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Musculature in
vertebrates
Presented by:-
Bhupen chandra koch
Roll no- 23
M.Sc 3rd
samester
Dept. of zoology
Gauhati university
The Muscular System
 Muscles are responsible for all movement
of the body
 There are three basic types of muscle
 Skeletal
 Cardiac
 Smooth
3 Types of Muscles
Three types of muscle
Skeletal Cardiac Smooth
Classification of Muscle
Skeletal-
found in limbs
Cardiac-
found in heart
Smooth-
Found in
viscera
Striated, multi-
nucleated
Striated, 1
nucleus
Not striated, 1
nucleus
voluntary involuntary involuntary
Characteristics of Muscle
 Skeletal and smooth muscle are elongated
 Muscle cell = muscle fiber
 Contraction of a muscle is due to movement
of microfilaments (protein fibers)
 All muscles share some terminology
 Prefixes myo and mys refer to muscle
 Prefix sarco refers to flesh
Shapes of Muscles
 Triangular- shoulder, neck
 Spindle- arms, legs
 Flat- diaphragm, forehead
 Circular- mouth, anus
Skeletal Muscle
 Most are attached by tendons to bones
 Cells have more than one nucleus
(multinucleated)
 Striated- have stripes, banding
 Voluntary- subject to conscious control
 Tendons are mostly made of collagen fibers
 Found in the limbs
 Produce movement, maintain posture,
generate heat, stabilize joints
Structure of skeletal muscle
 Each cell (fibre) is long and cylindrical
 Muscle fibres are multi-nucleated
 Typically 50-60mm in diameter, and up
to 10cm long
 The contractile elements of
skeletal muscle cells are
myofibrils
Skeletal muscle - Summary
 Voluntary movement
of skeletal parts
 Spans joints and
attached to skeleton
 Multi-nucleated,
striated, cylindrical
fibres
Smooth Muscle
 No striations
 Spindle shaped
 Single nucleus
 Involuntary- no conscious control
 Found mainly in the walls of hollow organs
Smooth muscle
 Lines walls of viscera
 Found in longitudinal or
circular arrangement
 Alternate contraction of
circular & longitudinal
muscle in the intestine
leads to peristalsis
Structure of smooth muscle
 Spindle shaped uni-nucleated cells
 Striations not observed
 Actin and myosin filaments are present(
protein fibers)
Smooth muscle - Summary
 Found in walls of
hollow internal
organs
 Involuntary
movement of
internal organs
 Elongated, spindle
shaped fibre with
single nucleus
Cardiac Muscle
 Striations
 Branching cells
 Involuntary
 Found only in the heart
 Usually has a single nucleus, but can have
more than one
Cardiac muscle
 Main muscle of heart
 Pumping mass of heart
 Critical in humans
 Heart muscle cells
behave as one unit
 Heart always contracts
to its full extent
Structure of cardiac muscle
 Cardiac muscle cells (fibres) are
short, branched and
interconnected
 Cells are striated & usually have 1
nucleus
 Adjacent cardiac cells are joined
via electrical synapses (gap
junctions)
 These gap junctions appear as
dark lines and are called
Cardiac muscle - Summary
 Found in the heart
 Involuntary rhythmic
contraction
 Branched, striated
fibre with single
nucleus and
intercalated discs
Muscle Control
Type of
muscle
Nervous
control
Type of
control
Example
SkeletalSkeletal Controlled
by CNS
Voluntary Lifting a
glass
Cardiac Regulated
by ANS
Involuntary Heart
beating
Smooth Controlled
by ANS
Involuntary Peristalsis
Types of Responses
 Twitch-
 A single brief contraction
 Not a normal muscle function
 Tetanus
 One contraction immediately followed by
another
 Muscle never completely returns to a relaxed
state
 Effects are compounded
Where Does the Energy Come
From?
 Energy is stored in the muscles in the form
of ATP
 ATP comes from the breakdown of glucose
during Cellular Respiration
 This all happens in the Mitochondria of the
cell
 When a muscle is fatigued (tired) it is
unable to contract because of lack of
Oxygen
How are Muscles Attached to
Bone?
 Origin-attachment to a movable bone
 Insertion- attachment to an immovable
bone
 Muscles are always attached to at least 2
points
 Movement is attained due to a muscle
moving an attached bone
Structure of Skeletal Muscle:
Microstructure
 Sarcolemma
 Muscle cell membrane
 Myofibrils
 Threadlike strands within muscle fibers
 Actin (thin filament)
 Troponin
 Tropomyosin
 Myosin (thick filament)
Musculature in                    vertebrates
Structure of Skeletal Muscle:
The Sarcomere
 Further divisions of myofibrils
 Z-line
 A-band
 I-band
 Within the sarcoplasm
 Sarcoplasmic reticulum
 Storage sites for calcium
 Transverse tubules
 Terminal cisternae
Sliding Filament Theory
 Rest  uncharged ATP cross-bridge complex
 Excitation-coupling  charged ATP cross-
bridge complex, turned on
 Contraction  actomyosin  ATP > ADP & Pi
+ energy
 Recharging  reload cross-bridge with ATP
 Relaxation  cross-bridges turned off
The Sliding Filament Model of
Muscle Contraction
Musculature in                    vertebrates
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Musculature in vertebrates

  • 1. Musculature in vertebrates Presented by:- Bhupen chandra koch Roll no- 23 M.Sc 3rd samester Dept. of zoology Gauhati university
  • 2. The Muscular System Muscles are responsible for all movement of the body There are three basic types of muscle Skeletal Cardiac Smooth
  • 3. 3 Types of Muscles
  • 4. Three types of muscle Skeletal Cardiac Smooth
  • 5. Classification of Muscle Skeletal- found in limbs Cardiac- found in heart Smooth- Found in viscera Striated, multi- nucleated Striated, 1 nucleus Not striated, 1 nucleus voluntary involuntary involuntary
  • 6. Characteristics of Muscle Skeletal and smooth muscle are elongated Muscle cell = muscle fiber Contraction of a muscle is due to movement of microfilaments (protein fibers) All muscles share some terminology Prefixes myo and mys refer to muscle Prefix sarco refers to flesh
  • 7. Shapes of Muscles Triangular- shoulder, neck Spindle- arms, legs Flat- diaphragm, forehead Circular- mouth, anus
  • 8. Skeletal Muscle Most are attached by tendons to bones Cells have more than one nucleus (multinucleated) Striated- have stripes, banding Voluntary- subject to conscious control Tendons are mostly made of collagen fibers Found in the limbs Produce movement, maintain posture, generate heat, stabilize joints
  • 9. Structure of skeletal muscle Each cell (fibre) is long and cylindrical Muscle fibres are multi-nucleated Typically 50-60mm in diameter, and up to 10cm long The contractile elements of skeletal muscle cells are myofibrils
  • 10. Skeletal muscle - Summary Voluntary movement of skeletal parts Spans joints and attached to skeleton Multi-nucleated, striated, cylindrical fibres
  • 11. Smooth Muscle No striations Spindle shaped Single nucleus Involuntary- no conscious control Found mainly in the walls of hollow organs
  • 12. Smooth muscle Lines walls of viscera Found in longitudinal or circular arrangement Alternate contraction of circular & longitudinal muscle in the intestine leads to peristalsis
  • 13. Structure of smooth muscle Spindle shaped uni-nucleated cells Striations not observed Actin and myosin filaments are present( protein fibers)
  • 14. Smooth muscle - Summary Found in walls of hollow internal organs Involuntary movement of internal organs Elongated, spindle shaped fibre with single nucleus
  • 15. Cardiac Muscle Striations Branching cells Involuntary Found only in the heart Usually has a single nucleus, but can have more than one
  • 16. Cardiac muscle Main muscle of heart Pumping mass of heart Critical in humans Heart muscle cells behave as one unit Heart always contracts to its full extent
  • 17. Structure of cardiac muscle Cardiac muscle cells (fibres) are short, branched and interconnected Cells are striated & usually have 1 nucleus Adjacent cardiac cells are joined via electrical synapses (gap junctions) These gap junctions appear as dark lines and are called
  • 18. Cardiac muscle - Summary Found in the heart Involuntary rhythmic contraction Branched, striated fibre with single nucleus and intercalated discs
  • 19. Muscle Control Type of muscle Nervous control Type of control Example SkeletalSkeletal Controlled by CNS Voluntary Lifting a glass Cardiac Regulated by ANS Involuntary Heart beating Smooth Controlled by ANS Involuntary Peristalsis
  • 20. Types of Responses Twitch- A single brief contraction Not a normal muscle function Tetanus One contraction immediately followed by another Muscle never completely returns to a relaxed state Effects are compounded
  • 21. Where Does the Energy Come From? Energy is stored in the muscles in the form of ATP ATP comes from the breakdown of glucose during Cellular Respiration This all happens in the Mitochondria of the cell When a muscle is fatigued (tired) it is unable to contract because of lack of Oxygen
  • 22. How are Muscles Attached to Bone? Origin-attachment to a movable bone Insertion- attachment to an immovable bone Muscles are always attached to at least 2 points Movement is attained due to a muscle moving an attached bone
  • 23. Structure of Skeletal Muscle: Microstructure Sarcolemma Muscle cell membrane Myofibrils Threadlike strands within muscle fibers Actin (thin filament) Troponin Tropomyosin Myosin (thick filament)
  • 25. Structure of Skeletal Muscle: The Sarcomere Further divisions of myofibrils Z-line A-band I-band Within the sarcoplasm Sarcoplasmic reticulum Storage sites for calcium Transverse tubules Terminal cisternae
  • 26. Sliding Filament Theory Rest uncharged ATP cross-bridge complex Excitation-coupling charged ATP cross- bridge complex, turned on Contraction actomyosin ATP > ADP & Pi + energy Recharging reload cross-bridge with ATP Relaxation cross-bridges turned off
  • 27. The Sliding Filament Model of Muscle Contraction