際際滷

際際滷Share a Scribd company logo
Dr. Tahir Abbas (Ph.D. Zoology)
Major Fields of Interest:
Zoology, Toxicology, Teratology, Rehabilitation, Cancer
24 days
64days
Hypothalamus
P.G
T.G FSH, LH
A.G
HRF
Th. G
Androgen
P
O
Sertoli CellLeydigs
Cell
ABP
S.T
ACTIVIN INHIBIN
DHT
TESTOSTERONE
SPERMATOGONIUM
2n
2n
Mitosis
Primary
Spermatocyte
2n
Differentiation
Secondary
Spermatocytes
n
First
Meiotic
Spermatids
Second
Meiotic
n
24days
16 days
ClonalExpansionMaturationDifferentiation
Spermatidogenesis
Spermiogenesis
SPERMATOCYTOGENESIS
SPERMATOGENESIS
Germ line Cell
Spermatozoa
ACTH
Designed by;
Dr. Tahir Abbas
P
53
mRNA
CLEAVAGE EMBRYO
Cleavage Planes
AP
VP
Meridional Sagittal Equatorial Latitudinal
Vertical Transversal
Cleavage Patterns
HOLOBLASTIC MEROBLASTIC
Radial
Superimposed
Deuterostome
Human
Bilateral
Tunicates
Superimposed
Spiral
Not Superimposed
Protostomes
Rotational
Asynchronous
Mammals
Discoidal
Reptiles
Birds
Superficial
Insects
a b c d
*a; alecithal
b; microlecithal
c; macrolecitha
d; telolecithal
e; mesolecithal
f; centrolecithal
TYPES OF EGGS

...
..
e f
a, b b e, f b, e c e, f
Design by;
Dr. Tahir Abbas
P
MAT
MITOTIC PHASE
G1
S
Go
9 h
10 h
3.5-5 h
0.5 h
Pre-mitosis Check PointPost-mitosis Check Point
Cyclin B, CDK 1
Cyclin A, CDK 2
Cyclin A, CDK 1
CDK 2, Cyclin E
53
PAdenyl cyclase
cAMP
m RNA
PTK
Glucose
INSULUN
organizer
硫-catenin
Homeobox genes
MPFPrepared by Dr. Tahir Abbas
PL-C
PIP2
DAG E.R
INTERPHASE
KARYO
KINESIS
MITOSIS
P; prophase, G; gap, M;
metaphase, A; anaphase, T;
telophase, S; synthesis, P53;
protein forming gene, MPF;
maturation promoting factor,
PTK; protein tyrosine kinase,
PL-C; phospholipase, PIP2;
phosphatidyl inositol
bisphosphate, DAG; diaceyl
glycerol, E.R; endoplasmic
reticulum
Check Point
REGULATION
OF
CELL CYCLE
&
CLEAVAGE
Ovary
Egg
F
Oviduct
Ampulla
24 hc
Morula
16 cell
cavitation
Trophoblast
b. c
Blastocyst
ICM (13 C)
64 Cell
50 Cell
DIFFERENTIATION
FGF
ZP
hatching
Endometrium
implantation Decidua
EPIBLAST HYPOBLAST
Extra-embryonic
Endoderm
Yolk Sac
Embryonic Epiblast Amniotic Epiblast
ECTODERM Primitive Streak
ENDODERM Mesoderm
Embryonic Mesoderm
Extra - embryonic
Mesoderm
Amnion
Integumentary
Nervous
MESODERM
Skin, hair, glands as sweat,
sebaceous, mammary & nail
Anterior Lobe of Pituitary
Gland, Eye Lens cell
Epithelium of oral cavity
& nose, teeth covering
BRAIN, SPINAL CORD
Posterior Lobe of Pituitary Gland
Medulla of Adrenal Gland
Sensory,
Motor Nerves
Intermediate
mesodermReproductive System
Renal System
Lung, Thyroid,
Thymus, Trachea
Middle Ear , Liver
Ovary
Uterus
Oviduct
Vagina
Testes, Vas
deference
Epididymis
Dorsal
mesoderm
Kidney
Nephron
Muscles
Axial Skeleton
Lateral
mesoderm
Pleura
Respiratory
Parts
Cortex of Adrenal Gland
Heart
Blood Cells
Blood Vessels
Pericardium
Allantois
Placenta attach
Umbilical cord
Prepared by;
Dr. Tahir Abbas
tahirabbasbloch@gmail.com
5D
7D
Haemochorial
Placenta
18-20D
Chorion
*
*
Extra-Embryonic
Layers
30-50D
0D
Pharynx, Pancreas,
GIT, Parathyroid
Epiboly
Invagination
Convergent Extension
Ectoderm
Spemanns Organizer
Intercalation
SHH
PKT PL-C PIP E.R Ca
++
Cadherin
硫-catenin
mRNA
Animal
Hemisphere
Blastula Gastrulation
Mesoderm
Endoderm
C A M
Bottle Cells
NOG NOGGIN
17
Notochord
FGF TGF-硫
Wnt
SMAD
Growth
BMP
CHORDIN
ACTIVIN Follistatin
7
Muscle GIT
Ectoderm
E
X
T
E
R
N
A
L
E
C
T
O
D
E
R
M
External Skin
Hair
Nails
Epithelium
Lens
Eye Glands
Tooth
Enamel
Anterior P.G
Cornea
Receptors
Nasal Cavity
Dental
Optic Nerves
Mesenchyme
Retina
N
E
U
R
O
E
C
T
O
D
E
R
M
Neural Tube
BRAIN
Spinal
Cord
Neural Crest
Skin PigmentsANS
V.H
Adrenal
Medulla
Septa
Prepared by;
Dr. Tahir Abbas
tahirabbasbloch@gmail.com
DAG
Spemanns Organizer
PKT PL-C PIP E.R
Ca
++
硫-catenin
mRNA
Blastula
Gastrulation
TF NOGIN
17
FGF
TGF-硫
Wnt
BMP
CHORDIN
7
Prepared by;
Dr. Tahir Abbas
tahirabbasbloch@gmail.com
A
10
DAG
A.Cap
Dorsal
Ventral
V.Cap
Dorsal V.P
Ventral V.P
Dorsal A.P
Ventral A.P
G.C
cAMP
Ca
30
Follistatin
Dorsal
Lip
Ventral
Lip
Gremlin
Dorsal Vegetal Cell
Nieuwkoop Center
Bicoid CADHERIN
SIAMOIS
AD
DBD
SSD
Ligand
MyC
SMAD
CAM
DORSAL
VENTRAL
A P
Blemmyes
Megacephaly
Conjoin Twin
PAX
NODAL
Glucose
G-6-P
F-1, 6-BP
3-PG
P.A
Operon
Lac-
SHH
HOX
Activin
ECTODERM
MESODERM
ENDODERM
MESODERM
ENDODERM
Neuroectoderm
N-Cadherin
Neural Crest
Somite
Neural Fold
Notochord
Neural Groove
Neural Ridges
Neural Fold
Primary Neurulation
Secondary Neurulation
Designed by;
Dr. Tahir Abbas
PROSENCEPHALON
MESENCEPHALON
RHOMBENCEPHALON
Telencephalon
Diencephalon
Metencephalon
Myelencephalon
Cerebral Hemisphere
Hypothalamus
Thalamus
Mid Brain
Pons
Cerebellum
Medulla
Spinal Cord
Neural Tube
NeuralEpithelialCell
Spina Bifida
Neural Progenitor Cells

More Related Content

Lectures,Teaching plan, Development

  • 1. Dr. Tahir Abbas (Ph.D. Zoology) Major Fields of Interest: Zoology, Toxicology, Teratology, Rehabilitation, Cancer
  • 2. 24 days 64days Hypothalamus P.G T.G FSH, LH A.G HRF Th. G Androgen P O Sertoli CellLeydigs Cell ABP S.T ACTIVIN INHIBIN DHT TESTOSTERONE SPERMATOGONIUM 2n 2n Mitosis Primary Spermatocyte 2n Differentiation Secondary Spermatocytes n First Meiotic Spermatids Second Meiotic n 24days 16 days ClonalExpansionMaturationDifferentiation Spermatidogenesis Spermiogenesis SPERMATOCYTOGENESIS SPERMATOGENESIS Germ line Cell Spermatozoa ACTH Designed by; Dr. Tahir Abbas P 53 mRNA
  • 3. CLEAVAGE EMBRYO Cleavage Planes AP VP Meridional Sagittal Equatorial Latitudinal Vertical Transversal Cleavage Patterns HOLOBLASTIC MEROBLASTIC Radial Superimposed Deuterostome Human Bilateral Tunicates Superimposed Spiral Not Superimposed Protostomes Rotational Asynchronous Mammals Discoidal Reptiles Birds Superficial Insects a b c d *a; alecithal b; microlecithal c; macrolecitha d; telolecithal e; mesolecithal f; centrolecithal TYPES OF EGGS ... .. e f a, b b e, f b, e c e, f Design by; Dr. Tahir Abbas
  • 4. P MAT MITOTIC PHASE G1 S Go 9 h 10 h 3.5-5 h 0.5 h Pre-mitosis Check PointPost-mitosis Check Point Cyclin B, CDK 1 Cyclin A, CDK 2 Cyclin A, CDK 1 CDK 2, Cyclin E 53 PAdenyl cyclase cAMP m RNA PTK Glucose INSULUN organizer 硫-catenin Homeobox genes MPFPrepared by Dr. Tahir Abbas PL-C PIP2 DAG E.R INTERPHASE KARYO KINESIS MITOSIS P; prophase, G; gap, M; metaphase, A; anaphase, T; telophase, S; synthesis, P53; protein forming gene, MPF; maturation promoting factor, PTK; protein tyrosine kinase, PL-C; phospholipase, PIP2; phosphatidyl inositol bisphosphate, DAG; diaceyl glycerol, E.R; endoplasmic reticulum Check Point REGULATION OF CELL CYCLE & CLEAVAGE
  • 5. Ovary Egg F Oviduct Ampulla 24 hc Morula 16 cell cavitation Trophoblast b. c Blastocyst ICM (13 C) 64 Cell 50 Cell DIFFERENTIATION FGF ZP hatching Endometrium implantation Decidua EPIBLAST HYPOBLAST Extra-embryonic Endoderm Yolk Sac Embryonic Epiblast Amniotic Epiblast ECTODERM Primitive Streak ENDODERM Mesoderm Embryonic Mesoderm Extra - embryonic Mesoderm Amnion Integumentary Nervous MESODERM Skin, hair, glands as sweat, sebaceous, mammary & nail Anterior Lobe of Pituitary Gland, Eye Lens cell Epithelium of oral cavity & nose, teeth covering BRAIN, SPINAL CORD Posterior Lobe of Pituitary Gland Medulla of Adrenal Gland Sensory, Motor Nerves Intermediate mesodermReproductive System Renal System Lung, Thyroid, Thymus, Trachea Middle Ear , Liver Ovary Uterus Oviduct Vagina Testes, Vas deference Epididymis Dorsal mesoderm Kidney Nephron Muscles Axial Skeleton Lateral mesoderm Pleura Respiratory Parts Cortex of Adrenal Gland Heart Blood Cells Blood Vessels Pericardium Allantois Placenta attach Umbilical cord Prepared by; Dr. Tahir Abbas tahirabbasbloch@gmail.com 5D 7D Haemochorial Placenta 18-20D Chorion * * Extra-Embryonic Layers 30-50D 0D Pharynx, Pancreas, GIT, Parathyroid
  • 6. Epiboly Invagination Convergent Extension Ectoderm Spemanns Organizer Intercalation SHH PKT PL-C PIP E.R Ca ++ Cadherin 硫-catenin mRNA Animal Hemisphere Blastula Gastrulation Mesoderm Endoderm C A M Bottle Cells NOG NOGGIN 17 Notochord FGF TGF-硫 Wnt SMAD Growth BMP CHORDIN ACTIVIN Follistatin 7 Muscle GIT Ectoderm E X T E R N A L E C T O D E R M External Skin Hair Nails Epithelium Lens Eye Glands Tooth Enamel Anterior P.G Cornea Receptors Nasal Cavity Dental Optic Nerves Mesenchyme Retina N E U R O E C T O D E R M Neural Tube BRAIN Spinal Cord Neural Crest Skin PigmentsANS V.H Adrenal Medulla Septa Prepared by; Dr. Tahir Abbas tahirabbasbloch@gmail.com DAG
  • 7. Spemanns Organizer PKT PL-C PIP E.R Ca ++ 硫-catenin mRNA Blastula Gastrulation TF NOGIN 17 FGF TGF-硫 Wnt BMP CHORDIN 7 Prepared by; Dr. Tahir Abbas tahirabbasbloch@gmail.com A 10 DAG A.Cap Dorsal Ventral V.Cap Dorsal V.P Ventral V.P Dorsal A.P Ventral A.P G.C cAMP Ca 30 Follistatin Dorsal Lip Ventral Lip Gremlin Dorsal Vegetal Cell Nieuwkoop Center Bicoid CADHERIN SIAMOIS AD DBD SSD Ligand MyC SMAD CAM DORSAL VENTRAL A P Blemmyes Megacephaly Conjoin Twin PAX NODAL Glucose G-6-P F-1, 6-BP 3-PG P.A Operon Lac- SHH HOX Activin
  • 8. ECTODERM MESODERM ENDODERM MESODERM ENDODERM Neuroectoderm N-Cadherin Neural Crest Somite Neural Fold Notochord Neural Groove Neural Ridges Neural Fold Primary Neurulation Secondary Neurulation Designed by; Dr. Tahir Abbas PROSENCEPHALON MESENCEPHALON RHOMBENCEPHALON Telencephalon Diencephalon Metencephalon Myelencephalon Cerebral Hemisphere Hypothalamus Thalamus Mid Brain Pons Cerebellum Medulla Spinal Cord Neural Tube NeuralEpithelialCell Spina Bifida Neural Progenitor Cells