5. The Anatomy of
human nose
the medial wall of the septum is
formed by hard bone and cartilage
Hard bone :
-Lamina perpendikularis
-Vomer
-Krista nasalis os maksila
-Krista nasalis os palatina
Cartilage:
-cartilago septum
-kuadrangularis
-Kolumela
6. The Anatomy of
human nose
The Lateral wall is formed by :
Konka
Inferior
Media
Superior
8. The Anatomy of
human nose
Meatus
- inferior : there is an estuary
of nasolaclimary duct
- media : estuary of frontal sinus,
maxillary sinus, etmoid anterior sinus
- Superior : estuary of etmoid posterior
sinus and sfenoid sinus
9. The Anatomy of
human nose
The border of nasal cavity :
-Inferior : formed by Os Maxilla and Os Palatum
-Nasal Palate : formed by lamina kribiformis
(part of Os Etmoid)
- Posterior : formed by Os Sfenoid
10. The Anatomy of
human nose
Nasal Vascularization
-Upper part : Etmoid
anterior artery and
posterior (branch of
artery ophtalmica hich
is part from interna
carotis artery)
-The front part :
facialis artery
-The front septum part :
pleksus kiesselbach
11. The Anatomy of
human nose
The nasal vein vascularization generally
follow the arterial pattern.
The vein have no vessel-valve
12. The Physiology of
Human Nose
Providing airway for respiration
Moistening (humidifying) and warming the
entering air
Filtering inspired air and cleaning it of foreign
matter
Serving as a resonating chamber for speech
Housing the olfactory reseptor
13. Nasal Polyps
Benign mass that grow inside the
nasal cavity
Abnormal lesions that emanate from
portion of nasal mucosa or paranasal
sinuses
Most polyp grow from etmoidal sinus
mucose usually multiple or sometime
billateral.
21. Pathophysiology
Polyps are more common in patients with non-allergic
asthma (13%) than allergic asthma (5%)
3000 atopic patients 0.5% have polyps
Norlander et al (1999)
23. Pathophysiology
Bernstein theory
Inflammatory changes in lateral nasal wall or sinus
mucosa
Polyps originate from contact area
Ulceration, reepithelialisation and new gland formation
Inflammatory processes from epithelial cells,
endothelium and fibroblasts
Integrity of sodium channels affected
24. Frequency
Adults 1-4%
Children 0.1%
All races and social classes
M/F 2-4:1 in adults
Increasing incidence with age
29. Treatment
Oral and nasal steroids
High dose prednisolone and nasal steroid for 20 days will
eliminate 50% of polyps
Lower bioavailability in modern nasal steroids
Poor response in certain groups
Intranasal injection not effective
Immunotherapy
Diet (no effect)
30. Treatment
Traditional polypectomy
Microdebrider
Endoscopic sinus surgery
Recurrence
Multiple small polyps common
Large and antro-coanal less so
33. Summary
Common condition in adults
Aetiology not fully understood
Majority are not allergic in nature
Medical treatment can be effective
Even with surgery, recurrence is common