際際滷

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Presented by: Dr. Ibdah
 65 year old patient ,female
 c/o : SOB, occasional palpitations
 TEE: ASD II , Left to Right Shunt. Diameter of
defect 14 mm . RV dilated with signs of volume
overloading
 Right heart Catheterization: PA sys 36mmHg
PVR 61 dyn/cm5
 Balloon sizing :
Percutaneous closure of atrial septal defect 3
 successful transcatheter ASD closure with
Amplazer device 22mm
 Common 3-10% of CHD
 Classification: ASD I, ASD II 70%, sinus venosus
 Female > Male
 Pathophsiology : initially left to right shunt
 Clinical features and diagnostic evaluation:
are not the scope of this presentation!
 Three questions crystallize the debate :
1. Who should have their ASD closed?
2. When should it be closed?
3. How should it be closed?
 Any patient with dilated RV or RA by Echo,MRT
or CT
 any ASD ( in the absence of of advanced
pulmonary HTN) with one or more of following:
1. ASD > 10 mm on TEE
2. Qp:Qs > 1.5:1
 Yes close it and yes do it as soon as possible !
 Is the age matter ? The answer is NO
 The defect too small follow them periodically
 Severe pulmonary arterial HTN ; do not close !
ASD acts here as ``pop-off`` valve
 Pregnancy  defer 6 months after delivery
 Severe LV dysfunction . Again ASD functioning
as`` pop-off`` valve
Percutaneous closure of atrial septal defect 3
 Device closure is a safe and effective procedure in
experienced hands
 Advantages of device closure :
less hospital stay, avoidance surgical wounds, same
hemodynamic benefit as by surgery
 Drawbacks: large defect > 36 mm, septal rim less
than 5 mm, proximity of defect to AV ,CS,IVC,SVC
Successful closure achieved in 95 % of Pt.
 Tachyarrhythmia 1-4% follow up , ablation
 Brady arrhythmia  Pacing
 Device migration and erosion : catastrophic but rare
0,1 %related to operator experience and over sizing
 Right heart failure or progressive pulmonary HTN ;
related to the age of patient at the time of closure
 Thrombosis 1.2 %: maximal at 4 weeks ,rare with
dual therapy era
 Nickel allergy ! Chest pain at next day  do skin test
if positive  remove the device
 Small: common after catheter closure ,close
spontaneously after 1 year
 Large : false measurement, dehisced
ASD device
 Dual antiplatelet therapy 6 months
 TTE next day .
 TEE in 1,6 and in 12 months
 IE-prophylaxis for 6 months
 Majority of ASD II are device closable
 Safe and effective procedure
 need for excellent pre-procedure work up
Thank you for your attention

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Percutaneous closure of atrial septal defect 3

  • 2. 65 year old patient ,female c/o : SOB, occasional palpitations TEE: ASD II , Left to Right Shunt. Diameter of defect 14 mm . RV dilated with signs of volume overloading Right heart Catheterization: PA sys 36mmHg PVR 61 dyn/cm5 Balloon sizing :
  • 4. successful transcatheter ASD closure with Amplazer device 22mm
  • 5. Common 3-10% of CHD Classification: ASD I, ASD II 70%, sinus venosus Female > Male Pathophsiology : initially left to right shunt Clinical features and diagnostic evaluation: are not the scope of this presentation!
  • 6. Three questions crystallize the debate : 1. Who should have their ASD closed? 2. When should it be closed? 3. How should it be closed?
  • 7. Any patient with dilated RV or RA by Echo,MRT or CT any ASD ( in the absence of of advanced pulmonary HTN) with one or more of following: 1. ASD > 10 mm on TEE 2. Qp:Qs > 1.5:1
  • 8. Yes close it and yes do it as soon as possible ! Is the age matter ? The answer is NO
  • 9. The defect too small follow them periodically Severe pulmonary arterial HTN ; do not close ! ASD acts here as ``pop-off`` valve Pregnancy defer 6 months after delivery Severe LV dysfunction . Again ASD functioning as`` pop-off`` valve
  • 11. Device closure is a safe and effective procedure in experienced hands Advantages of device closure : less hospital stay, avoidance surgical wounds, same hemodynamic benefit as by surgery Drawbacks: large defect > 36 mm, septal rim less than 5 mm, proximity of defect to AV ,CS,IVC,SVC
  • 12. Successful closure achieved in 95 % of Pt. Tachyarrhythmia 1-4% follow up , ablation Brady arrhythmia Pacing Device migration and erosion : catastrophic but rare 0,1 %related to operator experience and over sizing Right heart failure or progressive pulmonary HTN ; related to the age of patient at the time of closure Thrombosis 1.2 %: maximal at 4 weeks ,rare with dual therapy era Nickel allergy ! Chest pain at next day do skin test if positive remove the device
  • 13. Small: common after catheter closure ,close spontaneously after 1 year Large : false measurement, dehisced ASD device
  • 14. Dual antiplatelet therapy 6 months TTE next day . TEE in 1,6 and in 12 months IE-prophylaxis for 6 months
  • 15. Majority of ASD II are device closable Safe and effective procedure need for excellent pre-procedure work up
  • 16. Thank you for your attention