The document discusses the human microbiome, which consists of bacteria, fungi, viruses, and mites that live on and inside the human body. The microbiome contains more genes than the human genome and plays a key role in human health. The microbiome is found in various areas of the body like the gut and skin. A diverse microbiome is important for health, but modern lifestyles can disrupt microbial diversity and lead to dysbiosis and various disorders. The document emphasizes the importance of a healthy microbiome and suggests ways to support it through diet, lifestyle habits, and skincare products.
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microbiome.ppt
1. “Your Body is Hardly
Your Body”
Understanding Your Microbiome
by Sudhir M. Shah
2. My Commitment
? Expand your understanding
? Create a new paradigm
? Examine your beliefs
? You walk away with something of value
3. My Request
? Let’s make this session interactive
? Be generous with your participation
? Be open in your listening
? Try on new paradigm
4. Microbiota
? Consists of bacteria, fungi, viruses, mites
? More bacteria in our body than our own
cells.
? This microbiota has more genes than we
have.
? The microbiome refers to the collection
of genomes from all the microorganisms
5. Microbiome
? Although microbes
are so small that they
require a microscope
to see them, they
contribute in big
ways to human
health and wellness.
15. What is the skin microbiome?
? The skin microbiota is the term used
to describe the millions of different
organisms – bacteria, viruses and
fungi – that live on Human Skin.
The skin microbiome is the genetic
material of all these microbes.
16. Diverse Microbiome
? There are over 1,000 species of bacteria and
up to 80 different fungi specie on skin that
have been identified, with research ongoing
17. Chemical Induced Dysbiosis
? Exposure to external pathogens
? Increase in “bad” bacteria
? (Staphylococcus aureus, Pseudomonas,
cutibacterium acnes, etc.)
? Viral infections
18. Skin microbiome and skin
disease
? Myths
? Indoctrination
? Become your own advocate
19. Harmful to Skin Flora
? Over washing
? Antibacterial soaps
? Alkaline cleanser
? Alcohol and petrochemicals
? Abrasive exfoliation
? Preservatives
Who among us can identify themselves with this statement?
What does that realy mean?
The human genome project showed us that we only have 22,000 genes to perform and control our entire body and its tasks. That’s even lower than an earthworm who has over 30,000 genes. So how do we function? Our microbiome contributes additional over two million genes.
Our gut of course, but also our esophagus, stomach, colon, our skin, hair, nostrils, mouth, lungs, vagina
Intercommunication between the host and the gut microbiome. Gut microbes are known to communicate with the host in numerous ways including through the production of metabolites, the modulation of the immune system, and altering gut permeability. In turn, the host influences the gut microbiome in a variety of ways including altering the gut lumen environment through diet, and immune modulation.
The microbiome is implicated in a variety of disorders. Much recent research has found evidence for a role for the microbiome in many diseases including skin, metabolic, and cardiovascular disease, as well as cancer, infection, and neurodegenerative and psychiatric disorders
Fecal microbiota transplantation (FMT) as a therapy. Stool from a healthy donor is collected and screened for safety. Then, the FMT is given to the patient, sometimes after antibiotic-treated to wash out the old microbiota. The FMT restores host health by instating a microbiome similar to that of the healthy donor.