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nuclear envelope

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E
emicica

Nuclear receptors are located in the cell nucleus and respond to ligands by binding to specific DNA sequences to regulate gene transcription. They have several domains including a DNA binding domain that binds to DNA and a ligand binding domain that binds ligands to trigger a physiological response. Nuclear receptors play an important role in processes like development, metabolism and reproduction by controlling the expression of target genes.

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Nuclear receptors Emilie Lilford Group 11
Biochemical definition of a receptor
Chemical change physiological change biological function Ligand Receptor
Types of receptors and locations: Cell surface receptors Receptors located in the cytoplasm Nuclear receptors
Ligands of nuclear receptors
Structures of some nuclear receptor ligands and their corresponding receptors name.
Structural organization
nuclear envelope
Sandwich filling model of ligand binding domain (LBD) LBD
DNA binding domain (DBD) structure of the human progesterone receptor DBD
What is a Domain? Independent subunits of proteins. Between 25 -500 amino acids in length. Independently stable and folded. Can diverge and converge. Domain represents function.
Domains of nuclear receptors Zinc fingers LBD DBD N-terminal + C-terminal
How nuclear receptors work.
nuclear envelope

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