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Annexures
INTENSIFIED MISSION INDRADHANUSH 5.0 OPERATIONAL GUIDELINES
79
Draft
National Immunization Schedule (NIS) for Infants, Children and
Pregnant Women (Vaccine-wise)
Vaccine When to give Dose Route Site
For Pregnant Women
Tetanus & adult
Diphtheria
(Td)-1
Early in
pregnancy
0.5 ml
Intra-
muscular
Upper Arm
Td-2
4 weeks after
Td-1
0.5 ml
Intra-
muscular
Upper Arm
Td- Booster
If received 2
Td doses in
a pregnancy
within the last 3
yrs*
0.5 ml
Intra-
muscular
Upper Arm
For Infants
Bacillus
Calmette Guerin
(BCG)
At birth or as
early as possible
till one year of
age
0.1ml (0.05ml until 1
month age)
Intra-
dermal
Left Upper Arm
Hepatitis B -
Birth dose
At birth or as
early as possible
within 24 hours
0.5 ml
Intra-
muscular
Antero-lateral aspect of
mid-thigh
Oral Polio
Vaccine (OPV)-0
At birth or as
early as possible
within the first
15 days
2 drops Oral Oral (Mouth)
OPV 1, 2 & 3
At 6 weeks,
10 weeks & 14
weeks (OPV can
be given till 5
years of age)
2 drops Oral Oral (Mouth)
Pentavalent 1,
2 & 3
At 6 weeks,
10 weeks & 14
weeks (Penta-1
can be given till
one year of age)
0.5 ml
Intra-
muscular
Antero-lateral aspect of
left mid-thigh
Pneumococcal
Conjugate
Vaccine (PCV)
Two primary
doses at 6 and 14
weeks followed
by Booster dose
at 9-12 months.
0.5 ml
Intra-
muscular
Antero-lateral aspect of
right mid-thigh
In places where JE
vaccine is administered,
PCV Booster is to be
given on antero-lateral
aspect of left mid-thigh
Rotavirus (RVV)
At 6 weeks,
10 weeks & 14
weeks (RVV-1
can be given till
one year of age)
Rotavac: 5 drops
(liquid vaccine)
- open vial policy
Rotasil Liquid- 2ml -
single dose tubes
Oral Oral (Mouth)
Annexures
INTENSIFIED MISSION INDRADHANUSH 5.0 OPERATIONAL GUIDELINES 80
Draft
Vaccine When to give Dose Route Site
For Infants
Inactivated
Polio Vaccine
(IPV)
Three fractional
doses at 6, 14
weeks of age &
9-12 months of
age
0.1 ml
Intradermal
three
fractional
dose
fIPV-1 & fIPV 2-
Intradermal: Right
upper arm
fIPV-3 Intradermal: Left
upper arm
Measles Rubella
(MR) 1st dose
9 completed
months-12
months. (Can be
given till 5 years
of age)
0.5 ml
Sub-
cutaneous
Right Upper Arm
Japanese
Encephalitis
(JE) - 1**(Killed
vaccine)
9 completed
months-12
months.
0.5 ml
Intra-
muscular
Anterolateral aspect of
right mid thigh
Vitamin A (1st
dose)
At 9 completed
months with
Measles-Rubella
1 ml (1 lakh IU) Oral Oral
For Children
Diphtheria,
Pertussis &
Tetanus (DPT)
booster-1
16-24 months 0.5 ml
Intra-
muscular
Antero-lateral aspect of
left mid-thigh
MR 2nd dose 16-24 months 0.5 ml
Sub-
cutaneous
Right upper Arm
OPV Booster 16-24 months 2 drops Oral Oral (Mouth)
JE-2 (Killed
vaccine)
16-24 months 0.5 ml
Intra-
muscular
Antero-lateral aspect of
right mid thigh
Vitamin A***
(2nd to 9th
dose)
16-18 months.
Then one dose
every 6 months
up to the age of 5
years.
2 ml (2 lakh IU) Oral Oral (Mouth)
DPT Booster-2 5-6 years 0.5 ml.
Intra-
muscular
Left Upper Arm
Td
10 years & 16
years
0.5 ml
Intra-
muscular
Upper Arm
*One dose if previously vaccinated within 3 years
**JE Vaccine is introduced in select endemic districts after the campaign

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  • 1. Annexures INTENSIFIED MISSION INDRADHANUSH 5.0 OPERATIONAL GUIDELINES 79 Draft National Immunization Schedule (NIS) for Infants, Children and Pregnant Women (Vaccine-wise) Vaccine When to give Dose Route Site For Pregnant Women Tetanus & adult Diphtheria (Td)-1 Early in pregnancy 0.5 ml Intra- muscular Upper Arm Td-2 4 weeks after Td-1 0.5 ml Intra- muscular Upper Arm Td- Booster If received 2 Td doses in a pregnancy within the last 3 yrs* 0.5 ml Intra- muscular Upper Arm For Infants Bacillus Calmette Guerin (BCG) At birth or as early as possible till one year of age 0.1ml (0.05ml until 1 month age) Intra- dermal Left Upper Arm Hepatitis B - Birth dose At birth or as early as possible within 24 hours 0.5 ml Intra- muscular Antero-lateral aspect of mid-thigh Oral Polio Vaccine (OPV)-0 At birth or as early as possible within the first 15 days 2 drops Oral Oral (Mouth) OPV 1, 2 & 3 At 6 weeks, 10 weeks & 14 weeks (OPV can be given till 5 years of age) 2 drops Oral Oral (Mouth) Pentavalent 1, 2 & 3 At 6 weeks, 10 weeks & 14 weeks (Penta-1 can be given till one year of age) 0.5 ml Intra- muscular Antero-lateral aspect of left mid-thigh Pneumococcal Conjugate Vaccine (PCV) Two primary doses at 6 and 14 weeks followed by Booster dose at 9-12 months. 0.5 ml Intra- muscular Antero-lateral aspect of right mid-thigh In places where JE vaccine is administered, PCV Booster is to be given on antero-lateral aspect of left mid-thigh Rotavirus (RVV) At 6 weeks, 10 weeks & 14 weeks (RVV-1 can be given till one year of age) Rotavac: 5 drops (liquid vaccine) - open vial policy Rotasil Liquid- 2ml - single dose tubes Oral Oral (Mouth)
  • 2. Annexures INTENSIFIED MISSION INDRADHANUSH 5.0 OPERATIONAL GUIDELINES 80 Draft Vaccine When to give Dose Route Site For Infants Inactivated Polio Vaccine (IPV) Three fractional doses at 6, 14 weeks of age & 9-12 months of age 0.1 ml Intradermal three fractional dose fIPV-1 & fIPV 2- Intradermal: Right upper arm fIPV-3 Intradermal: Left upper arm Measles Rubella (MR) 1st dose 9 completed months-12 months. (Can be given till 5 years of age) 0.5 ml Sub- cutaneous Right Upper Arm Japanese Encephalitis (JE) - 1**(Killed vaccine) 9 completed months-12 months. 0.5 ml Intra- muscular Anterolateral aspect of right mid thigh Vitamin A (1st dose) At 9 completed months with Measles-Rubella 1 ml (1 lakh IU) Oral Oral For Children Diphtheria, Pertussis & Tetanus (DPT) booster-1 16-24 months 0.5 ml Intra- muscular Antero-lateral aspect of left mid-thigh MR 2nd dose 16-24 months 0.5 ml Sub- cutaneous Right upper Arm OPV Booster 16-24 months 2 drops Oral Oral (Mouth) JE-2 (Killed vaccine) 16-24 months 0.5 ml Intra- muscular Antero-lateral aspect of right mid thigh Vitamin A*** (2nd to 9th dose) 16-18 months. Then one dose every 6 months up to the age of 5 years. 2 ml (2 lakh IU) Oral Oral (Mouth) DPT Booster-2 5-6 years 0.5 ml. Intra- muscular Left Upper Arm Td 10 years & 16 years 0.5 ml Intra- muscular Upper Arm *One dose if previously vaccinated within 3 years **JE Vaccine is introduced in select endemic districts after the campaign