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Jose Miguel Alcantara
Jose Miguel Alcantara

This document provides information on the health benefits of oil of oregano as supported by both traditional use and recent scientific research. It summarizes that oregano oil has powerful antimicrobial, anti-inflammatory, and antioxidant properties. Specifically, it is effective against bacteria, fungi, yeasts, parasites, and even drug-resistant strains. These effects are due to active compounds like carvacrol and rosmarinic acid which damage cell membranes and reduce inflammation. Research also indicates oregano oil may help reduce risk of chronic diseases by protecting against free radical damage. The document recommends a dosage of 4 drops per day under the tongue or as directed by a healthcare practitioner.

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r e s e a r c h i n f o r m a t i o n This information is provided for educational purposes only, and is not intended for self-diagnosis or self-treatment of conditions that should be assessed and treated by your health care practitioner. While the information contained in this document has been carefully reviewed and reflects current clinical and scientific knowledge, it is subject to change. © All rights reserved – Natural Factors Nutritional Products Ltd. • Enquiries: custservice@naturalfactors.com • 39544 • September 4, 2009 • Pg 1 of 2 Where Great Health Begins Oil of oregano for your health Hippocrates, the father of scientific medicine, used oregano to prevent infections and to treat stomach and respiratory ailments. He advised, “Let food be your medicine.” This culin- ary herb, central to Mediterranean cuisine, has been receiving renewed scientific interest. Hundreds of studies have identified its active ingredients and confirmed their powerful synergistic effect in killing bacteria. Though Hippocrates was not aware of bacteria as the cause of infections, the healing power of the oregano’s volatile aromatic oils were well-known in antiquity. Many plants are called oregano, and the one sold for cooking in North America is usually a species from Mexico. But the oregano species with the proven healing properties is Origanum vulgare and grows wild in the mountains of Greece, Crete, Turkey and the Himalayas. Recent research has also discovered that oil of oregano has other powerful healing qualities. It is effective against yeast, parasites, and even the so-called “superbugs.” It is a potent anti-inflamma- tory and antioxidant, and can reduce the risk of several degene- rative diseases. The safety and effectiveness of oregano oil has been demonstrated by thousands of years of traditional use as a herbal remedy. Now, modern science confirms oil of oregano as an important natural health supplement. How oil of oregano works The antibacterial effects of oregano oil are likely due to its ability to penetrate cell membranes and disrupt their integrity. Studies have shown that if bacteria cells come into contact with oregano oil – or one of its active ingredients, carvacrol or thymol – then fluids leak out of the bacteria. The pH inside the bacteria also becomes more acidic, impairing metabolism and replication (Lambert). These findings are consistent with electron microscope observations that reveal damage to the cell membranes of bacteria exposed to oil of oregano. Pure, natural, and organic Natural Factors Certified Organic Oil of Oregano is derived from the wild-crafted Mediterranean oregano species Origanum vulgare. Carvacrol is the predominant phenol and most impor- tant component of wild oregano. The oil from Origanum vulgare has the highest naturally-occurring carvacrol content, at 80%. Brands that contain significantly more than 80% carvacrol are “spiked”, which may disturb the delicate synergistic balance of the individual phytochemicals as found in nature. By using the whole herb, rather than just some of its individual compounds, that synergy is maintained and potency greatly enhanced. The oregano oil in Natural Factors Certified Organic Oil of Oregano is guaranteed to contain 80% carvacrol. The oil is extracted from the hand-picked leaves using gentle steam distillation, ensuring that the oil is chemical free. Research shows that steam temperatures do not diminish the effectiveness of oregano oil. Pure oregano oil is too potent to be used full strength, so it is blended in a one-to-four ratio with olive oil. This is the ideal ratio for enabling the body to assimilate the oregano oil. Org- anic, cold-pressed, extra-virgin olive oil is used to ensure the product is 100% organic and free from chemical contaminants. The benefits of oil of oregano Research has shown oil of oregano has the following beneficial characteristics: • Antiseptic • Antibacterial • Antimicrobial • Antifungal • Antiparasitic • Anti-inflammatory • Antioxidant • Antimutagenic and anticarcinogenic • Analgesic (topical) Antimicrobial, antifungal, and antiparasitic As more and more antibiotic drugs lose their effectiveness against life-threatening bacterial infections, research is showing the oil of Origanum vulgare has potent antimicrobial actions that can give our immune systems some needed reinforcement. Many of oregano oil’s active constituents, including carvacrol and thymol, are phenolic compounds. They are responsible for oregano’s demonstrated ability to inhibit the growth of, or kill, many harmful microbes that infect humans. Several laboratory studies have shown oil of oregano to be effective against a range of problematic food-borne pathogens, including Escherichia coli O157:H7, Listeria monocytogenes, Salmonella typhimurium, and Staphylococcus aureus (Dadalioglu). Studies have also found oil of oregano to be effective against a variety of fungi and yeasts including Candida albicans, which becomes an infectious agent if there is a change in the body environment that allows it to grow out of control. In vitro research has shown that oregano oil completely stopped the growth of C. albicans in culture, inhibiting both its germina- tion and its mycelial growth. This effect was dose-dependent, meaning that the oregano oil was responsible for the effect (Manohar). certified organic oil of oregano Immune-enhancing, antimicrobial, and antioxidant
research information This information is provided for educational purposes only, and is not intended for self-diagnosis or self-treatment of conditions that should be assessed and treated by your health care practitioner. While the information contained in this document has been carefully reviewed and reflects current clinical and scientific knowledge, it is subject to change. © All rights reserved – Natural Factors Nutritional Products Ltd. • Enquiries: custservice@naturalfactors.com • 39544 • September 4, 2009 • Pg 2 of 2 Certified organic oil of oregano Significantly, researchers with the Uni- versity of West England recently found that oil of oregano is effective against the drug-resistant “superbugs” found in hospitals. They studied Origanum vulgare growing in the Himalayas and found its potent antibacterial properties were more effective than 18 antibiotic drugs. It killed the methicillin-resistant superbug Staphylococcus aureus even when diluted 1000:1 (Paddock). A human clinical trial also found daily supplementation with 600 mg of emul- sified oil of oregano completely elimi- nated a variety of intestinal parasites for most patients during a six-week treat- ment regime (Force). Anti-inflammatory Inflammation is part of the body’s nor- mal response to injury or infection. But sometimes inflammation can be exces- sive or unnecessary, and actually causes a disorder, such as certain cardiac condi- tions or seasonal allergies. Oil of oregano is rich in the polyphenol rosmarinic acid, which has been shown to have an anti-inflammatory action. In a human clinical trial, patients with sea- sonal allergies were treated daily with rosmarinic acid or a placebo for 21 days. Compared to placebo, supplementation with rosmarinic acid resulted in a signifi- cant improvement in symptoms. The researchers also investigated how the rosmarinic acid worked. They took nasal swabs from the patients and discovered the rosmarinic acid had decreased the number of neutrophils (the white blood cells that form the bulk of inflammatory congestion) and eosinophils, another type of white blood cell that produces harmful reactive oxygen species, inclu- ding free radicals (Osakabe). These natural anti-inflammatory effects of the active compounds in oil of ore- gano may be the basis for its historical use as a herbal remedy for inflammatory disorders, such as coughs, asthma, croup, bronchitis, rheumatoid arthritis, dys- pepsia, and dysmenorrhea. Anti-inflam- matory action may also underlie the use of oregano as a herbal remedy for acne, insect and spider bites, canker sores, gum disease, toothaches, psoriasis, seborrhea, rosacea, and muscle pain. Antioxidant Oil of oregano also provides effective antioxidant protection against cellular damage caused by free radicals. Free radicals oxidize some of the molecules that make up the body’s cells. This oxidation is a process similar to rusting and it damages the cells. Free radicals are a factor in inflammation and degenera- tive diseases, including arthritis, cancer, and heart disease. Oil of oregano contains powerful anti- oxidants such as rosmarinic acid and quercetin. A 2001 study of various medi- cinal herbs found that oil of oregano has an oxygen radical absorption capacity (ORAC) four times greater than blueber- ries, and at least 12 times that of oranges and other fruits and vegetables. Oregano’s ORAC value was higher than even vitamin E (Zheng). The ORAC test has become one of the standard methods to measure antioxidant properties in foods. The higher the ORAC value, the higher the concentration of antioxidants. In an animal study, pre-treatment with rosmarinic acid before exposure to a car- cinogenic chemical resulted in a reduc- tion in reactive oxygen species that cause free radical damage (Osakabe). Labora- tory tests showed the antioxidant com- pounds in oregano oil had a strong protective effect against the oxidation of LDL (“bad”) cholesterol, a key factor in heart disease (Kulisic). Some research has also found antimuta- genic and anticarcinogenic effects of oil of oregano, suggesting it may be useful in the prevention and treatment of cancer (Arcila-Lozano). Dosage Four drops daily directly under the tongue, mixed with water, applied topically, or as directed by a health care practitioner. A sensation of warmth is normal. Do not apply to raw or broken skin. Safety Oil of oregano (Origanum vulgare) is generally well-tolerated. Gastrointestinal upset may occur if the recommended dose is exceeded. If topical use is excessive, skin irritation or rashes may occur. Avoid contact with the eyes, and flush immediately with water if eye contact occurs. Pregnancy and lactation: Oil of oregano is not recommended during pregnancy or while breastfeeding. Children: Children under two years of age should not use oil of oregano topically or internally. Internal use by children 2 to 13 years old should be guided by a health care practitioner. Drug Interactions: As oil of oregano may contribute to blood thinning, consult a health care practitioner prior to use if you are taking blood-thinning medica- tions, aspirin, or NSAIDs. Contraindications: Use with caution if you are allergic to the lamiaceae family (inclu- ding basil, sage, mint, hyssop, lavender, thyme, rosemary, and other herbs). Used traditionally for thousands of years as a herbal remedy, the health benefits of oil of oregano are now supported by modern medical research. Oil of oregano can assist the immune system in com- bating an array of pathogenic microbes, improve inflammatory conditions, and reduce the risk of many degenerative diseases. Key REFERENCES Arcila-Lozano C.C., et al., “Oregano: properties, composition and biological activity”, Arch Latinoam Nutr, Mar; 54 (1): 100-11; 2004 Dadalioglu I., Evrendilek G.A., “Chemical compositions and antibacterial effects of essential oils of Turkish oregano (Origanum minutiflorum), bay laurel (Laurus nobilis), Spanish lavender (Lavandula stoechas L.), and fennel (Foeniculum vul- gare) on common foodborne pathogens”, J Agric Food Chem, Dec 29; 52 (26): 8255-60; 2004 Force M., et al., “Inhibition of enteric parasites by emulsified oil of oregano in vivo”, Phytotherapy Research, May; 14 (3): 213-214; 2000 Kulisic T., et al., “The effects of essential oils and aqueous tea infusions of oregano (Origanum vulgare L. spp. hirtum), thyme (Thymus vulgaris L.), and wild thyme (Thymus serphyllum L.) on the copper-induced oxidation of human low-density lipopro- teins”, Int J Food Sci Nutr, Mar; 58(2): 87-93; 2007 Lambert R.J., “A study of the minimum inhibitory concentra- tion and mode of action of oregano oil, thymol and carvacrol”, J Appl Microbiol, Sep; 91 (3): 453-62; 2001 Manohar V., et al., “Antifungal activities of origanum oil against Candida albicans”, Mol Cell Biochem, Dec; 228 (1-2): 111-7; 2001 Osakabe N., et al., “Anti-inflammatory and anti-allergy effects of rosmarinic acid (RA); inhibition of seasonal allergic rhinocon- junctivitis (SAR) and its mechanism”, Biofactors, 21 (1-4): 127-131; 2004 Paddock C., “Himalayan Oregano Effective Against MRSA”, Medical News Today, Nov 24; 2008 Zheng W., Wang S.Y., “Antioxidant activity and phenolic compounds in selected herbs”, J Agri Food Chem, 49 (11): 5165-70; 2001 Where Great Health Begins

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Opste informacije o ulju divljeg origana

  • 1. r e s e a r c h i n f o r m a t i o n This information is provided for educational purposes only, and is not intended for self-diagnosis or self-treatment of conditions that should be assessed and treated by your health care practitioner. While the information contained in this document has been carefully reviewed and reflects current clinical and scientific knowledge, it is subject to change. © All rights reserved – Natural Factors Nutritional Products Ltd. • Enquiries: custservice@naturalfactors.com • 39544 • September 4, 2009 • Pg 1 of 2 Where Great Health Begins Oil of oregano for your health Hippocrates, the father of scientific medicine, used oregano to prevent infections and to treat stomach and respiratory ailments. He advised, “Let food be your medicine.” This culin- ary herb, central to Mediterranean cuisine, has been receiving renewed scientific interest. Hundreds of studies have identified its active ingredients and confirmed their powerful synergistic effect in killing bacteria. Though Hippocrates was not aware of bacteria as the cause of infections, the healing power of the oregano’s volatile aromatic oils were well-known in antiquity. Many plants are called oregano, and the one sold for cooking in North America is usually a species from Mexico. But the oregano species with the proven healing properties is Origanum vulgare and grows wild in the mountains of Greece, Crete, Turkey and the Himalayas. Recent research has also discovered that oil of oregano has other powerful healing qualities. It is effective against yeast, parasites, and even the so-called “superbugs.” It is a potent anti-inflamma- tory and antioxidant, and can reduce the risk of several degene- rative diseases. The safety and effectiveness of oregano oil has been demonstrated by thousands of years of traditional use as a herbal remedy. Now, modern science confirms oil of oregano as an important natural health supplement. How oil of oregano works The antibacterial effects of oregano oil are likely due to its ability to penetrate cell membranes and disrupt their integrity. Studies have shown that if bacteria cells come into contact with oregano oil – or one of its active ingredients, carvacrol or thymol – then fluids leak out of the bacteria. The pH inside the bacteria also becomes more acidic, impairing metabolism and replication (Lambert). These findings are consistent with electron microscope observations that reveal damage to the cell membranes of bacteria exposed to oil of oregano. Pure, natural, and organic Natural Factors Certified Organic Oil of Oregano is derived from the wild-crafted Mediterranean oregano species Origanum vulgare. Carvacrol is the predominant phenol and most impor- tant component of wild oregano. The oil from Origanum vulgare has the highest naturally-occurring carvacrol content, at 80%. Brands that contain significantly more than 80% carvacrol are “spiked”, which may disturb the delicate synergistic balance of the individual phytochemicals as found in nature. By using the whole herb, rather than just some of its individual compounds, that synergy is maintained and potency greatly enhanced. The oregano oil in Natural Factors Certified Organic Oil of Oregano is guaranteed to contain 80% carvacrol. The oil is extracted from the hand-picked leaves using gentle steam distillation, ensuring that the oil is chemical free. Research shows that steam temperatures do not diminish the effectiveness of oregano oil. Pure oregano oil is too potent to be used full strength, so it is blended in a one-to-four ratio with olive oil. This is the ideal ratio for enabling the body to assimilate the oregano oil. Org- anic, cold-pressed, extra-virgin olive oil is used to ensure the product is 100% organic and free from chemical contaminants. The benefits of oil of oregano Research has shown oil of oregano has the following beneficial characteristics: • Antiseptic • Antibacterial • Antimicrobial • Antifungal • Antiparasitic • Anti-inflammatory • Antioxidant • Antimutagenic and anticarcinogenic • Analgesic (topical) Antimicrobial, antifungal, and antiparasitic As more and more antibiotic drugs lose their effectiveness against life-threatening bacterial infections, research is showing the oil of Origanum vulgare has potent antimicrobial actions that can give our immune systems some needed reinforcement. Many of oregano oil’s active constituents, including carvacrol and thymol, are phenolic compounds. They are responsible for oregano’s demonstrated ability to inhibit the growth of, or kill, many harmful microbes that infect humans. Several laboratory studies have shown oil of oregano to be effective against a range of problematic food-borne pathogens, including Escherichia coli O157:H7, Listeria monocytogenes, Salmonella typhimurium, and Staphylococcus aureus (Dadalioglu). Studies have also found oil of oregano to be effective against a variety of fungi and yeasts including Candida albicans, which becomes an infectious agent if there is a change in the body environment that allows it to grow out of control. In vitro research has shown that oregano oil completely stopped the growth of C. albicans in culture, inhibiting both its germina- tion and its mycelial growth. This effect was dose-dependent, meaning that the oregano oil was responsible for the effect (Manohar). certified organic oil of oregano Immune-enhancing, antimicrobial, and antioxidant
  • 2. research information This information is provided for educational purposes only, and is not intended for self-diagnosis or self-treatment of conditions that should be assessed and treated by your health care practitioner. While the information contained in this document has been carefully reviewed and reflects current clinical and scientific knowledge, it is subject to change. © All rights reserved – Natural Factors Nutritional Products Ltd. • Enquiries: custservice@naturalfactors.com • 39544 • September 4, 2009 • Pg 2 of 2 Certified organic oil of oregano Significantly, researchers with the Uni- versity of West England recently found that oil of oregano is effective against the drug-resistant “superbugs” found in hospitals. They studied Origanum vulgare growing in the Himalayas and found its potent antibacterial properties were more effective than 18 antibiotic drugs. It killed the methicillin-resistant superbug Staphylococcus aureus even when diluted 1000:1 (Paddock). A human clinical trial also found daily supplementation with 600 mg of emul- sified oil of oregano completely elimi- nated a variety of intestinal parasites for most patients during a six-week treat- ment regime (Force). Anti-inflammatory Inflammation is part of the body’s nor- mal response to injury or infection. But sometimes inflammation can be exces- sive or unnecessary, and actually causes a disorder, such as certain cardiac condi- tions or seasonal allergies. Oil of oregano is rich in the polyphenol rosmarinic acid, which has been shown to have an anti-inflammatory action. In a human clinical trial, patients with sea- sonal allergies were treated daily with rosmarinic acid or a placebo for 21 days. Compared to placebo, supplementation with rosmarinic acid resulted in a signifi- cant improvement in symptoms. The researchers also investigated how the rosmarinic acid worked. They took nasal swabs from the patients and discovered the rosmarinic acid had decreased the number of neutrophils (the white blood cells that form the bulk of inflammatory congestion) and eosinophils, another type of white blood cell that produces harmful reactive oxygen species, inclu- ding free radicals (Osakabe). These natural anti-inflammatory effects of the active compounds in oil of ore- gano may be the basis for its historical use as a herbal remedy for inflammatory disorders, such as coughs, asthma, croup, bronchitis, rheumatoid arthritis, dys- pepsia, and dysmenorrhea. Anti-inflam- matory action may also underlie the use of oregano as a herbal remedy for acne, insect and spider bites, canker sores, gum disease, toothaches, psoriasis, seborrhea, rosacea, and muscle pain. Antioxidant Oil of oregano also provides effective antioxidant protection against cellular damage caused by free radicals. Free radicals oxidize some of the molecules that make up the body’s cells. This oxidation is a process similar to rusting and it damages the cells. Free radicals are a factor in inflammation and degenera- tive diseases, including arthritis, cancer, and heart disease. Oil of oregano contains powerful anti- oxidants such as rosmarinic acid and quercetin. A 2001 study of various medi- cinal herbs found that oil of oregano has an oxygen radical absorption capacity (ORAC) four times greater than blueber- ries, and at least 12 times that of oranges and other fruits and vegetables. Oregano’s ORAC value was higher than even vitamin E (Zheng). The ORAC test has become one of the standard methods to measure antioxidant properties in foods. The higher the ORAC value, the higher the concentration of antioxidants. In an animal study, pre-treatment with rosmarinic acid before exposure to a car- cinogenic chemical resulted in a reduc- tion in reactive oxygen species that cause free radical damage (Osakabe). Labora- tory tests showed the antioxidant com- pounds in oregano oil had a strong protective effect against the oxidation of LDL (“bad”) cholesterol, a key factor in heart disease (Kulisic). Some research has also found antimuta- genic and anticarcinogenic effects of oil of oregano, suggesting it may be useful in the prevention and treatment of cancer (Arcila-Lozano). Dosage Four drops daily directly under the tongue, mixed with water, applied topically, or as directed by a health care practitioner. A sensation of warmth is normal. Do not apply to raw or broken skin. Safety Oil of oregano (Origanum vulgare) is generally well-tolerated. Gastrointestinal upset may occur if the recommended dose is exceeded. If topical use is excessive, skin irritation or rashes may occur. Avoid contact with the eyes, and flush immediately with water if eye contact occurs. Pregnancy and lactation: Oil of oregano is not recommended during pregnancy or while breastfeeding. Children: Children under two years of age should not use oil of oregano topically or internally. Internal use by children 2 to 13 years old should be guided by a health care practitioner. Drug Interactions: As oil of oregano may contribute to blood thinning, consult a health care practitioner prior to use if you are taking blood-thinning medica- tions, aspirin, or NSAIDs. Contraindications: Use with caution if you are allergic to the lamiaceae family (inclu- ding basil, sage, mint, hyssop, lavender, thyme, rosemary, and other herbs). Used traditionally for thousands of years as a herbal remedy, the health benefits of oil of oregano are now supported by modern medical research. Oil of oregano can assist the immune system in com- bating an array of pathogenic microbes, improve inflammatory conditions, and reduce the risk of many degenerative diseases. Key REFERENCES Arcila-Lozano C.C., et al., “Oregano: properties, composition and biological activity”, Arch Latinoam Nutr, Mar; 54 (1): 100-11; 2004 Dadalioglu I., Evrendilek G.A., “Chemical compositions and antibacterial effects of essential oils of Turkish oregano (Origanum minutiflorum), bay laurel (Laurus nobilis), Spanish lavender (Lavandula stoechas L.), and fennel (Foeniculum vul- gare) on common foodborne pathogens”, J Agric Food Chem, Dec 29; 52 (26): 8255-60; 2004 Force M., et al., “Inhibition of enteric parasites by emulsified oil of oregano in vivo”, Phytotherapy Research, May; 14 (3): 213-214; 2000 Kulisic T., et al., “The effects of essential oils and aqueous tea infusions of oregano (Origanum vulgare L. spp. hirtum), thyme (Thymus vulgaris L.), and wild thyme (Thymus serphyllum L.) on the copper-induced oxidation of human low-density lipopro- teins”, Int J Food Sci Nutr, Mar; 58(2): 87-93; 2007 Lambert R.J., “A study of the minimum inhibitory concentra- tion and mode of action of oregano oil, thymol and carvacrol”, J Appl Microbiol, Sep; 91 (3): 453-62; 2001 Manohar V., et al., “Antifungal activities of origanum oil against Candida albicans”, Mol Cell Biochem, Dec; 228 (1-2): 111-7; 2001 Osakabe N., et al., “Anti-inflammatory and anti-allergy effects of rosmarinic acid (RA); inhibition of seasonal allergic rhinocon- junctivitis (SAR) and its mechanism”, Biofactors, 21 (1-4): 127-131; 2004 Paddock C., “Himalayan Oregano Effective Against MRSA”, Medical News Today, Nov 24; 2008 Zheng W., Wang S.Y., “Antioxidant activity and phenolic compounds in selected herbs”, J Agri Food Chem, 49 (11): 5165-70; 2001 Where Great Health Begins