This document summarizes the three main types of muscle in vertebrates: skeletal, cardiac, and smooth muscle. Skeletal muscle is striated and voluntary, found in limbs, and produces movement. Cardiac muscle is also striated but involuntary, found only in the heart. Smooth muscle is not striated, involuntary, and found in internal organs. The document describes the structure, function, and characteristics of each muscle type in more detail. It also discusses muscle control and how muscles generate force through the sliding filament model of contraction.
5. Classification of Muscle
Skeletal-
found in limbs
Cardiac-
found in heart
Smooth-
Found in
viscera
Striated, multi-
nucleated
Striated, 1
nucleus
Not striated, 1
nucleus
voluntary involuntary involuntary
6. Characteristics of Muscle
Skeletal and smooth muscle are elongated
Muscle cell = muscle fiber
Contraction of a muscle is due to movement
of microfilaments (protein fibers)
All muscles share some terminology
Prefixes myo and mys refer to muscle
Prefix sarco refers to flesh
7. Shapes of Muscles
Triangular- shoulder, neck
Spindle- arms, legs
Flat- diaphragm, forehead
Circular- mouth, anus
8. Skeletal Muscle
Most are attached by tendons to bones
Cells have more than one nucleus
(multinucleated)
Striated- have stripes, banding
Voluntary- subject to conscious control
Tendons are mostly made of collagen fibers
Found in the limbs
Produce movement, maintain posture,
generate heat, stabilize joints
9. Structure of skeletal muscle
Each cell (fibre) is long and cylindrical
Muscle fibres are multi-nucleated
Typically 50-60mm in diameter, and up
to 10cm long
The contractile elements of
skeletal muscle cells are
myofibrils
10. Skeletal muscle - Summary
Voluntary movement
of skeletal parts
Spans joints and
attached to skeleton
Multi-nucleated,
striated, cylindrical
fibres
11. Smooth Muscle
No striations
Spindle shaped
Single nucleus
Involuntary- no conscious control
Found mainly in the walls of hollow organs
12. Smooth muscle
Lines walls of viscera
Found in longitudinal or
circular arrangement
Alternate contraction of
circular & longitudinal
muscle in the intestine
leads to peristalsis
13. Structure of smooth muscle
Spindle shaped uni-nucleated cells
Striations not observed
Actin and myosin filaments are present(
protein fibers)
14. Smooth muscle - Summary
Found in walls of
hollow internal
organs
Involuntary
movement of
internal organs
Elongated, spindle
shaped fibre with
single nucleus
15. Cardiac Muscle
Striations
Branching cells
Involuntary
Found only in the heart
Usually has a single nucleus, but can have
more than one
16. Cardiac muscle
Main muscle of heart
Pumping mass of heart
Critical in humans
Heart muscle cells
behave as one unit
Heart always contracts
to its full extent
17. Structure of cardiac muscle
Cardiac muscle cells (fibres) are
short, branched and
interconnected
Cells are striated & usually have 1
nucleus
Adjacent cardiac cells are joined
via electrical synapses (gap
junctions)
These gap junctions appear as
dark lines and are called
18. Cardiac muscle - Summary
Found in the heart
Involuntary rhythmic
contraction
Branched, striated
fibre with single
nucleus and
intercalated discs
19. Muscle Control
Type of
muscle
Nervous
control
Type of
control
Example
SkeletalSkeletal Controlled
by CNS
Voluntary Lifting a
glass
Cardiac Regulated
by ANS
Involuntary Heart
beating
Smooth Controlled
by ANS
Involuntary Peristalsis
20. Types of Responses
Twitch-
A single brief contraction
Not a normal muscle function
Tetanus
One contraction immediately followed by
another
Muscle never completely returns to a relaxed
state
Effects are compounded
21. Where Does the Energy Come
From?
Energy is stored in the muscles in the form
of ATP
ATP comes from the breakdown of glucose
during Cellular Respiration
This all happens in the Mitochondria of the
cell
When a muscle is fatigued (tired) it is
unable to contract because of lack of
Oxygen
22. How are Muscles Attached to
Bone?
Origin-attachment to a movable bone
Insertion- attachment to an immovable
bone
Muscles are always attached to at least 2
points
Movement is attained due to a muscle
moving an attached bone
25. Structure of Skeletal Muscle:
The Sarcomere
Further divisions of myofibrils
Z-line
A-band
I-band
Within the sarcoplasm
Sarcoplasmic reticulum
Storage sites for calcium
Transverse tubules
Terminal cisternae
26. Sliding Filament Theory
Rest uncharged ATP cross-bridge complex
Excitation-coupling charged ATP cross-
bridge complex, turned on
Contraction actomyosin ATP > ADP & Pi
+ energy
Recharging reload cross-bridge with ATP
Relaxation cross-bridges turned off