This document outlines different types of metabolic disorders including metabolic acidosis, respiratory acidosis, and metabolic alkalosis. It lists potential causes such as ethylene glycol or methanol poisoning for elevated anion and osmolal gaps. For respiratory alkalosis, it suggests causes like hyperventilation, pulmonary disease, or vasculature disease. Metabolic alkalosis is divided into chloride responsive or resistant forms linked to gastrointestinal or renal loss of chloride versus conditions like hyperaldosteronism.
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Metabolic disorders supplement
1. October 6, 2012 METABOLIC DISORDERS
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HCO3
Decreased
pH
Low
Metabolic
Acidosis
Anion Gap
Elevated
Osmolal gap
Elevated
Consider
Ethylene
Glycol or
Methanol
Normal
Consider Ketoacidosis,
Lactic Acidosis, Renal
Failure, ASA Toxicity
Normal
Urine Anion
Gap
Negative
Extra Renal
Cause
Respiratory
Alkalosis
Postive
High
Renal Cause
Pulmonary
Vasculature
Disease
Pulmonary
Parenchymal
Disease
Hyperventilati
on
Elevated
pH
Low
Respiratory
Acidosis
Hypoventilatio
n
CNS
Depression
Respiratory
Muscle
Weakness
Airway
Obstruction V/Q Mismatch
High
Metabolic
AlkalosisUrine
Chloride
<20 mEq/L
Chloride
Responsive
Gastrointestina
l Loss Renal Loss
Alkali
Administration
Contraction
Alkalosis
>20 mEq/L
Chloride
Resistant
Hyperaldoster
onism
Zebras
Call
Nephrology