GlaxoSmithKline is focused on developing HIV therapies that minimize cumulative drug exposure for patients who must endure lifelong antiretroviral treatment. It believes the potency, safety and resistance barrier of dolutegravir combined with the efficacy, safety and tolerability of rilpivirine from Johnson & Johnson make them ideal candidates for a two-drug HIV regimen.
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11. GSK Focused On Minimizing Need For
Cumulative Drug Exposure
Glaxo is the second-largest HIV company, with revenue of about $5.2 billion versus Gilead's $12.9 billion.
Long-life antiretroviral therapy that the HIV infected have to endure has created a need to minimize cumulative
drug exposure. Glaxo wants to develop HIV therapies that meet that need. It believes the potency, safety and resistance
barrier of dolutegravir and the efficacy, safety and tolerability of Johnson & Johnson's (NYSE:JNJ) rilpivirine make
them ideal for a two-drug regimen.