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Sneha Susan JacobAgnes Maina
THE BIG HUB THEORY!Student: Agnes Maina, MSCM 2016
Student: Sneha Susan Jacob, MSCM 2016
Advisor: Dr. David Gonsalvez
Sponsor: A Global Pharmaceutical Company
 Lead Time reduction and faster responsiveness to demand volatility
 Hub-and-spoke model was born from industrys efforts to develop
more efficient networks. Benchmarking by the company has shown
that leading competitors have started developing a Hub.
Our Hub and Spoke Mental Model
 What is the impact of alternative operating policies and supply chain
parameters on the APAC hub supply chain performance?
 Develop an inventory control system to enable us infer the
operations of the secondary packaging hub
 A proposed hub system evaluated under various operating scenarios
by building a model of the product supply chain under analysis,
identifying key supply chain parameters and alternative operating
policies.
 A model and a tool that allows to simulate the expected output (stock
levels, write-off risks and service level) of alternative set of planning
parameters and policies.
 Apply the model to the pharmaceutical sector in general where there
is a set shelf life and set legal restrictions around the residual shelf
life.
 The overall lead-time must be reduced from the current 90 days for
all products and also reduce the review period for the temperature
controlled products; product MD, R and X so as to benefits from
lower costs at any given CSL.
 The hub needs to receive the product with an RSL of at least 10%
above the affiliates minimum acceptable RSL. This would aid reduce
chances of the products becoming obsolete or unqualified for
importation to the affiliates.
 Implementation of demand restriction on Safety Stock the low
volume products.
Methodology
The Problem
Motivation / Background
Key Question / Hypothesis
Relevant Literature
Results
Expected Contribution
 Current situation: Products are transported directly from the manufacturer to the
country where they are required.
 Implication: This in turn leads to long lead times which hinders the countries to
attend to urgent or unexpected demand.
January 2016 Poster Session
And a million other authors
Variables
Demand
Inventory
Policy
MOQ,
Safety
Stock
Lead
Time
8
10
12
14
16
18
20
22
24
26
28
30
89.5%
90.0%
90.5%
91.0%
91.5%
92.0%
92.5%
93.0%
93.5%
94.0%
94.5%
95.0%
95.5%
96.0%
96.5%
97.0%
97.5%
98.0%
98.5%
99.0%
99.5%
99.9%
Days
Cycle Service Level
Impact of Demand Restriction on Safety Stock (Days): Product MD
Demand Restricted at 1  Demand Restricted at 2  Unrestricted Demand

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Poster Presentation at MIT

  • 1. Sneha Susan JacobAgnes Maina THE BIG HUB THEORY!Student: Agnes Maina, MSCM 2016 Student: Sneha Susan Jacob, MSCM 2016 Advisor: Dr. David Gonsalvez Sponsor: A Global Pharmaceutical Company Lead Time reduction and faster responsiveness to demand volatility Hub-and-spoke model was born from industrys efforts to develop more efficient networks. Benchmarking by the company has shown that leading competitors have started developing a Hub. Our Hub and Spoke Mental Model What is the impact of alternative operating policies and supply chain parameters on the APAC hub supply chain performance? Develop an inventory control system to enable us infer the operations of the secondary packaging hub A proposed hub system evaluated under various operating scenarios by building a model of the product supply chain under analysis, identifying key supply chain parameters and alternative operating policies. A model and a tool that allows to simulate the expected output (stock levels, write-off risks and service level) of alternative set of planning parameters and policies. Apply the model to the pharmaceutical sector in general where there is a set shelf life and set legal restrictions around the residual shelf life. The overall lead-time must be reduced from the current 90 days for all products and also reduce the review period for the temperature controlled products; product MD, R and X so as to benefits from lower costs at any given CSL. The hub needs to receive the product with an RSL of at least 10% above the affiliates minimum acceptable RSL. This would aid reduce chances of the products becoming obsolete or unqualified for importation to the affiliates. Implementation of demand restriction on Safety Stock the low volume products. Methodology The Problem Motivation / Background Key Question / Hypothesis Relevant Literature Results Expected Contribution Current situation: Products are transported directly from the manufacturer to the country where they are required. Implication: This in turn leads to long lead times which hinders the countries to attend to urgent or unexpected demand. January 2016 Poster Session And a million other authors Variables Demand Inventory Policy MOQ, Safety Stock Lead Time 8 10 12 14 16 18 20 22 24 26 28 30 89.5% 90.0% 90.5% 91.0% 91.5% 92.0% 92.5% 93.0% 93.5% 94.0% 94.5% 95.0% 95.5% 96.0% 96.5% 97.0% 97.5% 98.0% 98.5% 99.0% 99.5% 99.9% Days Cycle Service Level Impact of Demand Restriction on Safety Stock (Days): Product MD Demand Restricted at 1 Demand Restricted at 2 Unrestricted Demand