The document discusses the nervous system, including the peripheral nervous system, spinal nerves, cranial nerves, and autonomic nervous system. It notes that the peripheral nervous system connects the brain and spinal cord to other parts of the body using cranial and spinal nerves. It describes the 31 pairs of spinal nerves and 12 pairs of cranial nerves. It also summarizes the sympathetic and parasympathetic divisions of the autonomic nervous system, describing their structures and neurotransmitters.
2. The Anatomy & Physiology
of the nervous system
Peripheral Nervous System
Includes nerves connecting the brain and
spinal cord to other parts of the body.
Includes Cranial and Spinal Nerves that
connect brain and spinal cord,
respectively, to peripheral structures such
as the skin surface and the skeletal
muscles.
3. The Anatomy & Physiology
of the nervous system
Spinal Nerves
31 pairs- contain
dendrites of sensory
neurons and axons of
motor neurons.
Conducts impulses
between the spinal
and the parts of the
body not supplied by
the cranial nerves.
4. The Anatomy & Physiology
of the nervous system
Dermatomes
5. The Anatomy & Physiology
of the nervous system
Cranial Nerves
6. The Anatomy & Physiology
of the nervous system
The 12 Cranial Nerves
CN I: OLFACTORY
FUNCTION:
Purely Sensory
PURPOSE:
Transmits sense of
smell
TEST:
Coffee Smell
ABNORMALITY:
Hyperosmia Acute
sense of smell
Parosmia Abnormal
sense of smell
Anosmia Loss of sense
of smell
7. The Anatomy & Physiology
of the nervous system
The 12 Cranial Nerves
CN II: OPTIC
FUNCTION:
Purely Sensory
PURPOSE:
Vision
TEST:
Ophthalmoscopy
Snellen Chart
Visual Field/COnfrontation
ABNORMALITY:
Blindnesss
Papilledema or choked
disc blurred optic disc
during ophthalmoscopy
8. The Anatomy & Physiology
of the nervous system
The 12 Cranial Nerves
CN III: OCULOMOTOR
FUNCTION:
Mainly Motor
PURPOSE:
Pupil constriction
Accomodation (4 eom)
TEST:
Pupil light reaction
Eyeball movements
ABNORMALITY:
Tropia muscle
weakness
Strabismus cross-eyed
9. The Anatomy & Physiology
of the nervous system
The 12 Cranial Nerves
CN IV: TROCHLEAR
FUNCTION:
Mainly Motor
PURPOSE:
Innervates SOM of the
eyeball, looking to the
umbilicus area (turns eye
down and laterally
TEST:
Extraocular movement
ABNORMALITY:
Nystagmus Rapid,
involuntary irregular
movement of the
eyeballs
Tropias weakness of
EOMs
10. The Anatomy & Physiology
of the nervous system
The 12 Cranial Nerves
CN V: TRIGEMINAL
FUNCTION:
Mixed
PURPOSE:
Masticate (motor)
Facial Sensation
Corneal Reflex
TEST:
Assess temporal/masseter muscle
strength, test the corneal reflex, and
sensation of pain, temp., & touch on
face
ABNORMALITY:
Trigeminal Neuralgia
neuropathic disorder of
1 or both trigeminal
nerves
11. The Anatomy & Physiology
of the nervous system
The 12 Cranial Nerves
CN VI: ABDUCENS
FUNCTION:
Mainly Motor
PURPOSE:
Innervates the lateral rectus
muscles, to the ear direction
TEST:
Extraocular movement
ABNORMALITY:
Diplopia double vision
12. The Anatomy & Physiology
of the nervous system
The 12 Cranial Nerves
CN VII: FACIAL NERVE
FUNCTION:
Mixed
PURPOSE:
Facial Expression, salivation & tearing,
Tasting in the anterior 2/3 of the tongue
Sensation in the ear
TEST:
Tearing: ammonia fumes
Facial Reactions
Test ability to taste sweet, salty, sour &
bitter substances.
ABNORMALITY:
Bells palsy paralysis of
the muscles of facial
expression and inability
to binl eyelids
13. The Anatomy & Physiology
of the nervous system
The 12 Cranial Nerves
CN VIII: ACOUSTIC
FUNCTION:
Purely Sensory
PURPOSE:
Hearing and Balance
TEST:
Screen hearing
Webers Test
Rinnes Test
ABNORMALITY:
Tinnitus ringing in the
ear/s
Menieres disease or
endolyphatic hydrops
14. The Anatomy & Physiology
of the nervous system
The 12 Cranial Nerves
CN IX:
GLOSSOPHARYNGEAL
FUNCTION:
Mixed
PURPOSE:
Taste in the posterior 1/3 of
the tongue; swallowing and
salivation
TEST:
Gag Reflex
Swallowing
ABNORMALITY:
Loss of Gag Reflex
Dysphagia Difficulty of
swallowing
15. The Anatomy & Physiology
of the nervous system
The 12 Cranial Nerves
CN X: VAGUS
FUNCTION:
Mixed
PURPOSE:
Laryngeal control, inhibits
HR, stimulates peristalsis
TEST:
Voice
HR
ABNORMALITY:
Dysphagia
Dysphonia impairment
of voice
16. The Anatomy & Physiology
of the nervous system
The 12 Cranial Nerves
CN XI: ACCESSORY
FUNCTION:
Mainly Motor
PURPOSE:
Movements of the head and
shrugging of shoulders
TEST:
Shoulder strength
Head Rotation
ABNORMALITY:
Difficulty in rotating
head and raising
shoulder/chin against
resistance
17. The Anatomy & Physiology
of the nervous system
The 12 Cranial Nerves
CN XII: HYPOGLOSSAL
FUNCTION:
Mainly Motor
PURPOSE:
Movement of the tongue
TEST:
Tongue deviations
ABNORMALITY:
Fasciculations coarse
involuntary movement
of the tongue
18. The Anatomy & Physiology
of the nervous system
Peripheral Nerve Disorders
Neuritis
damage to nerves of
the peripheral nervous
system,which may be
caused either by diseases
of or trauma to the
nerve or the side-effects of
systemic illness.
19. The Anatomy & Physiology
of the nervous system
Peripheral Nerve Disorders
Trigeminal Neuralgia
Compression or
degeneration of the fifth
cranial nerve, the
trigeminal nerve.
20. The Anatomy & Physiology
of the nervous system
Peripheral Nerve Disorders
Bells Palsy
Compression,
degeneration, or infection
of the seventh cranial
nerve (facial nerve).
21. The Anatomy & Physiology
of the nervous system
Peripheral Nerve Disorders
Herpes Zoster (Shingles)
Viral infection caused by
chickenpox virus that has
invaded the dorsal root
ganglion and remained
dormant until stress or
reduced immunity
precipitate an episode of
shingles.
22. The Anatomy & Physiology
of the nervous system
Review of the Major Divisions of the
Nervous System
23. The Anatomy & Physiology
of the nervous system
Autonomic Nervous System
It consists of motor neurons that conduct
impulses from the spinal cord or brainstem
to the following kinds of tissues:
1. Cardiac muscle tissue
2. Smooth muscle tissue
3. Glandular muscle tissue
24. The Anatomy & Physiology
of the nervous system
2 Subdivisions of the ANS
1. Sympathetic Nervous System
2. Parasympathetic Nervous System
25. The Anatomy & Physiology
of the nervous system
Functional Anatomy of the ANS
Autonomic Neurons make up the ANS.
Ganglia- is a biological tissue mass, most
commonly a mass of nerve cell bodies.
1. Preganglionic neurons conduct impulses
between the spinal cord and a ganglion.
2. Postganglionic neurons conduct impulses
from a ganglion to a cardiac muscle, smooth
muscle, or glandular epithelial tissue.
26. The Anatomy & Physiology
of the nervous system
Autonomic Conduction Path
28. The Anatomy & Physiology
of the nervous system
Sympathetic Nervous System
Functions as an emergency system of the
body. (Fight or Flight Response)
Impulses over sympathetic fibers take
control of many internal organs when we
exercise strenously and when strong
emotions (anger, fear, hate, anxiety) are
elicited.
29. The Anatomy & Physiology
of the nervous system
Sympathetic Nervous System
STRUCTURE
Sympathetic Preganglionic
Neurons- dendrites and
cell bodies in the gray
matter of the thoracic and
upper lumbar segments of
the spinal cord.
30. The Anatomy & Physiology
of the nervous system
Sympathetic Nervous System
STRUCTURE
Sympathetic Post
ganglionic Neurons-
dendrites and cell bodies
in sympathetic ganglia.
31. The Anatomy & Physiology
of the nervous system
Autonomic Neurotransmitters
32. The Anatomy & Physiology
of the nervous system
SNS Neurotransmitters
(Postganglionic Neurons-Effectors)
Norepinephrine/Epinephrine
4 Adrenergic Receptors
a) Alpha1
b) Alpha2
c) Beta1
d) Beta2
35. The Anatomy & Physiology
of the nervous system
Sympathetic Responses
Editor's Notes
#4: Conduct impulses necessary for sensations and voluntary movements.
#5: Adermatomeis an area ofskinthat is mainly supplied by a singlespinal nerve.
A dermatome is an area of skin supplied by sensory neurons that arise from a spinal nerve ganglion. Symptoms that follow a dermatome (e.g. like pain or a rash) may indicate a pathology that involves the related nerve root. Examples include somatic dysfunction of the spine or viral infection.Referred painusually involves a specific, "referred" location so is not associated with a dermatome.
Viruses that hibernate in nerve ganglia (e.g.Herpes zosterorVaricella Zosterviridae) often cause either pain, rash or both in a pattern defined by a dermatome. However, the symptoms may not appear across the entire dermatome.
#9: Medial rectus, Inferior rectus, Superior rectus, Inferior Oblique
#19: Sciatica a form of neuritis caused by a painful inflammation of the spinal nerve branch in the thigh called the sciatic nerve.
Characterized by nerve pain or neuralgia.
#20: Also called tic douloureux
Characterized by recurring episodes of:
Stabbing pain radiating from the angle of the jaw along a branch of the trigeminal nerve.
Nerve pain of one branch occurs over the forehead and around the eyes.
Pain along another branch is felt in the cheeck, nose, and upper lip.
Neuralgia of the third branch results in stabbing pains in the tongue and lower lip.
#21: Characterized by paralysis of some or all of the facial features innervated by the facial nerve, including the eyelids and mouth.
Often temporary but in some cases is irreversible.
Treatment: plastic surgery
#22: Varicella Zoster Virus
The virus travels through a cutaneous nerve and remains dormant in a dorsal root ganglion for years after an episode of the chickenpox.
After immune system is depressed, the virus travels over the sensory nerve to the skin of a single dermatome.
Resulting to:
Painful eruption of red, swollen plaques or vesicles that eventually rupture and crust before clearing in 2-3 weeks.
In severe cases, extensive inflammation, hemorrhagic blisters, and secondary bacterial infection may lead to permanent scarring.
In most cases, the eruption of vesicles is preceded by 4-5 days of pre-eruptive pain, burning, and itching in the affected dermatome.
Usually affects a single dermatome, producing characteristic painful plaques or vesicles.
Photograph of a 13 y/o boy with eruptions involving dermatome T4.
#24: The ANS consists of parts of the nervous system that regulate involuntary function.
On the other hand, motor nerves that control the voluntary actions of skeletal muscles are called the Somatic Nervous System.
#26: Dendrites and cell bodies of some autonomic neurons are locate in the gray matter of the spinal cord or brainstem.
Their axons extend from these structures and terminate in peripheral junction boxes called ganglia.
Visceral/Autonomic Effectors are the tissues to which autonomic neurons conduct impulses.
Cardiac muscle
Smooth Muscles of blood vessels and other hollow organs
Glandular Epithelial tissues secreting part of glands
#27: Conduction paths to visceral and somatic effectors from the CNS (spinal cord or brainstem) differ somewhat.
Autonomic paths to visceral effectors consist of two-neuron relays. Impulses travel over preganglionic neurons from the spinal cord or brainstem to autonomic ganglia. There they are relayed across synapses to postganglionic neurons, which then conduct impulses from the ganglia to visceral effectors.
Somatic motor neurons conduct all the way from the spinal cord or brainstem to somatic effectors with no intervening synapses.
#29: In short, when we must cope of stress of any kind, sympathetic impulses increase to many visceral effectors and rapidly produce widespread changes within our bodies.
Heart beats faster
Blood vessels constrict
Blood pressure increase
Blood vessels in skeletal muscles dilate. (supplying more blood to the muscles)
Sweat glands and adrenal glands secrete more abundantly.
Salivary and other digestive glands secrete more sparingly.
GUT (peristalsis) become sluggish hampering digestion.
All actions make us ready for strenous muscular work, or they prepare us for Fight or Flight.
The group of changes induced by sympathetic control is known as the fight or flight response.
#30: The axon of the preganglionic neuron leaves the spinal cord in the anterior (ventral) root of a spinal nerve. It next enters the spinal nerve but soon leaves it to extend to and through sympathetic ganglion and terminate in a collateral ganglion. There it synapses with several postganglionic neurons whose axons extend to terminte to visceral effectors.
Notice also that branches of the preganglionic axon may ascend or descend to terminate in ganglia above and below their point of origin. All sympathetic preganglionic axons therefore synapse with many postganglionic neurons, and these frequently terminate in widely separated organs.
Therefore sympathetic responsess are usually widespread, involving many organs rather than just one.
#31: Sympathetic ganglia are located in front and at each side of the spinal column.
Because short fibers extend between the sympathetic ganglia, they look a little like two chains of beads. (called sympathetic chain ganglia)
Axons of sympathetic postganglionic neurons travel in spinal nerves to blood vessels, sweat glands, and arrector hair muscles all over the body.
#32: The image illustrates information regarding autonomic neurotransmitters, the chemical compounds released from the axon terminals of autonomic neurons.
Notice that 3 axons on the image release acetylcholine therefore you call them as cholinergic fibers.
Only one type of autonomic axon releases the neurotransmitter norepinephrine (noradrenaline) this is the postganglionic neuron. Classified as adrenergic fibers.
#33: They act on one or more adrenergic receptors sites located on the cells of smooth muscles such as the heart, bronchiole walls, gastrointestinal tract, urinary bladder, and ciliary muscle of the eye. There are many adrenergic receptors; the four main receptors are alpha1, alpha2, beta1 and beta2 which mediate major responses.