This document discusses the stages and physiology of sleep. It defines sleep as a state of unconsciousness that one can be aroused from, and coma as a state of unconsciousness that one cannot be aroused from. It describes the four stages of non-rapid eye movement (NREM) sleep - stages 1, 2, 3, and 4 - as well as rapid eye movement (REM) sleep. It provides details on the EEG patterns, duration, and characteristics of each sleep stage. Overall, it provides a comprehensive overview of the stages and cycles of sleep.
2. Definitions
SLEEP:
A state of loss of consciousness form which a subject can
be aroused by appropriate stimulus.
COMA:
A state of unconsciousness form which a subject cannot be aroused.
6. STAGE 1 NREM
NREM (non-rapid eye movement) sleep is
dreamless sleep.
Occurs at sleep onset or following arousal form another
stage of sleep.
1 to 7 min in the initial cycle.
2 to 5% of total sleep.
Easily interupted
EEG: Rhythmic alpha wave.
7. STAGE 2 NREM
Lasts for 10 to 15 min in initial cycle and lengthens with
each successive cycle.
45 to 55% of total sleep duration.
Arousal requires more intense stimulus then stage 1.
EEG: Sleep spindles.
8. STAGE 3 NREM
Lasts only for a few minutes.
3-8% of total sleep.
EEG - High voltage, slow wave activity or delta wave
9. STAGE 4 NREM
Lasts 20-40 minutes in the first cycle.
10-15% of total sleep.
Arousal threshold is highest.
EEG - high voltage slow wave activity-delta waves.Together
with Stage 3 NREM - Slow Wave Sleep (SWS)
Now, combined with Stage 3 NREM into single entity-N3
Stage
11. REM
Desynchronised (low frequency) brain wave activity.
"Sawtooth" waveforms. Theta activity and slow alpha
activity also characterise REM sleep.
1-5 minutes in initial cycle.
Progressively prolonged as sleep progresses.
12. 4-5 cycles of these sequential stages
Each cycle -90-110 mins
As sleep progresses delta sleep decreases and REM sleep
increases.
REM in initial cycle is only 5-10 mins but in last cycle can
be as long as 40 mins
As sleep progresses Stage 2 predominates in NREM sleep
and Stage 3 & 4 sometimes disappear altogether.