Calcium supplements, vitamin D analogues, and phosphate binders are key pharmacological interventions to manage bone health in kidney disease by addressing hypocalcemia, regulating calcium and PTH levels, and controlling hyperphosphatemia. Additional treatments include calcimimetics to reduce PTH secretion, and bisphosphonates to prevent bone loss and fractures by strengthening bone. Regular monitoring and medication adjustments are important for renal osteodystrophy treatment.
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Pharmacological Treatment for Renal Osteodystrophy.pptx
2. Key Pharmacological Interventions
? Calcium Supplements: Used to address hypocalcemia and
prevent bone loss. Common medications include calcium
carbonate.
? Vitamin D Analogues: Regulate calcium absorption and
parathyroid hormone (PTH) levels. Examples include calcitriol
and paricalcitol.
? Phosphate Binders: Control hyperphosphatemia by binding to
3. Additional Pharmacological
Interventions
? Calcimimetics: Manage secondary hyperparathyroidism by
reducing PTH secretion. Cinacalcet is a common calcimimetic
medication.
? Bisphosphonates: Prevent bone loss and fractures in renal
osteodystrophy. Medications like alendronate and zoledronic
acid are used.
? Monitoring and Adjustments: Stress the importance of