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Neuroborreliosis vs multiple scelrosis

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Neuroborreliosis, also known as Lyme disease, is an infectious disease caused by the bacterium Borrelia burgdorferi, which can be transmitted to humans via tick bites. The document discusses the epidemiology, symptoms, complications, diagnosis, and treatment of neuroborreliosis. Symptoms may include flu-like symptoms, rashes, joint pain, and neurological problems. Diagnosis involves testing for antibodies in blood and spinal fluid. Treatment consists of antibiotics like doxycycline or amoxicillin. Prevention involves avoiding tick bites by using repellent and checking for ticks after being outdoors.

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Neuroborreliosis Name: Khalid Al-Kuwity ID:213119354 Tutor: DR. Ansari
Objectives Neuroborreliosis Epidemiology Complication Multiple Sclerosis Neuroborreliosis v.s M.S Diagnosis Clinical features Treatment Prevention
Neuroborreliosis Lyme disease (Neuroborreliosis ) is an infectious disease caused by the bacterium Borrelia burgdorferi . Lyme disease can be transmitted to humans by the bite of an infected tick.
What is Borreliosis? The genus Borrelia is a member of the larger family of spiral-shaped bacteria called Spirochaetes and the bacteria can be termed as a Borreliosis.
Cont There are many species of Borrelia bacteria worldwide, but not all of them cause the disease. There are only 3 species that known to cause the disease: 1- Borrelia burgdorferi. 2- Borrelia afzelii. 3- Borrelia garinii.
Symptoms Flu-like. Erythema migrans (EM) Rash. Headache. Stiff neck. Muscle pain. Tender glands sensitivity to temperature ,sound and light levels
遺看稼 Extreme tiredness. Muscle weakness. Joint pain. Upset digestive system. Disturbances of the central nervous system Sleep problems.
遺看稼
Epidemiology
Risk Factors Spending time in wooded or grassy areas. Having exposed skin. Not removing ticks promptly or properly.
Complications Chronic joint inflammation (Lyme arthritis) commonly in the knee. Neurological symptoms, such as facial palsy and neuropathy. Cognitive defects, such as impaired memory. Heart rhythm irregularities
Multiple Sclerosis
Neuroborreliosis v.s M.S
*Golden Key Mutable SclerosisLyme Disease Effect only the CNS UMN IgG oligoclonal band in the CSF Parathesia (transit) not sever pain and not persist Effect the CNS,PNS UMN, LMN Present with organism antibody ( IgM, IgG) in the CSF Sever burning pain
Diagnosis Clinical features. IgM antibodies detected in the 1st month. IgG late in the disease. Enzyme-linked immunosorbent assay (ELISA). CSF (cerebrospinal fluid). Polymerase chain reaction (PCR).
Clinical Features Skin stage :present with erythmea migrans. Associate with fever and headache Neurologic and cardiac stage Chronic Arthritis stage Several day to weeks or months If not treated
Neuroborreliosis vs multiple scelrosis
Treatment Antibacterial tablet ( Amoxicillin, doxycycline) Intravenous administration of ceftriaxone, cefotaxim or benzyl-pienicillin.
Prevention Wear long pants and long sleeves. Use insect repellents. Do your best to tick-proof your yard. Check yourself, your children and your pets for ticks. Don't assume you're immune. Remove a tick as soon as possible.
References 111-120, 130 1478-1481 352 156-161 http://www.mayoclinic.org/diseases- conditions/lyme-disease/basics. http://www.lymediseaseaction.org.uk
Neuroborreliosis vs multiple scelrosis
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Neuroborreliosis vs multiple scelrosis

  • 2. Objectives Neuroborreliosis Epidemiology Complication Multiple Sclerosis Neuroborreliosis v.s M.S Diagnosis Clinical features Treatment Prevention
  • 3. Neuroborreliosis Lyme disease (Neuroborreliosis ) is an infectious disease caused by the bacterium Borrelia burgdorferi . Lyme disease can be transmitted to humans by the bite of an infected tick.
  • 4. What is Borreliosis? The genus Borrelia is a member of the larger family of spiral-shaped bacteria called Spirochaetes and the bacteria can be termed as a Borreliosis.
  • 5. Cont There are many species of Borrelia bacteria worldwide, but not all of them cause the disease. There are only 3 species that known to cause the disease: 1- Borrelia burgdorferi. 2- Borrelia afzelii. 3- Borrelia garinii.
  • 6. Symptoms Flu-like. Erythema migrans (EM) Rash. Headache. Stiff neck. Muscle pain. Tender glands sensitivity to temperature ,sound and light levels
  • 7. 遺看稼 Extreme tiredness. Muscle weakness. Joint pain. Upset digestive system. Disturbances of the central nervous system Sleep problems.
  • 10. Risk Factors Spending time in wooded or grassy areas. Having exposed skin. Not removing ticks promptly or properly.
  • 11. Complications Chronic joint inflammation (Lyme arthritis) commonly in the knee. Neurological symptoms, such as facial palsy and neuropathy. Cognitive defects, such as impaired memory. Heart rhythm irregularities
  • 14. *Golden Key Mutable SclerosisLyme Disease Effect only the CNS UMN IgG oligoclonal band in the CSF Parathesia (transit) not sever pain and not persist Effect the CNS,PNS UMN, LMN Present with organism antibody ( IgM, IgG) in the CSF Sever burning pain
  • 15. Diagnosis Clinical features. IgM antibodies detected in the 1st month. IgG late in the disease. Enzyme-linked immunosorbent assay (ELISA). CSF (cerebrospinal fluid). Polymerase chain reaction (PCR).
  • 16. Clinical Features Skin stage :present with erythmea migrans. Associate with fever and headache Neurologic and cardiac stage Chronic Arthritis stage Several day to weeks or months If not treated
  • 18. Treatment Antibacterial tablet ( Amoxicillin, doxycycline) Intravenous administration of ceftriaxone, cefotaxim or benzyl-pienicillin.
  • 19. Prevention Wear long pants and long sleeves. Use insect repellents. Do your best to tick-proof your yard. Check yourself, your children and your pets for ticks. Don't assume you're immune. Remove a tick as soon as possible.
  • 20. References 111-120, 130 1478-1481 352 156-161 http://www.mayoclinic.org/diseases- conditions/lyme-disease/basics. http://www.lymediseaseaction.org.uk
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