The document describes a learning alliance framework for facilitating collaboration between organizations. Key aspects of the framework include establishing clear shared objectives, differentiating but linking learning mechanisms, developing long-term trusting relationships, and engaging in iterative learning cycles of documenting knowledge, field applications, and using lessons to improve practices and influence policy and systems change. The framework has been applied through a learning alliance in Central America involving over 25 partner organizations and benefiting over 35,000 families.