Operational boundaries of tablet Coating -film/enteric
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The document discusses the key factors involved in tablet coating processes, including inlet air and exhaust air properties, coating formulation characteristics like volatility and viscosity, spray system design elements such as gun design and spray rate, pan properties such as size and speed, and tablet core properties that influence coating such as size, shape, and surface roughness. All of these elements must be controlled and optimized to successfully produce film or enteric coatings on tablets within operational boundaries.
Operational boundaries of tablet Coating -film/enteric
- 1. Inlet air ? Volume ? Temperature ? Moisture control Exhaust Air ? Volume ? Temperature ? Moisture content Control system Coating formulation ? Volatility ? Tackiness ? Viscosity ? Surface tension ? Solid content ? Mechanical properties Spraying system ? Gun design ? Air cap design ? Fluid nozzle design-spray pattern ? Number of spray guns ? Angle of spray guns to tablet bed ? Distance of guns from tablet bed ? Spray rate ? Atomising air pressure /Volume ? Pattern air pressure/volume Coating pan ? Pan diameters ? Pan speed ? Tablet charging ? Bed porosity ? Surface area ? Mixing baffles ? Perforated area ? Bed temperature Tablet core ? Size ? Shape ? Hardness ? Friability ? Surface roughness ? Surface chemistry ? Tablet property Operation boundaries of tablet coating ¨C film / enteric s.gurubalaji@gmail.com