Reuse of clinical information for research. Paper for the Medical Informatics Europe 2015 conference (Madrid).
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Reuse of EHRs to support Clinical Research
1. Most hospitals have already implemented information
systems and Electronic Health Records (EHRs), but the
reuse of such data for research is still infrequent.
We present a pilot project on the exploitation of clinical
information from a Spanish hospital database system in
the context of the European project “European Medical
Information Framework”.
(EMIF website: http://www.emif.eu)
Introduction Methods
Results
Conclusions
Reuse of EHRs to Support Clinical Research in
a Hospital of Reference
Miguel A. MAYERa,, Laura I. FURLONGa, Pilar TORREb, Ignasi PLANASb, Francesc COTSb, Elisabet IZQUIERDOb, Jordi PORTABELLAb,
Javier ROVIRAb, Alba GUTIERREZ-SACRISTANa and Ferran SANZa
a Research Programme on Biomedical Informatics, IMIM - Universitat Pompeu Fabra, bParc de Salut MAR (PSMAR), Barcelona, Spain
contact: mmayer@imim.es; @mmayerp
- After an anonymization process, all the patients with at least
one recorded diagnosis in the “Parc de Salut MAR (PSMAR)”
EHRs system database, were included for analysis
- Based on the International Classification of Diseases-Clinical
Modification (ICD9-CM) codes and a particular period of time
as selection criteria (between January 1990 and March
2015), several subsets of patients were chosen for analysis
This work has received support from the EU/EFPIA Innovative Medicines Initiative Joint Undertaking (EMIF grant n° 115372) and the ISCIII-FEDER (CP10/00524, PI13/00082).
The Research Programme on Biomedical Informatics (GRIB) is a node of the Spanish National Institute of Bioinformatics (INB).
- 1,333,748 patients were registered in the EHR system
of the “Parc de Salut Mar” in the period of time
considered, from different hospitals and care facilities
(admissions, major ambulatory surgical unit, outpatients
and emergency room)
- Follow-up of patients: mean 6.37 years (SD 6.824)
- 710,366 had at least one diagnosis code in ICD9-CM
- Subset of Dementia: 9,351 patients with dementia
(based on the following ICD9 codes: 290.0, 290.1,
290.10, 290.11, 290.12, 290.13, 290.2, 290.20, 290.21,
290.3, 290.4, 290.40, 290.41, 290.42, 290.43, 290.9,
291.2, 292.82, 294.1, 294.10, 294.20, 294.21, 331.0,
331.1, 331.11, 331.19, 331.82)
- Subset of Diabetes Mellitus type 2: 31,481 patients with
diabetes mellitus type 2
- The huge amount of information available in EHRs requires the use of powerful tools to manage it for biomedical research
- The possibility to analyse the features of specific groups of patients based on their different diagnosis and clinical data by
integrating the information from several separated clinical databases, can provide new insights about relationships
between biomedical entities and prescriptions
- The discovery of new relationships among different conditions will contribute to improve decision-making, quality
management, healthcare and research
Medical Informatics Europe, Madrid, May 2015