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LOHASAIN
Tablets
60%-70% bond to Hemoglobin
3% bond to Mioglobin
15% bond to enzymes (nervous system cells)
IRON METABOLISM
20%-30% bond to Ferritin
Ferro di Trasporto 0,1% bond to Transferrin
Transport Iron
Ferro di Riserva
Reserve Iron
Ferro Attivo
Active Iron
LOHASAIN
Iron absorption and metabolism is
strongly regulated
Usually only 10-15% of iron intake
is absorbed
This is true for foods, supplements or
drugs
LOHASAIN
LIPOSOME
Iron
Pyrophosphate
LOHASAIN
ABSORPTION
 Liposomal iron absorption is significatly different from free iron intestinal
absorption.
 Liposomes are DIRECTLY absorbed and only in the liver epatocytes break
down liposome membrane.
LIPOSOMIAL IRON
LOHASAIN
LOHASAIN
Direct Absorption
M CELLS
M Cells
(endocitosis)
Macrophages
(Peyer's patch)
Lymphatic transport
LOHASAIN
Thanks to liposomal technology, the iron will never react
with intestinal and other mucosaes
LIPOSOMIAL IRON
NO SIDE EFFECTS
LOHASAIN
Absorption and Bioavailability
Thanks to the liposome technology, bioavailability of iron increases by 3.5 times compared with the
same iron source with non-liposome form (rats study)
LOHASAIN
The percentage of bioavailable iron from Sideral is significantly higher - 4.1 times -
than Ferrous Gluconate (rats study)
Absorption and Bioavailability
LOHASAIN
Also compared with Ferrous Sulfate,
Ferrous Pyrophosphate ensures superior bioavailability: 2.7 times
Absorption and Bioavailability
LOHASAIN
Also compared with Ferrous Fumarate,
Sideral ensures 5 times higher iron plasma concentration (rats study)
Absorption and Bioavailability
LOHASAIN
LOHASAIN
LOHASAIN
UNIQUE SELLING POINTS
 High bioavailability
 No metallic taste
 No fat / vitamin oxidation
 No digestive tract irritation (even at high dose)
 Available for celiacs (gluten free)
 Only 30 mg liposomal iron, hence lesser metabolic load
 Vitamin C: Scavenges free radicles
 Glycine supports Hb rise
 Vitamin B12 help in faster Hb rise
 L-Methyl Folate: An active form of Folic acid prevents neural
tube defects during pregnancy
LOHASAIN
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Lohasain Medical.pptx

  • 2. 60%-70% bond to Hemoglobin 3% bond to Mioglobin 15% bond to enzymes (nervous system cells) IRON METABOLISM 20%-30% bond to Ferritin Ferro di Trasporto 0,1% bond to Transferrin Transport Iron Ferro di Riserva Reserve Iron Ferro Attivo Active Iron LOHASAIN
  • 3. Iron absorption and metabolism is strongly regulated Usually only 10-15% of iron intake is absorbed This is true for foods, supplements or drugs LOHASAIN
  • 5. ABSORPTION Liposomal iron absorption is significatly different from free iron intestinal absorption. Liposomes are DIRECTLY absorbed and only in the liver epatocytes break down liposome membrane. LIPOSOMIAL IRON LOHASAIN
  • 7. Direct Absorption M CELLS M Cells (endocitosis) Macrophages (Peyer's patch) Lymphatic transport LOHASAIN
  • 8. Thanks to liposomal technology, the iron will never react with intestinal and other mucosaes LIPOSOMIAL IRON NO SIDE EFFECTS LOHASAIN
  • 9. Absorption and Bioavailability Thanks to the liposome technology, bioavailability of iron increases by 3.5 times compared with the same iron source with non-liposome form (rats study) LOHASAIN
  • 10. The percentage of bioavailable iron from Sideral is significantly higher - 4.1 times - than Ferrous Gluconate (rats study) Absorption and Bioavailability LOHASAIN
  • 11. Also compared with Ferrous Sulfate, Ferrous Pyrophosphate ensures superior bioavailability: 2.7 times Absorption and Bioavailability LOHASAIN
  • 12. Also compared with Ferrous Fumarate, Sideral ensures 5 times higher iron plasma concentration (rats study) Absorption and Bioavailability LOHASAIN
  • 15. UNIQUE SELLING POINTS High bioavailability No metallic taste No fat / vitamin oxidation No digestive tract irritation (even at high dose) Available for celiacs (gluten free) Only 30 mg liposomal iron, hence lesser metabolic load Vitamin C: Scavenges free radicles Glycine supports Hb rise Vitamin B12 help in faster Hb rise L-Methyl Folate: An active form of Folic acid prevents neural tube defects during pregnancy LOHASAIN