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Platelets rich plasma for skin rejuvenation

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raditio ghifiardi
raditio ghifiardi

PRP is a breakthrough technique on skin care & treatment to preserve it's beauty & health at a very affordable cost and higher satisfactory result compared to other methods.

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NEW EVOLUTION OF AESTHETIC BIOTECHNOLOGYSPECIALIST IN NONABLATIVE SKIN REJUVENATION AND AUTOLOGOUS CELLULAR REGENERATIONIndah Yulianto.,Yulianto D., EndraYustin., Ari Kusumawardhani.DERMATO VENEREOLOGY DEPARTMENTMEDICAL FACULTY OF SEBELAS MARET UNIVERSITY / DR. MOEWARDI GENERAL HOSPITALSURAKARTA?
Skin treatment action levelsMultidisciplinary Program For the Rejuvenation for the faceFILLERSDermocoemeticisPeelsWrinkles & VolumescorrectionRenewal of the corneal layerBIO StimulationPRPGerminative layer stimulationDermis stimulationArchitectural skin reconstruction/reorganization
What is BEAUTY?Beauty is a balance between form and volumeBeauty produces in us an aesthetic feeling, an admiration by pleasing the eyeBeauty does not captivate through detail but through the whole,which is greater than the sum of the individual partsBeauty does not only have to do with the face, the voice, the body or a charming appearance.
Platelet-Rich Plasma (PRP)PRP has been breakthrough in the stimulation and acceleration of soft tissue healing, rejuevenationIt represents a relatively new biotechnology that is part of the growing interest in tissue engineering and cellular therapy todayThe clinically useful product is a concentration of platelets in small volume plasma and is therefore a ¡°platelet-rich-plasma¡±
It come drop by drop from our bloodAnatomy and Fungtion from platelets
PRP ¨C harvesting :Autologous Whole BloodRpm/minutesPlatelet poor plasma andBuffy coatErythrocytRpm/minutesThe patient¡¯s blood is drawnPlatelets Poor PlasmaPlatelets Rich PlasmaSteps in the preparation of platelet-rich plasma.Platelet-rich plasma (in the syringe) and platelet-poor plasma (in the centrifugation tube). The latter can be used to cover the surgical area.
HypothesisIf platelets concentrate could be brought to level greater than eight times baseline the physiological effects may be profoundly positive.(Dr Astley E Smith.,GlobalAutografting Institute)
PRP AND HC PRP
FIELDS APPLICATION of Platelets Rich Plasma
Some Growth Factors Acting on ¡°Healing Cascade¡± In addition the activated thrombocytes have onto their surface a multitude of signalisation molecules eg. CD9, CD-W17, CD31, CD41, CD42a-d, CD51, CD-W60, CD61, CD62P, CD63
Advantages of a-PlasmaTissue regeneration & rejuvenation: neo-collagenesis(TGF¦Á& ¦Â), neo-vascularisation(EGF & VEGF), & extracellularmatrix formation (PDGF¦Á¦Á& ¦Â¦Â& ¦Á¦Â) ¨CNB: growth factors in genetically pre-determined ratio!Bio-glue (fibrin glue): haemostasis & tissue adhesion in skin flaps, bone grafts, trauma intra-surgery and post-surgerySafety: non-allergenic & free from concerns over transmissible diseases e.g. HIV, Hepatitis B & C, CJD, etc.Autologous: no risk of rejection reactionWound healing time: increasedPhysiological ¡®anti-biotic¡¯: anti-bodies & WBC¡¯s& proteolyticenzymesPlasma includes: hormones, biotransformedvitamins & other nutrientsTissue engineering: in-vitro autologous tissue culture-medium.Ease of use: dermal & hypodermal injectionsConvenience: Plasma harvesting performed in doctor¡¯s rooms (no external laboratory required)
Platelets rich plasma for skin rejuvenation
Contra -IndicationsPlatelet Dysfunction SyndromeCritical ThrombocytopeniaHypofibrinogenaemiaHaemodynamicInstabilityAuto-immune diseaseMalignancySepsisAcute & Chronic InfectionsChronic Liver PathologyAnti-coagulation therapy Pregnancy (for cosmetic indications)
BEFORE1 Month After
AFTER ¨C 3 monthsBEFORE
A ¨C 64 years ¨C old woman, injection by autologous PRP1 month after.
After ¨C scratching by rat ¨C 3 weeks agoAcne Scar : Subcision + hc PRP : 1 month after
4 days after injectionsbefore
Acne Scar : Dermaroller 1.5 mm + PRP Before1 week after(right side)
Acne Scar + Subsicion + PRP 1 week afterSubsicion with NocorneedleBefore
3 weeks afterAlopecia ¨C 36 years old
Alopecia and Marking3 weeks after Injeksi PRPIn Bulbus
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Platelets rich plasma for skin rejuvenation

  • 1. NEW EVOLUTION OF AESTHETIC BIOTECHNOLOGYSPECIALIST IN NONABLATIVE SKIN REJUVENATION AND AUTOLOGOUS CELLULAR REGENERATIONIndah Yulianto.,Yulianto D., EndraYustin., Ari Kusumawardhani.DERMATO VENEREOLOGY DEPARTMENTMEDICAL FACULTY OF SEBELAS MARET UNIVERSITY / DR. MOEWARDI GENERAL HOSPITALSURAKARTA?
  • 2. Skin treatment action levelsMultidisciplinary Program For the Rejuvenation for the faceFILLERSDermocoemeticisPeelsWrinkles & VolumescorrectionRenewal of the corneal layerBIO StimulationPRPGerminative layer stimulationDermis stimulationArchitectural skin reconstruction/reorganization
  • 3. What is BEAUTY?Beauty is a balance between form and volumeBeauty produces in us an aesthetic feeling, an admiration by pleasing the eyeBeauty does not captivate through detail but through the whole,which is greater than the sum of the individual partsBeauty does not only have to do with the face, the voice, the body or a charming appearance.
  • 4. Platelet-Rich Plasma (PRP)PRP has been breakthrough in the stimulation and acceleration of soft tissue healing, rejuevenationIt represents a relatively new biotechnology that is part of the growing interest in tissue engineering and cellular therapy todayThe clinically useful product is a concentration of platelets in small volume plasma and is therefore a ¡°platelet-rich-plasma¡±
  • 5. It come drop by drop from our bloodAnatomy and Fungtion from platelets
  • 6. PRP ¨C harvesting :Autologous Whole BloodRpm/minutesPlatelet poor plasma andBuffy coatErythrocytRpm/minutesThe patient¡¯s blood is drawnPlatelets Poor PlasmaPlatelets Rich PlasmaSteps in the preparation of platelet-rich plasma.Platelet-rich plasma (in the syringe) and platelet-poor plasma (in the centrifugation tube). The latter can be used to cover the surgical area.
  • 7. HypothesisIf platelets concentrate could be brought to level greater than eight times baseline the physiological effects may be profoundly positive.(Dr Astley E Smith.,GlobalAutografting Institute)
  • 8. PRP AND HC PRP
  • 9. FIELDS APPLICATION of Platelets Rich Plasma
  • 10. Some Growth Factors Acting on ¡°Healing Cascade¡± In addition the activated thrombocytes have onto their surface a multitude of signalisation molecules eg. CD9, CD-W17, CD31, CD41, CD42a-d, CD51, CD-W60, CD61, CD62P, CD63
  • 11. Advantages of a-PlasmaTissue regeneration & rejuvenation: neo-collagenesis(TGF¦Á& ¦Â), neo-vascularisation(EGF & VEGF), & extracellularmatrix formation (PDGF¦Á¦Á& ¦Â¦Â& ¦Á¦Â) ¨CNB: growth factors in genetically pre-determined ratio!Bio-glue (fibrin glue): haemostasis & tissue adhesion in skin flaps, bone grafts, trauma intra-surgery and post-surgerySafety: non-allergenic & free from concerns over transmissible diseases e.g. HIV, Hepatitis B & C, CJD, etc.Autologous: no risk of rejection reactionWound healing time: increasedPhysiological ¡®anti-biotic¡¯: anti-bodies & WBC¡¯s& proteolyticenzymesPlasma includes: hormones, biotransformedvitamins & other nutrientsTissue engineering: in-vitro autologous tissue culture-medium.Ease of use: dermal & hypodermal injectionsConvenience: Plasma harvesting performed in doctor¡¯s rooms (no external laboratory required)
  • 13. Contra -IndicationsPlatelet Dysfunction SyndromeCritical ThrombocytopeniaHypofibrinogenaemiaHaemodynamicInstabilityAuto-immune diseaseMalignancySepsisAcute & Chronic InfectionsChronic Liver PathologyAnti-coagulation therapy Pregnancy (for cosmetic indications)
  • 15. AFTER ¨C 3 monthsBEFORE
  • 16. A ¨C 64 years ¨C old woman, injection by autologous PRP1 month after.
  • 17. After ¨C scratching by rat ¨C 3 weeks agoAcne Scar : Subcision + hc PRP : 1 month after
  • 18. 4 days after injectionsbefore
  • 19. Acne Scar : Dermaroller 1.5 mm + PRP Before1 week after(right side)
  • 20. Acne Scar + Subsicion + PRP 1 week afterSubsicion with NocorneedleBefore
  • 21. 3 weeks afterAlopecia ¨C 36 years old
  • 22. Alopecia and Marking3 weeks after Injeksi PRPIn Bulbus