Lupus Bowl 2015

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El lupus fue descrito por primera vez en el siglo XIII. Es una enfermedad autoinmune crónica que daña los órganos, tejidos y células mediante la adherencia de autoanticuerpos. Afecta principalmente a mujeres en edad fértil y se manifiesta a través de síntomas cutáneos, musculoesqueléticos, hematológicos, cardiopulmonares, renales y neurológicos. Su tratamiento depende de la gravedad de los síntomas y puede incluir medidas generales, fárm

Systemic lupus erythematosusBuddhika Illeperuma

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Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by inflammation in tissues throughout the body. The name comes from a 13th century physician who observed facial lesions resembling a wolf bite. Diagnosis is based on criteria developed by the American College of Rheumatology including malar rash, discoid lesions, arthritis, serositis, renal disease, and immunologic abnormalities. Treatment involves hydroxychloroquine, corticosteroids, immunosuppressants like azathioprine. Lupus nephritis requires aggressive therapy with glucocorticoids, cyclophosphamide or mycophenolate mofetil. Treatment goals are complete or partial renal response through reduction

Systemic lupus erythematosusPratap Tiwari

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Lupus eritematoso sistémicoMariana Alvarado Navarrete

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Este documento resume las características del lupus eritematoso sistémico (LES), incluyendo su definición como una enfermedad autoinmune crónica con componente inflamatorio importante, su epidemiología con mayor prevalencia en mujeres entre 20-40 años, sus múltiples manifestaciones clínicas que afectan la piel, articulaciones, riñones y otros órganos, y su tratamiento con medidas generales, medicamentos antiinflamatorios e inmunosupresores.

Systemic lupus erythematosusfaculty of nursing Tanta University

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Systemic Lupus Erythematosus (SLE) is an autoimmune disease where the immune system attacks its own tissues. It most commonly affects women aged 15-40. The exact causes are unknown but genetics, viruses, sunlight, and some drugs may play a role. Symptoms vary but can include rashes, joint pain, fatigue, and organ inflammation. Diagnosis involves blood tests and potentially biopsies. Treatment focuses on rest, sun protection, medications like NSAIDs, antimalarials, corticosteroids, and immunosuppressants to control disease activity and prevent organ damage. Nursing care aims to manage symptoms, prevent infections, and educate patients.

Systemic Lupus ErythematosusLohit Chauhan

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Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect various organs in the body. It is more common in women, especially of childbearing age, and in African Americans. The disease is characterized by autoantibody production and tissue damage caused by immune complexes. Diagnosis is based on meeting criteria from the SLICC classification system, which improved upon previous criteria. Organ manifestations include renal, neurological, cardiac, pulmonary, hematological and cutaneous involvement. Management aims to suppress symptoms and prevent organ damage through medications like glucocorticoids, antimalarials, immunosuppressants and biologics. The goal is complete remission though sustained remission is rare

SYSTEMIC LUPUS ERYTHEMATOSUS Sle pathophysiology and managementsamirelansary

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This document provides an overview and update on systemic lupus erythematosus (SLE). It discusses the definition and classification criteria for SLE, including revisions to the criteria. Genetic factors contributing to SLE susceptibility are described. Increased levels of interferon alpha are implicated in the disease pathogenesis. Clinical manifestations and leading causes of mortality in SLE patients are summarized. Current therapeutic approaches for SLE, including hydroxychloroquine, belimumab, and targeted therapies in development are outlined.

Lupus eritematoso sistemicoFabio De La Hoz

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El lupus eritematoso sistémico es una enfermedad autoinmunitaria que afecta principalmente a mujeres y se caracteriza por la producción de autoanticuerpos que dañan los órganos y tejidos. Se cree que factores genéticos y ambientales como infecciones virales o exposición a la luz UV activan respuestas inmunitarias anormales que conducen a la formación de anticuerpos contra antígenos nucleares. El diagnóstico se basa en criterios clínicos y de laboratorio. El tratamiento incluye

Systemic Lupus ErythematosusDiscover Clinical Trials

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Systemic Lupus ErythematosusSheelendra Shakya

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This document discusses systemic lupus erythematosus (SLE), a complex autoimmune disorder with multifactorial origins. It causes activation of T and B cells leading to autoantibody production. The pathogenesis involves genetic, hormonal and environmental factors interacting to cause immune dysregulation and failure of self-tolerance. SLE can affect many organ systems and presents with a variety of clinical manifestations involving the skin, kidneys, joints, blood, and more. Diagnosis is based on identifying 4 out of 11 diagnostic criteria. Investigations help assess disease activity and organ involvement. Treatment involves immunosuppression with corticosteroids and other drugs depending on disease severity and organ involvement.

Lupus Eritematoso SistemicoDania Mieses

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El lupus eritematoso sistémico (LES) es el prototipo de enfermedad autoinmune multisistémica inflamatoria causada por la producción exagerada de autoanticuerpos. Afecta principalmente a mujeres en edad fértil y se manifiesta a través de síntomas musculoesqueléticos, hematológicos, neurológicos, cardiopulmonares y renales. El diagnóstico se basa en el cuadro clínico y la presencia de autoanticuerpos como los antinucleares. El tratamiento incl

SLEOmar Moatamed

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Systemic lupus erythematosus (SLE) is an autoimmune disease where the immune system attacks its own tissues, causing inflammation and damage. It is characterized by periods of disease flares and remission. Common symptoms include joint pain, rashes, and fatigue. SLE can affect many organs like the skin, lungs, heart, and kidneys. Diagnosis involves evaluating symptoms, lab tests like antinuclear antibodies, and sometimes biopsies. Treatment aims to reduce symptoms during flares and prevent organ damage using medications like corticosteroids, antimalarials, and immunosuppressants. SLE affects mostly women of childbearing age and has no known cure.

Systemic lupus erythematosusFurqan Khan

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Lupus eritematoso sistemicoAbel Quintana

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El documento presenta un resumen sobre el lupus eritematoso sistémico (LES). El LES es un proceso inflamatorio crónico que afecta múltiples órganos y sistemas debido a la producción de autoanticuerpos, depósito de complejos inmunes y activación del sistema del complemento. Los síntomas más comunes son manifestaciones cutáneas, articulares y hematológicas. El tratamiento incluye medicamentos antiinflamatorios, corticoides, antimaláricos y agentes citotóxicos.

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Lupus Bowl 2015

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Lupus Bowl 2015