1. The document discusses Dr. Tahir Abbas and his fields of interest which include zoology, toxicology, teratology, rehabilitation, and cancer.
2. It then covers topics related to cell cycle regulation, gametogenesis, cleavage, types of eggs, and embryogenesis including germ layer formation and fetal development.
3. Diagrams and descriptions of topics like gastrulation, neurulation, and brain development are also included.
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Lectures,Teaching plan, Development
1. Dr. Tahir Abbas (Ph.D. Zoology)
Major Fields of Interest:
Zoology, Toxicology, Teratology, Rehabilitation, Cancer
2. 24 days
64days
Hypothalamus
P.G
T.G FSH, LH
A.G
HRF
Th. G
Androgen
P
O
Sertoli CellLeydigs
Cell
ABP
S.T
ACTIVIN INHIBIN
DHT
TESTOSTERONE
SPERMATOGONIUM
2n
2n
Mitosis
Primary
Spermatocyte
2n
Differentiation
Secondary
Spermatocytes
n
First
Meiotic
Spermatids
Second
Meiotic
n
24days
16 days
ClonalExpansionMaturationDifferentiation
Spermatidogenesis
Spermiogenesis
SPERMATOCYTOGENESIS
SPERMATOGENESIS
Germ line Cell
Spermatozoa
ACTH
Designed by;
Dr. Tahir Abbas
P
53
mRNA
3. CLEAVAGE EMBRYO
Cleavage Planes
AP
VP
Meridional Sagittal Equatorial Latitudinal
Vertical Transversal
Cleavage Patterns
HOLOBLASTIC MEROBLASTIC
Radial
Superimposed
Deuterostome
Human
Bilateral
Tunicates
Superimposed
Spiral
Not Superimposed
Protostomes
Rotational
Asynchronous
Mammals
Discoidal
Reptiles
Birds
Superficial
Insects
a b c d
*a; alecithal
b; microlecithal
c; macrolecitha
d; telolecithal
e; mesolecithal
f; centrolecithal
TYPES OF EGGS
...
..
e f
a, b b e, f b, e c e, f
Design by;
Dr. Tahir Abbas
4. P
MAT
MITOTIC PHASE
G1
S
Go
9 h
10 h
3.5-5 h
0.5 h
Pre-mitosis Check PointPost-mitosis Check Point
Cyclin B, CDK 1
Cyclin A, CDK 2
Cyclin A, CDK 1
CDK 2, Cyclin E
53
PAdenyl cyclase
cAMP
m RNA
PTK
Glucose
INSULUN
organizer
硫-catenin
Homeobox genes
MPFPrepared by Dr. Tahir Abbas
PL-C
PIP2
DAG E.R
INTERPHASE
KARYO
KINESIS
MITOSIS
P; prophase, G; gap, M;
metaphase, A; anaphase, T;
telophase, S; synthesis, P53;
protein forming gene, MPF;
maturation promoting factor,
PTK; protein tyrosine kinase,
PL-C; phospholipase, PIP2;
phosphatidyl inositol
bisphosphate, DAG; diaceyl
glycerol, E.R; endoplasmic
reticulum
Check Point
REGULATION
OF
CELL CYCLE
&
CLEAVAGE
5. Ovary
Egg
F
Oviduct
Ampulla
24 hc
Morula
16 cell
cavitation
Trophoblast
b. c
Blastocyst
ICM (13 C)
64 Cell
50 Cell
DIFFERENTIATION
FGF
ZP
hatching
Endometrium
implantation Decidua
EPIBLAST HYPOBLAST
Extra-embryonic
Endoderm
Yolk Sac
Embryonic Epiblast Amniotic Epiblast
ECTODERM Primitive Streak
ENDODERM Mesoderm
Embryonic Mesoderm
Extra - embryonic
Mesoderm
Amnion
Integumentary
Nervous
MESODERM
Skin, hair, glands as sweat,
sebaceous, mammary & nail
Anterior Lobe of Pituitary
Gland, Eye Lens cell
Epithelium of oral cavity
& nose, teeth covering
BRAIN, SPINAL CORD
Posterior Lobe of Pituitary Gland
Medulla of Adrenal Gland
Sensory,
Motor Nerves
Intermediate
mesodermReproductive System
Renal System
Lung, Thyroid,
Thymus, Trachea
Middle Ear , Liver
Ovary
Uterus
Oviduct
Vagina
Testes, Vas
deference
Epididymis
Dorsal
mesoderm
Kidney
Nephron
Muscles
Axial Skeleton
Lateral
mesoderm
Pleura
Respiratory
Parts
Cortex of Adrenal Gland
Heart
Blood Cells
Blood Vessels
Pericardium
Allantois
Placenta attach
Umbilical cord
Prepared by;
Dr. Tahir Abbas
tahirabbasbloch@gmail.com
5D
7D
Haemochorial
Placenta
18-20D
Chorion
*
*
Extra-Embryonic
Layers
30-50D
0D
Pharynx, Pancreas,
GIT, Parathyroid
6. Epiboly
Invagination
Convergent Extension
Ectoderm
Spemanns Organizer
Intercalation
SHH
PKT PL-C PIP E.R Ca
++
Cadherin
硫-catenin
mRNA
Animal
Hemisphere
Blastula Gastrulation
Mesoderm
Endoderm
C A M
Bottle Cells
NOG NOGGIN
17
Notochord
FGF TGF-硫
Wnt
SMAD
Growth
BMP
CHORDIN
ACTIVIN Follistatin
7
Muscle GIT
Ectoderm
E
X
T
E
R
N
A
L
E
C
T
O
D
E
R
M
External Skin
Hair
Nails
Epithelium
Lens
Eye Glands
Tooth
Enamel
Anterior P.G
Cornea
Receptors
Nasal Cavity
Dental
Optic Nerves
Mesenchyme
Retina
N
E
U
R
O
E
C
T
O
D
E
R
M
Neural Tube
BRAIN
Spinal
Cord
Neural Crest
Skin PigmentsANS
V.H
Adrenal
Medulla
Septa
Prepared by;
Dr. Tahir Abbas
tahirabbasbloch@gmail.com
DAG
7. Spemanns Organizer
PKT PL-C PIP E.R
Ca
++
硫-catenin
mRNA
Blastula
Gastrulation
TF NOGIN
17
FGF
TGF-硫
Wnt
BMP
CHORDIN
7
Prepared by;
Dr. Tahir Abbas
tahirabbasbloch@gmail.com
A
10
DAG
A.Cap
Dorsal
Ventral
V.Cap
Dorsal V.P
Ventral V.P
Dorsal A.P
Ventral A.P
G.C
cAMP
Ca
30
Follistatin
Dorsal
Lip
Ventral
Lip
Gremlin
Dorsal Vegetal Cell
Nieuwkoop Center
Bicoid CADHERIN
SIAMOIS
AD
DBD
SSD
Ligand
MyC
SMAD
CAM
DORSAL
VENTRAL
A P
Blemmyes
Megacephaly
Conjoin Twin
PAX
NODAL
Glucose
G-6-P
F-1, 6-BP
3-PG
P.A
Operon
Lac-
SHH
HOX
Activin