treats the symptoms not the cause
Serial Check ups with Echos (eval EF, Severity AR)
SBE Prophylaxis
Vasodialators (Nifedipine, ACE-I)
Diuretics
Treatment of Symptomatic Aortic Regurg
Aortic Valve Replacement
Bioprosthetic vs Mechanical AVR
34. If you're not confused,
you're not paying
attention.
Tom Peters
36. Mitral Regurgitation
Etiologies
Alterations of the Leaflets, Commissures, Annulus
Rheumatic
MVP
Endocarditis
Alterations of LV or LA size and Function
Papillary Muscle (Ischemic, MI, Myocarditis, DCM)
HOCM
LV Enlargement Cardiomyopathies -
LA Enlargement from MR
MR begets MR
42. Mitral Regurgitation
Diagnosis
Ecg LAE, LVH
Echo 2D/color doppler test of choice
Cardiac Cath helpful, confirmatory, needed if
the pt is older look at the coronaries
45. Mitral Regurgitation -MVP
Diagnosis and Treatment
Echo 2D/Color
B-Blockers (hyperadrenergic symptoms, Palpitations)
Aspirin (TIAs without etiology)
SBE Prophylaxis (only if associated with MR)
Severe Symptomatic MR same as chronic MR
51. Mitral Stenosis
Physical Exam
Loud S1
Opening Snap
Diastolic Apical Rumble (murmur)
May be associated with:
MR or AS
Right Sided Murmurs
o PI Graham Steel Murmur
o TR
52. Mitral Stenosis
Diagnosis
Ecg A Fib, LAE, RAE, RVH
Echo 2D/color doppler test of choice
Cardiac Cath helpful, confirmatory, needed if
the pt is older look at the coronaries
53. Mitral Stenosis
Treatment of Symptomatic Mitral Stenosis
Medical Therapy treats the symptoms not the cause
Diuretics for congestion
Digoxin, Beta and Ca Channel Blockers for Afib
rate control
Anticoagulation for AFib and LA clots
SBE Prophylaxix prevent endocarditis
54. Mitral Stenosis
Treatment of Symptomatic Mitral Stenosis
Surgical Therapy treats the cause
Percutaneous Ballon Valvulaoplasty Non-
calcified, pliable valve