This document discusses Microbial Robotics' open synthetic biology model and business plan. The company aims to rapidly prototype synthetic biology-based bacteria and viruses for industry experts through an open model. By shipping consumables, platforms, and knowledge across borders instead of genetically modified organisms, the company solves issues around international shipping restrictions. The company also focuses on achieving rapid return on investment through its Open Therapeutics subsidiary and exit strategy within 5 years of starting projects. Projections estimate strong revenue, margin, and EBITDA growth through 2019 as subsidiaries are acquired by larger companies.
2. WITH SMALL
ORGANISMS
With an Open model, rapidly prototyping synthetic biology-based bacteria
and viruses for chemical, therapeutic, and water industry experts.
SOLVING BIG PROBLEMS
JASON E. BARKELOO, CEO
3. WHY OPEN SYNTHETIC BIOLOGY MODEL?
[11] United States Patent and Trademark Of?ce, Patent Pools:A Solution to the Problem of Access in Biotechnology Patents? (Dec 5, 2000)
available at http://www.uspto.gov/web/of?ces/pac/dapp/opla/patentpool.pdf .The USPTO noted two of the most pro?table in the biotechnology
area are those of Cohen and Boyer, which are owned by Stanford University. Stanford minimized licensing fees and extended non-exclusive
licenses.This discouraged would-be infringers since the cost of obtaining a license is low. Instead of encourage infringement and patent trolling,
the ease of non-exclusive licenses meant broad distribution and spurred further innovation. See also National Research Council, Intellectual
Property Rights and Research Tools in Molecular Biology (1996), available at http://www.nap.edu/readingroom/books/property/5.html. ?
¡°With respect to biologics commercialization, the U.S. Patent andTrademark Of?ce
(USPTO) speci?cally noted the open (patent-pool) approach:
¡®No single company or organization, however, has the resources to develop any
signi?cant fraction of the genetic information present in an organism. If proprietary
information is not freely available or licensed in an affordable manner, researchers
will be precluded from using these protected nucleic acids to develop new
therapeutics and diagnostics. It would be, however, shortsighted of a patent holder
to demand such a prohibitively expensive licensing agreement that would preclude
anyone else from utilizing a patented invention. . . . By minimizing licensing fees and
extending non-exclusive licenses, potential infringers were inclined to obtain
licenses and the technology was therefore broadly distributed. . . .¡¯[11]¡±
5. YEARS
Pablo Pomposiello?
PhD
Bacterial Physiology
Consultant
Timothy P. Cripe
MD, PhD
Oncolytics Consultant
Ravi N. Samy
MD, FACS
Chief Medical Of?cer
Jason E. Barkeloo
MA
Founder & CEO
Shengchang Su
PhD
Director
MicrobialBots and
GeRM Engineering?
Li Guo
PhD
Director
Cellular
Engineering
Jay Springer
JD
Director
Regulatory ?
and Legal Affairs
Jin Kong
JD
Director
GlobalSynBio &
Open Therapeutics
EXPERIENCE
100+
K. Krishnamoorthy
MD
Chief Medical Of?cer
India
6. ¡°Imagine a cancer cure
without the destructive side effects of chemotherapy.
This leader in pediatric research is doing just that.¡±