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Needle free injection-ppt

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kaushikbandopadhyay
kaushikbandopadhyay

No more fear from Injections! Discover it now! Felt nostalgic when Business Today published an article regarding the necessity and usefulness of Needlefree injections. Most probably it was published on May 10, 2013. He is the link: http://businesstoday.intoday.in/story/small-pharma-companies-in-niche-areas-of-health-care/1/194279.html

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NEEDLE FREE INJECTION By Kaushik Bandopadhyay NSEC, BME
CLASSIFICATION Needle free Injections can be classified into two types based on their mechanism of drug delivery: 1) Nano-Patch 2) Jet Pressure Needle free Injection
NANO-PATCH The most modern form of drug delivery through needle free system. As the name suggests, this is a small sized device having the size of a stamp which has about 20,000 micro-projections per square cm on its surface.
Needle free injection-ppt
Application Methods Drug delivery through Nano-Patch is done in two ways: 1) Sand paper aided delivery 2) Iontophoresis enabled delivery
Sand paper aided delivery
Mechanism of Operation The micro-projections containing drug/vaccine delivers the drug/vaccine into the epidermis. The epidermis is rich of Langerhans cells which are members of our Immune system These cells move to the nearest Lymph node and display the antigen to the T-cells
T-cells specifically recognizes one type of antigen and creates a corresponding antibody. Once this recognition procedure is completed the antibodies will provide immediate protection and these cells will protect from getting the same disease twice. Thereby providing life term of protection.
Needle free injection-ppt
Jet Pressured Needle free Injection Devised in the year 2001 by The Medical House and Bioject. This device has a specialized nozzle through which the drug is delivered. A three component system comprising an injection device, specially desgned nozzle and air cartridge is present.
Needle free injection-ppt
Mechanism of Operation Instead of creating a puncture on the skin surface, this device forces the drug through skin pores by the help of air pressure, thereby effectively delivering the drug without the help of needle.
Needle free injection-ppt
Advantages of using this technology Painless procedure Relief to patients who have to be inoculated many times in a day Efficient use of Vaccine Pandemic effective Zero contamination Better drug diffusion Zero disposal Hazard Ideal for developing countries
Popular Brands present Internationally Biojectorr 2000 Vitajet 3 Cool click Serojet Iject Biovalves Miniject
Limitation of this technology High pressure enabled delivery of drugs by the Jet Pressured Needle free Injection can damage fragile molecules beneath our skin surface, especially the Monoclonal antibodies.
Conclusion Is the future Needle-free? Developed countries have a Yes for this question while from developing countries the answer is not clear. Although this technology is designed for such nations, until a big pharmaceutical or biotechnology company adopts it here, it will continue to remain as a dream.
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Needle free injection-ppt

  • 2. CLASSIFICATION Needle free Injections can be classified into two types based on their mechanism of drug delivery: 1) Nano-Patch 2) Jet Pressure Needle free Injection
  • 3. NANO-PATCH The most modern form of drug delivery through needle free system. As the name suggests, this is a small sized device having the size of a stamp which has about 20,000 micro-projections per square cm on its surface.
  • 5. Application Methods Drug delivery through Nano-Patch is done in two ways: 1) Sand paper aided delivery 2) Iontophoresis enabled delivery
  • 6. Sand paper aided delivery
  • 7. Mechanism of Operation The micro-projections containing drug/vaccine delivers the drug/vaccine into the epidermis. The epidermis is rich of Langerhans cells which are members of our Immune system These cells move to the nearest Lymph node and display the antigen to the T-cells
  • 8. T-cells specifically recognizes one type of antigen and creates a corresponding antibody. Once this recognition procedure is completed the antibodies will provide immediate protection and these cells will protect from getting the same disease twice. Thereby providing life term of protection.
  • 10. Jet Pressured Needle free Injection Devised in the year 2001 by The Medical House and Bioject. This device has a specialized nozzle through which the drug is delivered. A three component system comprising an injection device, specially desgned nozzle and air cartridge is present.
  • 12. Mechanism of Operation Instead of creating a puncture on the skin surface, this device forces the drug through skin pores by the help of air pressure, thereby effectively delivering the drug without the help of needle.
  • 14. Advantages of using this technology Painless procedure Relief to patients who have to be inoculated many times in a day Efficient use of Vaccine Pandemic effective Zero contamination Better drug diffusion Zero disposal Hazard Ideal for developing countries
  • 15. Popular Brands present Internationally Biojectorr 2000 Vitajet 3 Cool click Serojet Iject Biovalves Miniject
  • 16. Limitation of this technology High pressure enabled delivery of drugs by the Jet Pressured Needle free Injection can damage fragile molecules beneath our skin surface, especially the Monoclonal antibodies.
  • 17. Conclusion Is the future Needle-free? Developed countries have a Yes for this question while from developing countries the answer is not clear. Although this technology is designed for such nations, until a big pharmaceutical or biotechnology company adopts it here, it will continue to remain as a dream.