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Pharmacology-I
Oral Route of Drug Administration
SAMRUDDHI GAIKWAD
S.Y. B.Pharm
Routes of Drug Administration
Route of administration
Systemic Local
Enternal Parentral
Oral
Sublingual
Rectal
Inhalation
Injection
Skin Topical
Intranasal
Ocular drops
ORAL ROUTE.pptx
Oral Route
? It is the oldest and simplest route of
administration
? The drug is administered through
mouth.
? The main advantage of this route is
that the patient is able to self-
administer the drug.
Oral Route
? Mechanism of oral route is
complicated.
? Solid dosage forms such as powders,
tablets, capsules, etc. and liquid
dosage forms such as elixirs, syrups,
emulsions, etc. can be given through
oral route.
First Pass
Metabolism
? It is the hepatic metabolism of
drug when it is absorbed from
the intestine and then delivered
to the liver via the portal vein
Advantages of Oral Route
Safe, convenient
and painless
method therefore
most preferred.
Economical
Sterilization is not
required
No assistance is
required
Disadvantages of Oral Route
Sometimes complete drug is not absorbed
First-pass metabolism takes place
Not effective in emergencies
Not preferred for unconscious patients
Unpleasant taste of drug
Causes nausea and vomiting due to gastric mucosa irritation
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ORAL ROUTE.pptx

  • 1. Pharmacology-I Oral Route of Drug Administration SAMRUDDHI GAIKWAD S.Y. B.Pharm
  • 2. Routes of Drug Administration
  • 3. Route of administration Systemic Local Enternal Parentral Oral Sublingual Rectal Inhalation Injection Skin Topical Intranasal Ocular drops
  • 5. Oral Route ? It is the oldest and simplest route of administration ? The drug is administered through mouth. ? The main advantage of this route is that the patient is able to self- administer the drug.
  • 6. Oral Route ? Mechanism of oral route is complicated. ? Solid dosage forms such as powders, tablets, capsules, etc. and liquid dosage forms such as elixirs, syrups, emulsions, etc. can be given through oral route.
  • 7. First Pass Metabolism ? It is the hepatic metabolism of drug when it is absorbed from the intestine and then delivered to the liver via the portal vein
  • 8. Advantages of Oral Route Safe, convenient and painless method therefore most preferred. Economical Sterilization is not required No assistance is required
  • 9. Disadvantages of Oral Route Sometimes complete drug is not absorbed First-pass metabolism takes place Not effective in emergencies Not preferred for unconscious patients Unpleasant taste of drug Causes nausea and vomiting due to gastric mucosa irritation