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Nasal Polyp
Consulent
dr. Amran Simajuntak, Sp. THT-KL
Author:
Syahnita Mawarni LH
Nuraini Syahputri
Aulia Dini R
The Anatomy of
human nose
The Outside
Nose is
formed by the
hard bones
and cartilage
which layered
by connective
tissue and
small muscles
The Anatomy of
human nose
The Anatomy of
human nose
The Anatomy of
human nose
the medial wall of the septum is
formed by hard bone and cartilage
Hard bone :
-Lamina perpendikularis
-Vomer
-Krista nasalis os maksila
-Krista nasalis os palatina
Cartilage:
-cartilago septum
-kuadrangularis
-Kolumela
The Anatomy of
human nose
The Lateral wall is formed by :
 Konka
 Inferior
 Media
 Superior
nasal polyp fix 2 koass haji tht 2016 pptx
The Anatomy of
human nose
Meatus
- inferior : there is an estuary
of nasolaclimary duct
- media : estuary of frontal sinus,
maxillary sinus, etmoid anterior sinus
- Superior : estuary of etmoid posterior
sinus and sfenoid sinus
The Anatomy of
human nose
The border of nasal cavity :
-Inferior : formed by Os Maxilla and Os Palatum
-Nasal Palate : formed by lamina kribiformis
(part of Os Etmoid)
- Posterior : formed by Os Sfenoid
The Anatomy of
human nose
Nasal Vascularization
-Upper part : Etmoid
anterior artery and
posterior (branch of
artery ophtalmica hich
is part from interna
carotis artery)
-The front part :
facialis artery
-The front septum part :
pleksus kiesselbach
The Anatomy of
human nose
The nasal vein vascularization generally
follow the arterial pattern.
The vein have no vessel-valve
The Physiology of
Human Nose
 Providing airway for respiration
 Moistening (humidifying) and warming the
entering air
 Filtering inspired air and cleaning it of foreign
matter
 Serving as a resonating chamber for speech
 Housing the olfactory reseptor
Nasal Polyps
Benign mass that grow inside the
nasal cavity
Abnormal lesions that emanate from
portion of nasal mucosa or paranasal
sinuses
Most polyp grow from etmoidal sinus
mucose usually multiple or sometime
billateral.
nasal polyp fix 2 koass haji tht 2016 pptx
Nasal polyps
 Endoscopic view of left nasal
cavity. Polyp protruding from
uncinate process
Nasal polyps
 Left anterior nasal cavity
showing an antro-coanal polyp.
Sucker is pushing inferior
turbinate to one side
Clasification
Pathophysiology
 Unknown
 Chronic inflammation
 Autonomic nervous system dysfunction
 Genetic predisposition
 Allergic verses non-allergic
Pathophysiology
Associated with allergic conditions
 20-50% have asthma
 Allergic rhinitis
 8-26% have aspirin intolerance
 50% have alcohol intolerance
Pathophysiology
Non allergic conditions
 Cystic Fibrosis 6-48% have polyps
 AFS 85% have polyps
 Young syndrome
 Churg-Strauss syndrome
Pathophysiology
 Polyps are more common in patients with non-allergic
asthma (13%) than allergic asthma (5%)
 3000 atopic patients 0.5% have polyps
Norlander et al (1999)
Pathophysiology
Various theories
 Bernstein theory
 Vasomotor theory
 Epithelia rupture theory
Pathophysiology
Bernstein theory
 Inflammatory changes in lateral nasal wall or sinus
mucosa
 Polyps originate from contact area
 Ulceration, reepithelialisation and new gland formation
 Inflammatory processes from epithelial cells,
endothelium and fibroblasts
 Integrity of sodium channels affected
Frequency
 Adults 1-4%
 Children 0.1%
 All races and social classes
 M/F 2-4:1 in adults
 Increasing incidence with age
Clinical Manifestation
 Asymptomatic
 Airway obstruction
 Postnasal drip
 Dull headaches
 Snoring
 Rhinorhoea
 Hyposmia / Anosmia
 Epistaxis (often other lesion)
 Obstructive sleep apnoea
 Craniofacial abnormalities
 Optic nerve compression
Differential
 Encephalocoeles
 Gliomas
 Dermoid tumours
 Haemangiomas
 Papillomas / transitional cell papillomas
 Nasopharyngeal angiofibromas
 Rhabdomyosarcomas
 Lymphomas
 Neuroblastomas
 Sarcomas
 Chordomas
 Nasopharyngeal carcinomas
Investigations
 Sweat test
 RAST / skin testing
 Nasal smear
 Microbiology
 Eosinophils (allergic component)
 Neutrophils (chronic sinusitis)
Investigations
 Coronal CT scan
 MRI scan
 Flexible nasendoscopy
 Rigid nasendoscopy
Treatment
 Oral and nasal steroids
 High dose prednisolone and nasal steroid for 20 days will
eliminate 50% of polyps
 Lower bioavailability in modern nasal steroids
 Poor response in certain groups
 Intranasal injection not effective
 Immunotherapy
 Diet (no effect)
Treatment
 Traditional polypectomy
 Microdebrider
 Endoscopic sinus surgery
 Recurrence
 Multiple small polyps common
 Large and antro-coanal less so
Nasal polypectomy
 Nasal polyp. Stalk
attached to medial
maxillary wall
Nasal Polypectomy
 Microdebrider entering
left middle meatus
Summary
 Common condition in adults
 Aetiology not fully understood
 Majority are not allergic in nature
 Medical treatment can be effective
 Even with surgery, recurrence is common
Any questions?
nasal polyp fix 2 koass haji tht 2016 pptx

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nasal polyp fix 2 koass haji tht 2016 pptx

  • 1. Nasal Polyp Consulent dr. Amran Simajuntak, Sp. THT-KL Author: Syahnita Mawarni LH Nuraini Syahputri Aulia Dini R
  • 2. The Anatomy of human nose The Outside Nose is formed by the hard bones and cartilage which layered by connective tissue and small muscles
  • 5. The Anatomy of human nose the medial wall of the septum is formed by hard bone and cartilage Hard bone : -Lamina perpendikularis -Vomer -Krista nasalis os maksila -Krista nasalis os palatina Cartilage: -cartilago septum -kuadrangularis -Kolumela
  • 6. The Anatomy of human nose The Lateral wall is formed by : Konka Inferior Media Superior
  • 8. The Anatomy of human nose Meatus - inferior : there is an estuary of nasolaclimary duct - media : estuary of frontal sinus, maxillary sinus, etmoid anterior sinus - Superior : estuary of etmoid posterior sinus and sfenoid sinus
  • 9. The Anatomy of human nose The border of nasal cavity : -Inferior : formed by Os Maxilla and Os Palatum -Nasal Palate : formed by lamina kribiformis (part of Os Etmoid) - Posterior : formed by Os Sfenoid
  • 10. The Anatomy of human nose Nasal Vascularization -Upper part : Etmoid anterior artery and posterior (branch of artery ophtalmica hich is part from interna carotis artery) -The front part : facialis artery -The front septum part : pleksus kiesselbach
  • 11. The Anatomy of human nose The nasal vein vascularization generally follow the arterial pattern. The vein have no vessel-valve
  • 12. The Physiology of Human Nose Providing airway for respiration Moistening (humidifying) and warming the entering air Filtering inspired air and cleaning it of foreign matter Serving as a resonating chamber for speech Housing the olfactory reseptor
  • 13. Nasal Polyps Benign mass that grow inside the nasal cavity Abnormal lesions that emanate from portion of nasal mucosa or paranasal sinuses Most polyp grow from etmoidal sinus mucose usually multiple or sometime billateral.
  • 15. Nasal polyps Endoscopic view of left nasal cavity. Polyp protruding from uncinate process
  • 16. Nasal polyps Left anterior nasal cavity showing an antro-coanal polyp. Sucker is pushing inferior turbinate to one side
  • 18. Pathophysiology Unknown Chronic inflammation Autonomic nervous system dysfunction Genetic predisposition Allergic verses non-allergic
  • 19. Pathophysiology Associated with allergic conditions 20-50% have asthma Allergic rhinitis 8-26% have aspirin intolerance 50% have alcohol intolerance
  • 20. Pathophysiology Non allergic conditions Cystic Fibrosis 6-48% have polyps AFS 85% have polyps Young syndrome Churg-Strauss syndrome
  • 21. Pathophysiology Polyps are more common in patients with non-allergic asthma (13%) than allergic asthma (5%) 3000 atopic patients 0.5% have polyps Norlander et al (1999)
  • 22. Pathophysiology Various theories Bernstein theory Vasomotor theory Epithelia rupture theory
  • 23. Pathophysiology Bernstein theory Inflammatory changes in lateral nasal wall or sinus mucosa Polyps originate from contact area Ulceration, reepithelialisation and new gland formation Inflammatory processes from epithelial cells, endothelium and fibroblasts Integrity of sodium channels affected
  • 24. Frequency Adults 1-4% Children 0.1% All races and social classes M/F 2-4:1 in adults Increasing incidence with age
  • 25. Clinical Manifestation Asymptomatic Airway obstruction Postnasal drip Dull headaches Snoring Rhinorhoea Hyposmia / Anosmia Epistaxis (often other lesion) Obstructive sleep apnoea Craniofacial abnormalities Optic nerve compression
  • 26. Differential Encephalocoeles Gliomas Dermoid tumours Haemangiomas Papillomas / transitional cell papillomas Nasopharyngeal angiofibromas Rhabdomyosarcomas Lymphomas Neuroblastomas Sarcomas Chordomas Nasopharyngeal carcinomas
  • 27. Investigations Sweat test RAST / skin testing Nasal smear Microbiology Eosinophils (allergic component) Neutrophils (chronic sinusitis)
  • 28. Investigations Coronal CT scan MRI scan Flexible nasendoscopy Rigid nasendoscopy
  • 29. Treatment Oral and nasal steroids High dose prednisolone and nasal steroid for 20 days will eliminate 50% of polyps Lower bioavailability in modern nasal steroids Poor response in certain groups Intranasal injection not effective Immunotherapy Diet (no effect)
  • 30. Treatment Traditional polypectomy Microdebrider Endoscopic sinus surgery Recurrence Multiple small polyps common Large and antro-coanal less so
  • 31. Nasal polypectomy Nasal polyp. Stalk attached to medial maxillary wall
  • 32. Nasal Polypectomy Microdebrider entering left middle meatus
  • 33. Summary Common condition in adults Aetiology not fully understood Majority are not allergic in nature Medical treatment can be effective Even with surgery, recurrence is common