This document discusses the hormonal control of the male reproductive system. It explains that the hypothalamus releases gonadotropin-releasing hormone (GnRH) which stimulates the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). FSH acts on Sertoli cells in the testes to support sperm production, while LH stimulates Leydig cells to secrete androgens like testosterone. Testosterone production is regulated by a negative feedback loop where high testosterone levels inhibit GnRH and FSH/LH secretion.